SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bk6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 6bk6 HENDRA VIRUS MATRIX
PROTEIN
(Hendra
henipavirus) 		5 / 10 GLY A 130
PHE A 129
SER A 131
LEU A 145
LEU A 113
 None
 1.39A 1a8uA-6bk6A:
undetectable		 1a8uA-6bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 6bk6 HENDRA VIRUS MATRIX
PROTEIN
(Hendra
henipavirus) 		5 / 10 GLY A 130
PHE A 129
SER A 131
LEU A 145
LEU A 113
 None
 1.40A 1a8uB-6bk6A:
undetectable		 1a8uB-6bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 6bk6 HENDRA VIRUS MATRIX
PROTEIN
(Hendra
henipavirus) 		4 / 6 HIS A 238
LEU A 206
LEU A 237
MET A 236
 None
 1.13A 1hz4A-6bk6A:
undetectable		 1hz4A-6bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 6bk6 HENDRA VIRUS MATRIX
PROTEIN
(Hendra
henipavirus) 		5 / 12 THR A 179
GLY A 269
SER A 270
GLY A 272
ILE A 278
 None
 0.89A 2b25B-6bk6A:
undetectable		 2b25B-6bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 6bk6 HENDRA VIRUS MATRIX
PROTEIN
(Hendra
henipavirus) 		5 / 12 THR A 179
GLY A 269
SER A 270
GLY A 273
ILE A 278
 None
 0.92A 2b25B-6bk6A:
undetectable		 2b25B-6bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 6bk6 HENDRA VIRUS MATRIX
PROTEIN
(Hendra
henipavirus) 		5 / 12 ILE A 259
ARG A 322
ALA A 324
ALA A 325
VAL A 326
 CME  A 255 ( 4.0A)
None
None
None
None
 0.94A 2oc8A-6bk6A:
undetectable		 2oc8A-6bk6A:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 6bk6 HENDRA VIRUS MATRIX
PROTEIN
(Hendra
henipavirus) 		5 / 12 ILE A 271
GLY A 272
GLY A 273
PRO A  93
ALA A  91
 None
 0.99A 3jayA-6bk6A:
undetectable		 3jayA-6bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 6bk6 HENDRA VIRUS MATRIX
PROTEIN
(Hendra
henipavirus) 		3 / 3 TYR A 187
MET A 262
LEU A 288
 None
 0.84A 3vw1D-6bk6A:
undetectable		 3vw1D-6bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 6bk6 HENDRA VIRUS MATRIX
PROTEIN
(Hendra
henipavirus) 		5 / 12 ASP A 304
ILE A 305
ILE A 271
GLY A 272
LEU A 276
 None
 1.04A 5twjC-6bk6A:
undetectable		 5twjC-6bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 6bk6 HENDRA VIRUS MATRIX
PROTEIN
(Hendra
henipavirus) 		5 / 12 ILE A 178
LEU A  94
GLY A  95
ALA A  91
ASP A 105
 None
 1.16A 5x66A-6bk6A:
undetectable
5x66B-6bk6A:
undetectable		 5x66A-6bk6A:
13.15
5x66B-6bk6A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 6bk6 HENDRA VIRUS MATRIX
PROTEIN
(Hendra
henipavirus) 		5 / 10 LEU A 194
ILE A 278
LEU A 206
LEU A 327
ALA A 203
 None
None
None
CME  A 255 ( 4.7A)
None
 1.14A 5y7pG-6bk6A:
undetectable		 5y7pG-6bk6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 6bk6 HENDRA VIRUS MATRIX
PROTEIN
(Hendra
henipavirus) 		5 / 12 ASN A 205
LEU A 239
ASP A 260
GLY A 347
PHE A 266
 None
 1.29A 6dwnA-6bk6A:
undetectable		 6dwnA-6bk6A:
15.48