SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)
6bba ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT,
MITOCHONDRIAL

(Homo
sapiens)
5 / 10 ALA A 253
VAL A 262
GLY A 282
ILE A 283
ILE A 263
None
1.09A 4njuD-6bbaA:
undetectable
4njuD-6bbaA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)
6bba ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT,
MITOCHONDRIAL

(Homo
sapiens)
3 / 3 ARG A 114
GLU A 152
TYR A 116
None
0.81A 4r29D-6bbaA:
undetectable
4r29D-6bbaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)
6bba ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT,
MITOCHONDRIAL

(Homo
sapiens)
5 / 12 ALA A 194
PRO A 165
GLY A 198
GLY A 167
ALA A 204
None
1.13A 5c0oE-6bbaA:
undetectable
5c0oE-6bbaA:
undetectable