SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bck'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
N49P7 FAB LIGHT
CHAIN FROM N49P7 IGG
(Homo
sapiens;
Homo
sapiens) 		4 / 7 HIS L  38
PRO L  44
PRO H  45
TYR H  91
 None
 0.66A 2oldA-6bckL:
25.3
2oldB-6bckL:
18.3		 2oldA-6bckL:
undetectable
2oldB-6bckL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
N49P7 FAB LIGHT
CHAIN FROM N49P7 IGG
(Homo
sapiens;
Homo
sapiens) 		4 / 7 HIS L  38
PRO L  44
PRO H  45
TYR H  91
 None
 0.65A 2ombC-6bckL:
24.7
2ombD-6bckL:
18.3		 2ombC-6bckL:
undetectable
2ombD-6bckL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
N49P7 FAB LIGHT
CHAIN FROM N49P7 IGG
(Homo
sapiens;
Homo
sapiens) 		3 / 3 VAL L 202
LYS L 204
HIS H 164
 None
 0.96A 3elzA-6bckL:
undetectable		 3elzA-6bckL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBR_A_ASDA129_1
(STEROID
DELTA-ISOMERASE)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
N49P7 FAB LIGHT
CHAIN FROM N49P7 IGG
(Homo
sapiens) 		5 / 12 PHE H 166
VAL L 195
VAL L 144
PRO L 113
PHE L 139
 None
 1.48A 3nbrA-6bckH:
undetectable		 3nbrA-6bckH:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG305_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
(Homo
sapiens) 		3 / 3 ASP H  85
ARG H  66
LYS H  83
 None
 0.91A 3wipG-6bckH:
undetectable		 3wipG-6bckH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
N49P7 FAB LIGHT
CHAIN FROM N49P7 IGG
(Homo
sapiens;
Homo
sapiens) 		4 / 8 ILE H  20
PRO L  44
VAL H  93
TRP H 103
 None
 1.15A 4f4dB-6bckH:
undetectable		 4f4dB-6bckH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_A_KANA600_1
(BIFUNCTIONAL AAC/APH)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
N49P7 FAB LIGHT
CHAIN FROM N49P7 IGG
(Homo
sapiens) 		5 / 12 ASP H 144
SER H 120
GLU L 124
SER L 121
GLU L 160
 None
 1.41A 5iqbA-6bckH:
undetectable		 5iqbA-6bckH:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_D_KAND600_1
(BIFUNCTIONAL AAC/APH)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
N49P7 FAB LIGHT
CHAIN FROM N49P7 IGG
(Homo
sapiens) 		5 / 12 ASP H 144
SER H 120
GLU L 124
SER L 121
GLU L 160
 None
 1.44A 5iqbD-6bckH:
undetectable		 5iqbD-6bckH:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_A_RIOA600_0
(BIFUNCTIONAL AAC/APH)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
N49P7 FAB LIGHT
CHAIN FROM N49P7 IGG
(Homo
sapiens;
Homo
sapiens) 		5 / 11 ASP H 144
SER H 120
GLU L 124
SER L 121
GLU L 160
 None
 1.42A 5iqdA-6bckH:
undetectable		 5iqdA-6bckH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_B_RIOB600_0
(BIFUNCTIONAL AAC/APH)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
N49P7 FAB LIGHT
CHAIN FROM N49P7 IGG
(Homo
sapiens;
Homo
sapiens) 		5 / 11 ASP H 144
SER H 120
GLU L 124
SER L 121
GLU L 160
 None
 1.42A 5iqdB-6bckH:
undetectable		 5iqdB-6bckH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQD_D_RIOD600_0
(BIFUNCTIONAL AAC/APH)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
N49P7 FAB LIGHT
CHAIN FROM N49P7 IGG
(Homo
sapiens;
Homo
sapiens) 		5 / 11 ASP H 144
SER H 120
GLU L 124
SER L 121
GLU L 160
 None
 1.47A 5iqdD-6bckH:
undetectable		 5iqdD-6bckH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_A_NMYA600_1
(BIFUNCTIONAL AAC/APH)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
N49P7 FAB LIGHT
CHAIN FROM N49P7 IGG
(Homo
sapiens) 		5 / 11 ASP H 144
SER H 120
GLU L 124
SER L 121
GLU L 160
 None
 1.45A 5iqeA-6bckH:
undetectable		 5iqeA-6bckH:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
N49P7 FAB LIGHT
CHAIN FROM N49P7 IGG
(Homo
sapiens) 		4 / 8 PRO H 167
THR L 161
THR L 162
PRO L 113
 None
 1.33A 5x2sI-6bckH:
undetectable
5x2sJ-6bckH:
undetectable
5x2sK-6bckH:
undetectable		 5x2sI-6bckH:
18.85
5x2sJ-6bckH:
18.88
5x2sK-6bckH:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 6bck N49P7 FAB HEAVY
CHAIN OF N29P7 IGG
(Homo
sapiens) 		3 / 3 PRO H 185
SER H 187
SER H 188
 None
 0.70A 6bpyA-6bckH:
undetectable		 6bpyA-6bckH:
undetectable