SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bhn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TKQ_B_DVAB6_0 (GRAMICIDIN A)	6bhn	METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR (Nostoc punctiforme)	3 / 3	ALA A 622 VAL A 639 TRP A 643	CYC A 800 ( 4.6A) None None	0.91A	1tkqB-6bhnA: undetectable	1tkqB-6bhnA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G72_A_SAMA2001_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	6bhn	METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR (Nostoc punctiforme)	5 / 12	TYR A 668 LEU A 714 ASP A 657 HIS A 659 ALA A 699	CYC A 800 (-3.9A) None CYC A 800 (-2.1A) CYC A 800 (-3.6A) None	1.12A	2g72A-6bhnA: undetectable	2g72A-6bhnA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7H_B_SAMB530_1 (TYPE I RESTRICTION ENZYME ECOKI M PROTEIN)	6bhn	METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR (Nostoc punctiforme)	3 / 3	TYR A 718 GLU A 637 THR A 653	None	0.72A	2y7hB-6bhnA: undetectable	2y7hB-6bhnA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_A_BQ1A1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	6bhn	METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR (Nostoc punctiforme)	3 / 3	GLU A 637 ALA A 636 PHE A 634	None None CYC A 800 (-3.9A)	0.64A	4v1fA-6bhnA: undetectable	4v1fA-6bhnA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	6bhn	METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR (Nostoc punctiforme)	3 / 3	GLU A 637 ALA A 636 PHE A 634	None None CYC A 800 (-3.9A)	0.62A	4v1fC-6bhnA: undetectable	4v1fC-6bhnA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TKQ_B_DVAB6_0","GRAMICIDIN A","6bhn","METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR","Nostoc punctiforme",3,"ALA A 622;VAL A 639;TRP A 643","CYC A 800 ( 4.6A);None;None","0.91A","1tkqB-6bhnA:undetectable","1tkqB-6bhnA:undetectable"],["2G72_A_SAMA2001_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","6bhn","METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR","Nostoc punctiforme",5,"TYR A 668;LEU A 714;ASP A 657;HIS A 659;ALA A 699","CYC A 800 (-3.9A);None;CYC A 800 (-2.1A);CYC A 800 (-3.6A);None","1.12A","2g72A-6bhnA:undetectable","2g72A-6bhnA:undetectable"],["2Y7H_B_SAMB530_1","TYPE I RESTRICTION ENZYME ECOKI M PROTEIN","6bhn","METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR","Nostoc punctiforme",3,"TYR A 718;GLU A 637;THR A 653","None","0.72A","2y7hB-6bhnA:undetectable","2y7hB-6bhnA:undetectable"],["4V1F_A_BQ1A1087_0","F0F1 ATP SYNTHASE SUBUNIT C","6bhn","METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR","Nostoc punctiforme",3,"GLU A 637;ALA A 636;PHE A 634","None;None;CYC A 800 (-3.9A)","0.64A","4v1fA-6bhnA:undetectable","4v1fA-6bhnA:undetectable"],["4V1F_C_BQ1C1087_0","F0F1 ATP SYNTHASE SUBUNIT C","6bhn","METHYL-ACCEPTING CHEMOTAXIS SENSORY TRANSDUCER WITH PHYTOCHROME SENSOR","Nostoc punctiforme",3,"GLU A 637;ALA A 636;PHE A 634","None;None;CYC A 800 (-3.9A)","0.62A","4v1fC-6bhnA:undetectable","4v1fC-6bhnA:undetectable"]]