SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bdc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)		 6bdc HCP1
(Flavobacterium
johnsoniae) 		5 / 12 LEU A  83
PHE A  85
ILE A  44
LEU A   7
ILE A 111
 None
 1.18A 1re7B-6bdcA:
undetectable		 1re7B-6bdcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_B_ACTB1108_0
(C5A PEPTIDASE)		 6bdc HCP1
(Flavobacterium
johnsoniae) 		4 / 6 LEU A  23
GLY A  39
ASN A 125
ILE A 116
 None
 0.70A 1xf1B-6bdcA:
undetectable		 1xf1B-6bdcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_A_MTXA605_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 6bdc HCP1
(Flavobacterium
johnsoniae) 		5 / 12 LEU A  83
PHE A  85
SER A  68
ILE A  44
LEU A   7
 None
 1.09A 2oipA-6bdcA:
undetectable		 2oipA-6bdcA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 6bdc HCP1
(Flavobacterium
johnsoniae) 		5 / 12 LEU A  83
PHE A  85
SER A  68
ILE A  44
LEU A   7
 None
 1.11A 2oipD-6bdcA:
undetectable		 2oipD-6bdcA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_B_MTXB609_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 6bdc HCP1
(Flavobacterium
johnsoniae) 		5 / 12 LEU A  83
PHE A  85
SER A  68
ILE A  44
LEU A   7
 None
 1.12A 3hj3B-6bdcA:
undetectable		 3hj3B-6bdcA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJ3_D_MTXD615_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 6bdc HCP1
(Flavobacterium
johnsoniae) 		5 / 12 LEU A  83
PHE A  85
SER A  68
ILE A  44
LEU A   7
 None
 1.03A 3hj3D-6bdcA:
undetectable		 3hj3D-6bdcA:
12.02