SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bgi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 6bgi ANOCTAMIN-1
(Mus
musculus) 		5 / 12 LEU A 643
GLY A 707
VAL A 709
LEU A 342
THR A 339
 CA  A1002 (-3.6A)
None
None
None
None
 0.97A 4m2vA-6bgiA:
undetectable		 4m2vA-6bgiA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 6bgi ANOCTAMIN-1
(Mus
musculus) 		5 / 12 ALA A 420
PHE A 412
ALA A 345
VAL A 348
TRP A 419
 None
 1.34A 4ryaA-6bgiA:
undetectable		 4ryaA-6bgiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 6bgi ANOCTAMIN-1
(Mus
musculus) 		5 / 12 THR A 535
ALA A 538
ALA A 517
ASN A 542
TYR A 594
 None
 1.07A 4u14A-6bgiA:
3.2		 4u14A-6bgiA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6bgi ANOCTAMIN-1
(Mus
musculus) 		4 / 5 SER A 401
ALA A 400
HIS A 402
LEU A 630
 None
 1.40A 5dzkb-6bgiA:
undetectable
5dzkp-6bgiA:
undetectable		 5dzkb-6bgiA:
undetectable
5dzkp-6bgiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6bgi ANOCTAMIN-1
(Mus
musculus) 		4 / 5 SER A 401
ALA A 400
HIS A 402
LEU A 630
 None
 1.43A 5dzkc-6bgiA:
undetectable
5dzkq-6bgiA:
undetectable		 5dzkc-6bgiA:
undetectable
5dzkq-6bgiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6bgi ANOCTAMIN-1
(Mus
musculus) 		4 / 5 SER A 401
ALA A 400
HIS A 402
LEU A 630
 None
 1.38A 5dzkf-6bgiA:
undetectable
5dzkt-6bgiA:
undetectable		 5dzkf-6bgiA:
undetectable
5dzkt-6bgiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 6bgi ANOCTAMIN-1
(Mus
musculus) 		4 / 5 PHE A 581
LEU A 711
GLY A 764
ILE A 759
 None
 0.93A 5ik1A-6bgiA:
1.1		 5ik1A-6bgiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 6bgi ANOCTAMIN-1
(Mus
musculus) 		4 / 8 THR A 422
MET A 416
ALA A 345
SER A 346
 None
 1.08A 5l5fY-6bgiA:
undetectable
5l5fZ-6bgiA:
undetectable		 5l5fY-6bgiA:
20.56
5l5fZ-6bgiA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 6bgi ANOCTAMIN-1
(Mus
musculus) 		3 / 3 LYS A 655
PRO A 654
LYS A 737
 None
 1.25A 5y9yA-6bgiA:
undetectable		 5y9yA-6bgiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 6bgi ANOCTAMIN-1
(Mus
musculus) 		3 / 3 LEU A 861
LEU A 857
ARG A 860
 None
 0.63A 6fgcA-6bgiA:
undetectable		 6fgcA-6bgiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 6bgi ANOCTAMIN-1
(Mus
musculus) 		3 / 3 LEU A 861
LEU A 857
ARG A 860
 None
 0.64A 6fgdA-6bgiA:
undetectable		 6fgdA-6bgiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 6bgi ANOCTAMIN-1
(Mus
musculus) 		4 / 4 ASP A 812
ILE A 782
PRO A 783
LEU A 785
 None
 1.38A 6mkeB-6bgiA:
undetectable		 6mkeB-6bgiA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 6bgi ANOCTAMIN-1
(Mus
musculus) 		4 / 4 ASP A 812
ILE A 782
PRO A 783
LEU A 785
 None
 1.38A 6mkeA-6bgiA:
undetectable		 6mkeA-6bgiA:
21.51