SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bb9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 6bb9 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Salmonella
enterica) 		5 / 12 ILE A 234
ILE A 242
ARG A 117
SER A 114
LEU A 123
 None
 1.15A 1xdkB-6bb9A:
undetectable		 1xdkB-6bb9A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 6bb9 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Salmonella
enterica) 		5 / 12 LEU A 238
ALA A 237
LEU A  79
LEU A  39
PHE A 204
 None
MES  A 301 (-3.3A)
None
None
None
 1.39A 2oaxF-6bb9A:
undetectable		 2oaxF-6bb9A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 6bb9 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Salmonella
enterica) 		5 / 9 ALA A  18
GLY A  86
LEU A  12
ASN A   5
ILE A   4
 None
 1.15A 3wdmA-6bb9A:
undetectable		 3wdmA-6bb9A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 6bb9 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Salmonella
enterica) 		5 / 12 ILE A  83
GLN A  44
LEU A  46
LEU A  63
ILE A  36
 None
 1.14A 4g1bD-6bb9A:
undetectable		 4g1bD-6bb9A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 6bb9 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Salmonella
enterica) 		4 / 8 PHE A  57
THR A  62
VAL A  81
ILE A  83
 None
 0.99A 4l4cB-6bb9A:
undetectable		 4l4cB-6bb9A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 6bb9 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Salmonella
enterica) 		4 / 8 ILE A 242
ILE A 234
ASN A 236
ALA A 177
 None
None
CL  A 304 (-4.6A)
None
 0.88A 4ou1A-6bb9A:
undetectable		 4ou1A-6bb9A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 6bb9 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Salmonella
enterica) 		5 / 12 ASN A 198
VAL A 197
ILE A 242
ILE A 233
CYH A 205
 CL  A 305 ( 4.8A)
MES  A 301 (-4.1A)
None
None
None
 1.47A 4xueA-6bb9A:
undetectable		 4xueA-6bb9A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 6bb9 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Salmonella
enterica) 		4 / 5 ARG A 245
GLN A 119
ILE A 121
ASP A 160
 None
 1.33A 4z4hA-6bb9A:
undetectable		 4z4hA-6bb9A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 6bb9 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Salmonella
enterica) 		4 / 7 VAL A 171
ARG A 227
TYR A 247
GLU A 223
 None
 1.12A 5umwB-6bb9A:
undetectable
5umwE-6bb9A:
undetectable		 5umwB-6bb9A:
17.83
5umwE-6bb9A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 6bb9 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Salmonella
enterica) 		5 / 10 VAL A 226
ALA A 225
LEU A 163
LEU A 165
LEU A 179
 None
 0.97A 6f5uA-6bb9A:
undetectable
6f5uB-6bb9A:
undetectable		 6f5uA-6bb9A:
14.71
6f5uB-6bb9A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 6bb9 4-AMINO-4-DEOXYCHORI
SMATE LYASE
(Salmonella
enterica) 		5 / 10 VAL A 226
ALA A 225
LEU A 163
LEU A 165
LEU A 179
 None
 0.98A 6f6nA-6bb9A:
undetectable
6f6nB-6bb9A:
undetectable		 6f6nA-6bb9A:
14.71
6f6nB-6bb9A:
15.07