SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bg8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 6bg8 IG DOMAIN PROTEIN,
GROUP 2 DOMAIN
PROTEIN
(Shewanella
frigidimarina) 		5 / 10 LEU A 102
ASN A 107
VAL A 128
VAL A 153
TYR A 183
 None
 1.38A 1fkoA-6bg8A:
undetectable		 1fkoA-6bg8A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 6bg8 IG DOMAIN PROTEIN,
GROUP 2 DOMAIN
PROTEIN
(Shewanella
frigidimarina) 		4 / 7 PRO A 116
LEU A 119
PHE A 154
PHE A 156
 None
 0.88A 2vcvL-6bg8A:
undetectable		 2vcvL-6bg8A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 6bg8 IG DOMAIN PROTEIN,
GROUP 2 DOMAIN
PROTEIN
(Shewanella
frigidimarina) 		5 / 12 THR A 217
ILE A 182
GLN A 178
ALA A 177
ILE A 174
 None
None
None
GOL  A 303 (-4.2A)
None
 1.20A 3ddyA-6bg8A:
undetectable		 3ddyA-6bg8A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 6bg8 IG DOMAIN PROTEIN,
GROUP 2 DOMAIN
PROTEIN
(Shewanella
frigidimarina) 		4 / 8 ILE A  22
TYR A  45
GLN A  20
LEU A  60
 None
 0.74A 3ozwA-6bg8A:
undetectable		 3ozwA-6bg8A:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 6bg8 IG DOMAIN PROTEIN,
GROUP 2 DOMAIN
PROTEIN
(Shewanella
frigidimarina) 		4 / 5 ARG A  42
GLY A  55
ALA A  54
GLY A  51
 None
 0.89A 4u9uA-6bg8A:
undetectable		 4u9uA-6bg8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 6bg8 IG DOMAIN PROTEIN,
GROUP 2 DOMAIN
PROTEIN
(Shewanella
frigidimarina) 		4 / 5 ARG A  42
GLY A  55
ALA A  54
GLY A  51
 None
 0.85A 4u9uB-6bg8A:
undetectable		 4u9uB-6bg8A:
undetectable