SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bhv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		5 / 7 HIS A 862
GLY A 863
TYR A 896
TYR A 907
GLU A 988
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 (-3.7A)
DQV  A1101 (-3.3A)
 0.45A 1dmaA-6bhvA:
6.0		 1dmaA-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 6 HIS A 862
GLY A 863
TYR A 896
ALA A 898
TYR A 907
GLU A 988
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 ( 4.1A)
DQV  A1101 (-3.7A)
DQV  A1101 (-3.3A)
 0.44A 1dmaB-6bhvA:
6.2		 1dmaB-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		3 / 3 THR A 821
THR A 973
PRO A 956
 None
 0.87A 1fjaC-6bhvA:
undetectable		 1fjaC-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		3 / 3 THR A 821
THR A 973
PRO A 956
 None
 0.87A 1fjaD-6bhvA:
undetectable		 1fjaD-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		3 / 3 THR A 821
THR A 973
PRO A 956
 None
 0.82A 209dC-6bhvA:
undetectable		 209dC-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		4 / 7 PHE A1007
PHE A 869
ILE A 778
ILE A 801
 None
 1.00A 2v0mB-6bhvA:
undetectable		 2v0mB-6bhvA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		3 / 3 THR A 973
PRO A 956
THR A 821
 None
 0.87A 316dC-6bhvA:
undetectable		 316dC-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		3 / 3 TYR A 794
GLU A 840
ASP A 965
 None
 0.77A 3bxoA-6bhvA:
undetectable		 3bxoA-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		4 / 4 PRO A 970
TYR A 817
GLY A 972
THR A 973
 None
 1.25A 3ib0A-6bhvA:
undetectable		 3ib0A-6bhvA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 862
GLY A 863
TYR A 896
ALA A 898
LYS A 903
SER A 904
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 ( 4.1A)
DQV  A1101 ( 4.9A)
DQV  A1101 (-2.7A)
 0.96A 3u9hA-6bhvA:
19.2		 3u9hA-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 862
GLY A 863
TYR A 896
ALA A 898
SER A 904
TYR A 907
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 ( 4.1A)
DQV  A1101 (-2.7A)
DQV  A1101 (-3.7A)
 0.42A 3u9hA-6bhvA:
19.2		 3u9hA-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		4 / 8 HIS A 862
GLY A 863
TYR A 907
GLU A 988
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.7A)
DQV  A1101 (-3.3A)
 0.68A 3u9hA-6bhvA:
19.2		 3u9hA-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 862
GLY A 863
ALA A 898
SER A 904
TYR A 907
GLU A 988
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 ( 4.1A)
DQV  A1101 (-2.7A)
DQV  A1101 (-3.7A)
DQV  A1101 (-3.3A)
 0.90A 3u9hB-6bhvA:
19.2		 3u9hB-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 862
GLY A 863
TYR A 896
ALA A 898
LYS A 903
SER A 904
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 ( 4.1A)
DQV  A1101 ( 4.9A)
DQV  A1101 (-2.7A)
 1.00A 3u9hB-6bhvA:
19.2		 3u9hB-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 862
GLY A 863
TYR A 896
ALA A 898
SER A 904
TYR A 907
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 ( 4.1A)
DQV  A1101 (-2.7A)
DQV  A1101 (-3.7A)
 0.46A 3u9hB-6bhvA:
19.2		 3u9hB-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		5 / 6 HIS A 862
GLY A 863
TYR A 896
TYR A 907
GLU A 988
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 (-3.7A)
DQV  A1101 (-3.3A)
 0.57A 4ae1A-6bhvA:
6.5		 4ae1A-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		5 / 5 HIS A 862
GLY A 863
TYR A 896
TYR A 907
GLU A 988
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 (-3.7A)
DQV  A1101 (-3.3A)
 0.51A 4ae1B-6bhvA:
6.1		 4ae1B-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		5 / 8 HIS A 862
GLY A 863
SER A 904
TYR A 907
GLU A 988
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-2.7A)
DQV  A1101 (-3.7A)
DQV  A1101 (-3.3A)
 0.67A 4bjcA-6bhvA:
18.6		 4bjcA-6bhvA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 862
GLY A 863
TYR A 896
ALA A 898
LYS A 903
SER A 904
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 ( 4.1A)
DQV  A1101 ( 4.9A)
DQV  A1101 (-2.7A)
 0.96A 4bjcA-6bhvA:
18.6		 4bjcA-6bhvA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 862
GLY A 863
TYR A 896
ALA A 898
SER A 904
TYR A 907
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 ( 4.1A)
DQV  A1101 (-2.7A)
DQV  A1101 (-3.7A)
 0.35A 4bjcA-6bhvA:
18.6		 4bjcA-6bhvA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		7 / 7 HIS A 862
GLY A 863
TYR A 896
ALA A 898
SER A 904
TYR A 907
GLU A 988
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 ( 4.1A)
DQV  A1101 (-2.7A)
DQV  A1101 (-3.7A)
DQV  A1101 (-3.3A)
 0.54A 4hyfA-6bhvA:
20.1		 4hyfA-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		7 / 8 HIS A 862
GLY A 863
TYR A 896
ALA A 898
LYS A 903
SER A 904
GLU A 988
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 ( 4.1A)
DQV  A1101 ( 4.9A)
DQV  A1101 (-2.7A)
DQV  A1101 (-3.3A)
 0.82A 4hyfB-6bhvA:
20.2		 4hyfB-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		7 / 8 HIS A 862
GLY A 863
TYR A 896
ALA A 898
SER A 904
TYR A 907
GLU A 988
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 ( 4.1A)
DQV  A1101 (-2.7A)
DQV  A1101 (-3.7A)
DQV  A1101 (-3.3A)
 0.54A 4hyfB-6bhvA:
20.2		 4hyfB-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		8 / 8 HIS A 862
GLY A 863
TYR A 896
ALA A 898
LYS A 903
SER A 904
TYR A 907
GLU A 988
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-3.5A)
DQV  A1101 ( 4.1A)
DQV  A1101 ( 4.9A)
DQV  A1101 (-2.7A)
DQV  A1101 (-3.7A)
DQV  A1101 (-3.3A)
 0.48A 4hyfC-6bhvA:
20.3		 4hyfC-6bhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		4 / 4 LEU A 860
LEU A 964
GLN A 996
GLU A 844
 None
 1.12A 4i41A-6bhvA:
undetectable		 4i41A-6bhvA:
13.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RV6_A_RPBA1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		9 / 11 HIS A 862
GLY A 863
TYR A 889
TYR A 896
ALA A 898
LYS A 903
SER A 904
TYR A 907
GLU A 988
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-4.2A)
DQV  A1101 (-3.5A)
DQV  A1101 ( 4.1A)
DQV  A1101 ( 4.9A)
DQV  A1101 (-2.7A)
DQV  A1101 (-3.7A)
DQV  A1101 (-3.3A)
 0.38A 4rv6A-6bhvA:
38.5		 4rv6A-6bhvA:
32.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RV6_B_RPBB1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		9 / 11 HIS A 862
GLY A 863
TYR A 889
TYR A 896
ALA A 898
LYS A 903
SER A 904
TYR A 907
GLU A 988
 DQV  A1101 (-3.6A)
DQV  A1101 (-3.8A)
DQV  A1101 (-4.2A)
DQV  A1101 (-3.5A)
DQV  A1101 ( 4.1A)
DQV  A1101 ( 4.9A)
DQV  A1101 (-2.7A)
DQV  A1101 (-3.7A)
DQV  A1101 (-3.3A)
 0.37A 4rv6B-6bhvA:
39.9		 4rv6B-6bhvA:
32.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		4 / 5 PHE A 897
GLY A 922
ILE A 895
LEU A 920
 None
 0.81A 5dzkd-6bhvA:
undetectable
5dzkk-6bhvA:
undetectable
5dzky-6bhvA:
undetectable		 5dzkd-6bhvA:
undetectable
5dzkk-6bhvA:
undetectable
5dzky-6bhvA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 6bhv POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		7 / 9 HIS A 862
SER A 864
ASN A 868
ILE A 872
TYR A 896
SER A 904
TYR A 907
 DQV  A1101 (-3.6A)
DQV  A1101 (-2.9A)
DQV  A1101 (-4.2A)
DQV  A1101 (-4.5A)
DQV  A1101 (-3.5A)
DQV  A1101 (-2.7A)
DQV  A1101 (-3.7A)
 0.47A 5ha9B-6bhvA:
35.3		 5ha9B-6bhvA:
31.32