SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bfi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 6 VAL A 807
MET A 804
ILE A 729
ASN A 732
 None
 0.76A 1e06A-6bfiA:
undetectable		 1e06A-6bfiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 4 ARG A 700
ALA A 699
ALA A 681
GLU A 686
 None
 0.97A 1e7bA-6bfiA:
undetectable		 1e7bA-6bfiA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 4 ARG A 700
ALA A 699
ALA A 681
GLU A 686
 None
 1.00A 1e7bB-6bfiA:
3.5		 1e7bB-6bfiA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 5 ARG A 700
ALA A 699
ALA A 681
GLU A 686
 None
 1.07A 1e7cA-6bfiA:
undetectable		 1e7cA-6bfiA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 8 LEU A 292
ASP A 326
LEU A 325
LEU A 329
 None
 1.02A 1e7cA-6bfiA:
2.1		 1e7cA-6bfiA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 6bfi VIN1
(Oscarella
pearsei) 		5 / 12 LEU A 736
LEU A 691
ALA A 681
VAL A 677
ALA A 699
 None
 1.18A 1sa1A-6bfiA:
undetectable
1sa1B-6bfiA:
undetectable		 1sa1A-6bfiA:
12.05
1sa1B-6bfiA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 7 ALA A 425
PHE A 376
ARG A 488
GLU A 441
 None
 1.14A 1t9wA-6bfiA:
undetectable		 1t9wA-6bfiA:
7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TCT_A_CTCA222_0
(TETRACYCLINE
REPRESSOR)		 6bfi VIN1
(Oscarella
pearsei) 		5 / 12 PHE A 499
ARG A 536
GLN A 543
ILE A 507
SER A 503
 None
 1.48A 2tctA-6bfiA:
0.9		 2tctA-6bfiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 6bfi VIN1
(Oscarella
pearsei) 		5 / 10 VAL A 115
GLY A 114
GLY A  22
LEU A  24
LEU A 108
 None
 0.98A 2v3kA-6bfiA:
undetectable		 2v3kA-6bfiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 6bfi VIN1
(Oscarella
pearsei) 		5 / 10 ILE A 448
PHE A 403
ALA A 385
LEU A 386
ALA A 407
 None
 1.34A 3lw5B-6bfiA:
3.2		 3lw5B-6bfiA:
8.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 6 GLN A 358
ARG A 365
ASP A 280
GLU A 680
 None
 1.23A 4ax8A-6bfiA:
undetectable		 4ax8A-6bfiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 6 GLN A 358
ARG A 365
ASP A 280
GLU A 680
 None
 1.26A 4azvA-6bfiA:
undetectable		 4azvA-6bfiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D35_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 6 PHE A 499
GLU A 548
VAL A 547
ARG A 540
 None
 1.44A 4d35A-6bfiA:
undetectable
4d35B-6bfiA:
0.4		 4d35A-6bfiA:
11.97
4d35B-6bfiA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)		 6bfi VIN1
(Oscarella
pearsei) 		5 / 12 GLN A 345
ALA A 346
ALA A 350
VAL A 295
LEU A 292
 None
 1.10A 4j6dA-6bfiA:
undetectable		 4j6dA-6bfiA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 6bfi VIN1
(Oscarella
pearsei) 		5 / 12 GLN A 345
ALA A 346
ALA A 350
VAL A 295
LEU A 292
 None
 1.11A 4j6dB-6bfiA:
undetectable		 4j6dB-6bfiA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 6bfi VIN1
(Oscarella
pearsei) 		5 / 11 GLN A 345
ALA A 346
ALA A 350
VAL A 295
LEU A 292
 None
 1.13A 4jbtB-6bfiA:
undetectable		 4jbtB-6bfiA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6bfi VIN1
(Oscarella
pearsei) 		3 / 3 LEU A 185
ARG A 762
MET A 804
 None
 0.79A 4m11C-6bfiA:
undetectable		 4m11C-6bfiA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 6bfi VIN1
(Oscarella
pearsei) 		3 / 3 SER A 496
MET A 500
ASP A 375
 None
 0.87A 4mm4B-6bfiA:
undetectable		 4mm4B-6bfiA:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 6bfi VIN1
(Oscarella
pearsei) 		3 / 3 GLN A 277
HIS A 273
ARG A 812
 None
 1.01A 4qyqA-6bfiA:
undetectable		 4qyqA-6bfiA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 6bfi VIN1
(Oscarella
pearsei) 		3 / 3 GLN A 277
HIS A 273
ARG A 812
 None
 0.93A 4qyqB-6bfiA:
undetectable		 4qyqB-6bfiA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 7 GLU A 566
SER A 565
LYS A 546
VAL A 558
 None
 1.05A 4tvtA-6bfiA:
undetectable		 4tvtA-6bfiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 6 ASP A 789
ALA A 778
LYS A 719
THR A 709
 None
 1.38A 4w5qA-6bfiA:
undetectable		 4w5qA-6bfiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 4 ASN A 539
SER A 573
ALA A 535
VAL A 534
 None
 1.18A 4x1kC-6bfiA:
undetectable		 4x1kC-6bfiA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 6 ASP A 789
ALA A 778
LYS A 719
THR A 709
 None
 1.38A 4z4cA-6bfiA:
undetectable		 4z4cA-6bfiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 6 ASP A 789
ALA A 778
LYS A 719
THR A 709
 None
 1.40A 4z4fA-6bfiA:
undetectable		 4z4fA-6bfiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 6 ASP A 789
ALA A 778
LYS A 719
THR A 709
 None
 1.38A 4z4iA-6bfiA:
undetectable		 4z4iA-6bfiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 6bfi VIN1
(Oscarella
pearsei) 		5 / 10 ASP A 326
LEU A 325
LEU A 349
ALA A 353
LEU A 335
 None
 1.17A 4zbrA-6bfiA:
4.7		 4zbrA-6bfiA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 6bfi VIN1
(Oscarella
pearsei) 		5 / 11 ILE A 723
GLY A  22
ALA A 778
LEU A 722
GLU A  29
 None
 1.34A 5hw4B-6bfiA:
undetectable		 5hw4B-6bfiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 6bfi VIN1
(Oscarella
pearsei) 		5 / 12 PHE A   5
ILE A  14
MET A 795
ALA A 112
VAL A 776
 None
 1.13A 5mlmA-6bfiA:
undetectable		 5mlmA-6bfiA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 6bfi VIN1
(Oscarella
pearsei) 		5 / 12 ILE A  14
VAL A  51
LEU A  54
VAL A  13
PHE A  70
 None
 0.92A 5mugA-6bfiA:
undetectable		 5mugA-6bfiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 7 ARG A 457
LEU A 460
ALA A 389
LEU A 472
 None
 1.00A 5te8A-6bfiA:
0.0		 5te8A-6bfiA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 5 THR A 806
THR A 754
GLN A 758
ASP A 749
 None
 1.35A 6ectA-6bfiA:
undetectable		 6ectA-6bfiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 6bfi VIN1
(Oscarella
pearsei) 		4 / 5 THR A 806
THR A 754
GLN A 758
ASP A 749
 None
 1.39A 6ecxA-6bfiA:
undetectable		 6ecxA-6bfiA:
undetectable