SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bhc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo
sapiens)
4 / 4 HIS A1373
LEU A1381
LEU A1507
LEU A1517
None
1.22A 1a4lD-6bhcA:
undetectable
1a4lD-6bhcA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo
sapiens)
4 / 4 ILE A1597
MET A1602
VAL A1553
GLY A1596
None
1.14A 1e06B-6bhcA:
undetectable
1e06B-6bhcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo
sapiens)
4 / 6 GLY A1596
ILE A1597
PRO A1626
ILE A1628
None
0.87A 1n49D-6bhcA:
undetectable
1n49D-6bhcA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo
sapiens)
5 / 11 LEU A1519
ALA A1642
VAL A1471
LEU A1524
LEU A1496
None
1.14A 1rlbF-6bhcA:
undetectable
1rlbF-6bhcA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo
sapiens)
3 / 3 SER A1554
ARG A1378
GLN A1388
None
0.87A 2xnrA-6bhcA:
undetectable
2xnrA-6bhcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo
sapiens)
5 / 12 LEU A1524
ASP A1473
VAL A1471
TYR A1489
HIS A1604
None
1.26A 3hgiA-6bhcA:
undetectable
3hgiA-6bhcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo
sapiens)
4 / 7 ASN A1386
LEU A1496
LEU A1723
PHE A1385
None
0.96A 3nk2X-6bhcA:
undetectable
3nk2X-6bhcA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo
sapiens)
4 / 6 LEU A1551
ASN A1386
MET A1602
LEU A1497
None
1.12A 4okbA-6bhcA:
undetectable
4okbA-6bhcA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo
sapiens)
4 / 6 LEU A1551
ASN A1386
MET A1602
LEU A1497
None
1.16A 4okxA-6bhcA:
undetectable
4okxA-6bhcA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo
sapiens)
5 / 10 LEU A1381
ASN A1386
VAL A1553
LEU A1551
LEU A1500
None
1.18A 4po0A-6bhcA:
undetectable
4po0A-6bhcA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_1
(MINERALOCORTICOID
RECEPTOR)
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo
sapiens)
4 / 6 GLN A1664
PHE A1730
CYH A1305
PHE A1706
None
1.38A 5mwyA-6bhcA:
undetectable
5mwyA-6bhcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_2
(WTFP-TAG,GP41)
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo
sapiens)
3 / 3 LEU A1667
LEU A1723
TRP A1722
None
0.74A 5nwuA-6bhcA:
undetectable
5nwuA-6bhcA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)
6bhc PSEUDOPODIUM-ENRICHE
D ATYPICAL KINASE 1

(Homo
sapiens)
4 / 6 GLU A1465
ARG A1550
PHE A1385
VAL A1383
None
1.18A 6fgdA-6bhcA:
undetectable
6fgdA-6bhcA:
undetectable