SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6beg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		4 / 8 ILE A 190
PHE A 202
LEU A  75
VAL A  90
 None
 0.82A 1fslB-6begA:
undetectable		 1fslB-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		4 / 8 LEU A 348
THR A 266
ILE A 271
TYR A 287
 None
 1.01A 1qvtA-6begA:
undetectable		 1qvtA-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		5 / 12 ILE A 332
LEU A 343
SER A 385
ILE A 384
LEU A 292
 None
 1.07A 1rx3A-6begA:
undetectable		 1rx3A-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		5 / 11 THR A 259
VAL A 505
VAL A 527
TYR A 258
GLU A 444
 None
 1.34A 1t6zB-6begA:
undetectable		 1t6zB-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		4 / 7 TYR A 116
CYH A 119
TYR A  92
ILE A 110
 None
 1.24A 2xz5B-6begA:
undetectable
2xz5E-6begA:
undetectable		 2xz5B-6begA:
undetectable
2xz5E-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		4 / 7 ILE A 178
ILE A  53
LEU A 171
LEU A  71
 None
 0.95A 3adxA-6begA:
undetectable		 3adxA-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		4 / 8 ASP A 425
TYR A 273
GLY A  85
ILE A 192
 FMT  A 601 (-3.7A)
None
None
None
 0.73A 3ihzB-6begA:
undetectable		 3ihzB-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		3 / 3 SER A 277
ASP A 137
ASP A 285
 None
 0.63A 3iv6C-6begA:
undetectable		 3iv6C-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		3 / 3 GLU A 230
LEU A 532
ASP A 531
 None
 0.46A 3ko0A-6begA:
undetectable		 3ko0A-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		4 / 6 PHE A 433
VAL A 521
THR A 266
PHE A 270
 FMT  A 601 (-4.7A)
None
None
None
 1.39A 3ltwA-6begA:
undetectable		 3ltwA-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		4 / 5 LEU A  66
LEU A 171
THR A 160
TRP A 108
 None
 1.43A 4do3A-6begA:
undetectable		 4do3A-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_A_ADNA401_1
(APH(2'')-ID)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		5 / 11 GLY A 141
LYS A 149
ILE A 192
LEU A 421
ILE A 138
 None
 1.01A 4dt8A-6begA:
undetectable		 4dt8A-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		5 / 12 LEU A 452
LEU A 443
ILE A 492
THR A 474
VAL A 246
 None
 1.13A 4f4dB-6begA:
undetectable		 4f4dB-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		4 / 6 PRO A  88
ILE A 428
TYR A 273
TYR A 283
 FMT  A 601 ( 4.9A)
FMT  A 601 ( 4.7A)
None
None
 1.07A 4g10A-6begA:
undetectable		 4g10A-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		4 / 5 TYR A 263
THR A 393
PHE A 270
ILE A 518
 None
None
None
EDO  A 604 (-3.8A)
 0.97A 4jx1E-6begA:
undetectable		 4jx1E-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		5 / 10 LEU A 452
LEU A 443
ILE A 492
THR A 474
VAL A 246
 None
 1.31A 4mk4A-6begA:
undetectable		 4mk4A-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		5 / 10 LEU A  39
LEU A 173
ILE A  63
LEU A  66
PHE A 214
 None
 1.08A 4odoC-6begA:
undetectable		 4odoC-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		5 / 12 LEU A 255
VAL A 507
LEU A 443
ARG A 475
SER A 460
 None
 1.46A 4po0A-6begA:
undetectable		 4po0A-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		5 / 12 ILE A 332
LEU A 343
SER A 385
ILE A 384
LEU A 292
 None
 1.07A 4qi9B-6begA:
undetectable		 4qi9B-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		4 / 7 LYS A 127
TYR A  89
TYR A 116
LEU A 115
 None
 1.23A 4yv5B-6begA:
undetectable		 4yv5B-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		4 / 8 SER A 256
THR A 476
THR A 474
PRO A 232
 None
 0.85A 5jhdE-6begA:
undetectable
5jhdG-6begA:
undetectable		 5jhdE-6begA:
undetectable
5jhdG-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		4 / 8 THR A 181
SER A  99
THR A 179
SER A 101
 None
 0.92A 5l4eA-6begA:
undetectable
5l4eB-6begA:
undetectable
5l4eC-6begA:
undetectable
5l4eD-6begA:
undetectable
5l4eE-6begA:
undetectable		 5l4eA-6begA:
undetectable
5l4eB-6begA:
undetectable
5l4eC-6begA:
undetectable
5l4eD-6begA:
undetectable
5l4eE-6begA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 6beg SCAFFOLD PROTEIN D13
(Vaccinia
virus) 		4 / 6 TYR A 306
LEU A 291
LYS A 417
LEU A 348
 None
 1.29A 5xooA-6begA:
undetectable		 5xooA-6begA:
undetectable