SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bhq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)		 6bhq IGH PROTEIN
(Mus
musculus) 		5 / 11 GLY A 431
ILE A 369
THR A 370
GLY A 371
THR A 396
 None
 0.97A 4qgiA-6bhqA:
undetectable		 4qgiA-6bhqA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 6bhq IGH PROTEIN
(Mus
musculus) 		4 / 6 PRO A 374
ILE A 247
VAL A 379
THR A 396
 None
 1.14A 4xe5A-6bhqA:
undetectable		 4xe5A-6bhqA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 6bhq IGH PROTEIN
(Mus
musculus) 		4 / 8 GLU A 376
PRO A 339
ILE A 336
PRO A 244
 None
 1.13A 6a4iA-6bhqA:
undetectable		 6a4iA-6bhqA:
undetectable