SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6b9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)
6b9x HEPATITIS B VIRUS X
INTERACTING PROTEIN
RAGULATOR COMPLEX
PROTEIN LAMTOR4

(Homo
sapiens)
4 / 7 LEU E 119
GLN E 159
LEU D  46
VAL E 126
None
0.91A 3g8iA-6b9xE:
undetectable
3g8iA-6b9xE:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
6b9x HEPATITIS B VIRUS X
INTERACTING PROTEIN

(Homo
sapiens)
4 / 8 ASN E 153
HIS E 169
ASN E 155
MET E 171
None
1.01A 3kp6A-6b9xE:
undetectable
3kp6B-6b9xE:
undetectable
3kp6A-6b9xE:
23.63
3kp6B-6b9xE:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
6b9x HEPATITIS B VIRUS X
INTERACTING PROTEIN
RAGULATOR COMPLEX
PROTEIN LAMTOR1

(Homo
sapiens)
4 / 8 ILE A 124
GLU E 150
ILE E 158
LEU E 149
None
0.95A 4mj8A-6b9xA:
undetectable
4mj8A-6b9xA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1007_1
(SERUM ALBUMIN)
6b9x HEPATITIS B VIRUS X
INTERACTING PROTEIN
RAGULATOR COMPLEX
PROTEIN LAMTOR4

(Homo
sapiens)
5 / 9 LEU D  55
LEU E 130
ILE E 158
SER E 128
ALA E 124
None
1.15A 4z69A-6b9xD:
undetectable
4z69A-6b9xD:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)
6b9x HEPATITIS B VIRUS X
INTERACTING PROTEIN
RAGULATOR COMPLEX
PROTEIN LAMTOR4

(Homo
sapiens)
4 / 6 HIS D  56
ASN E 155
VAL E 168
LEU E 104
None
1.12A 5xdhA-6b9xD:
undetectable
5xdhC-6b9xD:
undetectable
5xdhA-6b9xD:
21.30
5xdhC-6b9xD:
21.30