SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bb4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
HEAVY CHAIN
MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus;
Mus
musculus) 		4 / 6 HIS L  91
GLY H  96
TYR L  49
GLU L  55
 None
SEP  P 396 ( 3.7A)
None
None
 0.89A 1dmaB-6bb4L:
undetectable		 1dmaB-6bb4L:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus) 		4 / 5 LEU L 179
GLY L 128
PRO L 120
VAL L 132
 None
 0.92A 2aojA-6bb4L:
undetectable		 2aojA-6bb4L:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
HEAVY CHAIN
MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus;
Mus
musculus) 		4 / 8 MET L 175
LEU L 136
SER H 178
VAL L 159
 None
 0.95A 2qd2A-6bb4L:
undetectable		 2qd2A-6bb4L:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
HEAVY CHAIN
MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus) 		3 / 3 SER L 100
THR L  97
PHE H  63
 None
 0.60A 2x91A-6bb4L:
undetectable		 2x91A-6bb4L:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus) 		5 / 12 PHE L  62
GLY L  16
LEU L  78
GLU L  79
SER L  76
 None
 1.32A 3tbgA-6bb4L:
undetectable		 3tbgA-6bb4L:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus) 		5 / 12 PHE L  62
GLY L  16
LEU L  78
GLU L  79
SER L  76
 None
 1.35A 3tbgC-6bb4L:
undetectable		 3tbgC-6bb4L:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus) 		4 / 4 LEU L  15
GLY L  16
LEU L  78
GLU L  79
 None
 1.05A 3tgvB-6bb4L:
undetectable		 3tgvB-6bb4L:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
HEAVY CHAIN
MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus;
Mus
musculus) 		5 / 12 ASN H  60
MET H  62
PHE H  63
ASP L   1
ARG H  40
 None
 1.27A 4djeA-6bb4H:
undetectable		 4djeA-6bb4H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus) 		3 / 3 LYS L  42
LYS L  39
PRO L  40
 None
 1.11A 4dv1L-6bb4L:
undetectable		 4dv1L-6bb4L:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
HEAVY CHAIN
MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus;
Mus
musculus) 		4 / 8 HIS L  91
GLY H  96
TYR L  49
GLU L  55
 None
SEP  P 396 ( 3.7A)
None
None
 0.92A 4hyfC-6bb4L:
undetectable		 4hyfC-6bb4L:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
HEAVY CHAIN
MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus) 		5 / 12 PHE L  36
PRO L  44
GLY L  41
PHE L  87
LEU H  45
 None
 1.16A 4kotA-6bb4L:
undetectable		 4kotA-6bb4L:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
HEAVY CHAIN
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  94
TYR H 102
 None
 0.31A 4m7kH-6bb4H:
27.2		 4m7kH-6bb4H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
HEAVY CHAIN
MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus;
Mus
musculus) 		4 / 5 GLY H 127
SER H 128
ALA H 129
PHE L 209
 None
 0.86A 4m93B-6bb4H:
23.5
4m93C-6bb4H:
17.5		 4m93B-6bb4H:
undetectable
4m93C-6bb4H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB304_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
HEAVY CHAIN
MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus;
Mus
musculus) 		4 / 4 GLY H 127
SER H 128
ARG H 213
PRO L 119
 None
 0.65A 4m93B-6bb4H:
23.5
4m93C-6bb4H:
17.5		 4m93B-6bb4H:
undetectable
4m93C-6bb4H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
HEAVY CHAIN
MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus;
Mus
musculus) 		3 / 3 ARG H  95
ASP H 101
TYR L  49
 SEP  P 396 ( 3.7A)
None
None
 0.96A 4yo9B-6bb4H:
undetectable		 4yo9B-6bb4H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
HEAVY CHAIN
(Mus
musculus) 		4 / 6 ASN H  76
ALA H  24
PRO H  52
TYR H  27
 None
 1.12A 5umd2-6bb4H:
undetectable
5umdF-6bb4H:
undetectable		 5umd2-6bb4H:
22.09
5umdF-6bb4H:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB302_1
(BIFUNCTIONAL PROTEIN
FOLD)		 6bb4 MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
HEAVY CHAIN
MOUSE MONOCLONAL
ANTIBODY C5.2 FAB
LIGHT CHAIN
(Mus
musculus) 		5 / 12 LEU H 124
PRO H 123
PHE L 135
THR H 165
VAL H 163
 None
 1.14A 6debB-6bb4H:
undetectable		 6debB-6bb4H:
25.27