SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bj9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		4 / 8 GLY A 341
GLU A 314
PHE A 196
HIS A 360
 None
 0.90A 1ax9A-6bj9A:
undetectable		 1ax9A-6bj9A:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		4 / 8 GLY A 342
GLU A 314
PHE A 196
HIS A 360
 None
 0.91A 1ax9A-6bj9A:
undetectable		 1ax9A-6bj9A:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 PRO A  61
GLY A 116
GLY A  33
VAL A 256
MET A 258
 None
 1.23A 1ffyA-6bj9A:
undetectable		 1ffyA-6bj9A:
6.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 ASN A  88
THR A  30
VAL A  29
ALA A  86
ALA A  69
 None
 1.02A 1n5xA-6bj9A:
undetectable		 1n5xA-6bj9A:
5.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 ASN A  88
THR A  30
VAL A  29
ALA A  86
ALA A  69
 None
 1.02A 1n5xB-6bj9A:
undetectable		 1n5xB-6bj9A:
5.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		4 / 7 GLY A 341
GLU A 314
PHE A 196
HIS A 360
 None
 0.91A 2ackA-6bj9A:
undetectable		 2ackA-6bj9A:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 PHE A  55
GLY A  57
GLY A 117
ALA A 254
ASN A  88
 None
 1.15A 2dpmA-6bj9A:
undetectable		 2dpmA-6bj9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		4 / 8 ALA A 246
ALA A 320
GLY A 289
ALA A 318
 None
 0.87A 2vh3B-6bj9A:
undetectable		 2vh3B-6bj9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 GLY A 383
GLY A 289
VAL A 165
PHE A 169
ILE A 290
 None
 1.02A 3eluA-6bj9A:
undetectable		 3eluA-6bj9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		4 / 5 ILE A 195
TYR A 220
ILE A 200
HIS A 363
 None
 1.24A 3eteB-6bj9A:
undetectable
3eteC-6bj9A:
undetectable		 3eteB-6bj9A:
10.74
3eteC-6bj9A:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 ILE A  56
GLY A  57
ILE A 350
ALA A  86
VAL A  72
 None
 1.02A 3fpjA-6bj9A:
undetectable		 3fpjA-6bj9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 9 MET A 275
ALA A 273
LEU A 365
ILE A 310
ILE A 386
 None
 1.09A 3jw3B-6bj9A:
undetectable		 3jw3B-6bj9A:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 GLY A  11
GLY A  39
ALA A  13
ALA A 254
ALA A 253
 None
 0.89A 3sudA-6bj9A:
undetectable		 3sudA-6bj9A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 GLY A  11
GLY A  39
ALA A  13
ALA A 254
ALA A 253
 None
 0.90A 3sudD-6bj9A:
undetectable		 3sudD-6bj9A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 LEU A 300
GLY A 384
GLY A 279
ILE A 386
ALA A 374
 None
 1.17A 3uj7B-6bj9A:
undetectable		 3uj7B-6bj9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 GLY A 116
ALA A 253
ILE A  98
LEU A  37
VAL A 256
 None
 1.27A 4azwA-6bj9A:
undetectable		 4azwA-6bj9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 ALA A 355
GLY A  94
SER A  93
ASN A 316
GLY A 359
 None
 1.16A 4obwA-6bj9A:
undetectable		 4obwA-6bj9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 ALA A 355
GLY A  94
SER A  93
ILE A 357
GLY A 359
 None
 1.12A 4obwA-6bj9A:
undetectable		 4obwA-6bj9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 ALA A  97
ALA A  86
VAL A  87
GLY A 117
GLY A  94
 None
 1.02A 4rn6B-6bj9A:
undetectable		 4rn6B-6bj9A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 ALA A 253
GLY A  57
GLY A 117
GLY A 354
ALA A  69
 None
 1.06A 5c0oE-6bj9A:
undetectable		 5c0oE-6bj9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		4 / 5 ALA A 343
GLU A 317
ASN A 338
GLU A 314
 None
 1.50A 5dwkC-6bj9A:
undetectable		 5dwkC-6bj9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 GLU A  35
LEU A  41
LYS A  38
GLY A  75
ALA A  54
 None
 1.30A 5kbwA-6bj9A:
undetectable		 5kbwA-6bj9A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 GLU A  35
LEU A  41
LYS A  38
GLY A  75
ALA A  54
 None
 1.41A 5kbwB-6bj9A:
undetectable		 5kbwB-6bj9A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		3 / 3 MET A 352
GLU A 199
ARG A 356
 None
 0.96A 5tjyA-6bj9A:
undetectable		 5tjyA-6bj9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		3 / 3 MET A 352
GLU A 199
ARG A 356
 None
 1.00A 5tjzA-6bj9A:
undetectable		 5tjzA-6bj9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 VAL A 322
PHE A 288
MET A 121
VAL A  59
GLY A 379
 None
 1.42A 6brdA-6bj9A:
undetectable		 6brdA-6bj9A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 GLY A 116
GLY A 117
VAL A  58
VAL A  29
GLY A 252
 None
 0.99A 6gneA-6bj9A:
undetectable		 6gneA-6bj9A:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		5 / 12 GLY A 116
GLY A 117
VAL A  58
VAL A  29
GLY A 252
 None
 0.98A 6gneB-6bj9A:
undetectable		 6gneB-6bj9A:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 6bj9 ACETYL-COA
ACETYLTRANSFERASE A
(Ascaris
suum) 		4 / 7 ASP A 217
ARG A 356
GLU A 199
GLU A 314
 None
 1.14A 6mn5E-6bj9A:
undetectable		 6mn5E-6bj9A:
25.81