SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6be3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 6be3 FAB (F598) HEAVY
CHAIN
(Homo
sapiens) 		5 / 12 ARG H  66
PRO H  41
LEU H  20
LEU H  18
ASP H  89
 None
 1.39A 1e7wA-6be3H:
undetectable		 1e7wA-6be3H:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 6be3 FAB (F598) HEAVY
CHAIN
(Homo
sapiens) 		5 / 11 TRP H  36
GLY H  49
ILE H  29
SER H  28
ASP H  98
 None
 1.33A 4rtrA-6be3H:
undetectable		 4rtrA-6be3H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 6be3 FAB (F598) HEAVY
CHAIN
(Homo
sapiens) 		5 / 12 MET H 119
SER H 188
LEU H 189
VAL H 161
HIS H 211
 None
 1.27A 5ubbA-6be3H:
undetectable		 5ubbA-6be3H:
undetectable