SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bcb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_A_DESA600_1
(ESTROGEN RECEPTOR
ALPHA)		 6bcb RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 18
(Mus
musculus) 		5 / 12 LEU A 340
LEU A 367
LEU A 368
LEU A 359
HIS A 435
 None
 1.07A 3erdA-6bcbA:
undetectable		 3erdA-6bcbA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 6bcb RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 18
(Mus
musculus) 		5 / 12 LEU A 340
LEU A 367
LEU A 368
LEU A 359
HIS A 435
 None
 1.11A 4zn7A-6bcbA:
undetectable		 4zn7A-6bcbA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 6bcb RHO GUANINE
NUCLEOTIDE EXCHANGE
FACTOR 18
(Mus
musculus) 		4 / 8 LEU A 363
LEU A 335
THR A 315
TYR A 377
 None
 1.15A 5hbsA-6bcbA:
undetectable		 5hbsA-6bcbA:
undetectable