SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bk7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 9 LEU A 278
LEU A 271
ILE A  30
VAL A 105
PHE A 133
None
1.37A 1gx8A-6bk7A:
undetectable
1gx8A-6bk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
4 / 8 GLY A 243
ARG A 245
ILE A 249
ASP A 276
None
0.84A 1jg4A-6bk7A:
undetectable
1jg4A-6bk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_1
(DNA GYRASE SUBUNIT B)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 GLU A  91
ASP A  87
ILE A  90
ILE A 400
THR A  89
None
1.35A 1kijA-6bk7A:
undetectable
1kijA-6bk7A:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
4 / 8 GLY A 259
TYR A 186
ILE A 175
GLU A 184
None
0.87A 1mrjA-6bk7A:
undetectable
1mrjA-6bk7A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 10 GLY A  22
ALA A  21
ASP A  20
GLY A  84
VAL A 103
None
0.95A 1t3rA-6bk7A:
undetectable
1t3rA-6bk7A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 THR A  26
GLY A 259
SER A 260
ASP A 177
ILE A 162
None
1.05A 2b25B-6bk7A:
undetectable
2b25B-6bk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 GLY A  22
ALA A  21
ASP A  20
GLY A  84
VAL A 103
None
0.90A 2ienB-6bk7A:
undetectable
2ienB-6bk7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_1
(PROTEASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 GLY A  22
ALA A  21
ASP A  20
GLY A  84
VAL A 103
None
0.97A 2nnkA-6bk7A:
undetectable
2nnkA-6bk7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
3 / 3 ARG A 300
THR A 292
VAL A 395
None
0.97A 2q64A-6bk7A:
undetectable
2q64A-6bk7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 LEU A  96
LEU A  99
LEU A 278
PRO A 279
VAL A 251
None
1.35A 2qd4B-6bk7A:
2.7
2qd4B-6bk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 11 LEU A 257
ILE A 162
PHE A 144
ALA A 159
LEU A 214
None
1.11A 2qjuA-6bk7A:
undetectable
2qjuA-6bk7A:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 PHE A 313
ARG A 130
GLY A  14
ILE A 373
ASP A 372
None
1.45A 2zznB-6bk7A:
undetectable
2zznB-6bk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 GLY A  22
ALA A  21
ASP A  20
GLY A  84
VAL A 103
None
0.99A 3cyxA-6bk7A:
undetectable
3cyxA-6bk7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
3 / 3 ARG A 300
GLU A 398
ASP A 404
None
0.60A 3g2oA-6bk7A:
undetectable
3g2oA-6bk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 GLY A  22
ALA A  21
ASP A  20
GLY A  84
VAL A 103
None
0.99A 3k4vD-6bk7A:
undetectable
3k4vD-6bk7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 10 GLY A  22
ALA A  21
ASP A  20
GLY A  84
VAL A 103
None
0.93A 3lzvA-6bk7A:
undetectable
3lzvA-6bk7A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 GLY A  22
ALA A  21
ASP A  20
GLY A  84
VAL A 103
None
0.97A 3ndtD-6bk7A:
undetectable
3ndtD-6bk7A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 10 GLY A  22
ALA A  21
ASP A  20
GLY A  84
VAL A 103
None
0.94A 3oy4B-6bk7A:
undetectable
3oy4B-6bk7A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 ARG A 130
ALA A 123
ILE A 131
MET A 270
LYS A  23
None
1.31A 3qt0A-6bk7A:
undetectable
3qt0A-6bk7A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 GLY A  22
ALA A  21
ASP A  20
GLY A  84
VAL A 103
None
1.00A 3tkgC-6bk7A:
undetectable
3tkgC-6bk7A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
4 / 5 ASP A 372
GLU A   4
TYR A 369
ASP A 304
None
1.25A 3w9tD-6bk7A:
undetectable
3w9tD-6bk7A:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 10 GLY A  22
ALA A  21
ASP A  20
GLY A  84
VAL A 103
None
0.99A 4dqhB-6bk7A:
undetectable
4dqhB-6bk7A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
4 / 6 ARG A  11
GLU A   8
ASP A 283
ARG A 245
None
1.41A 4kcnA-6bk7A:
undetectable
4kcnA-6bk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 PHE A 145
ILE A 176
ILE A 175
GLY A 167
ALA A 168
None
1.09A 4nkvA-6bk7A:
undetectable
4nkvA-6bk7A:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 PHE A 145
ILE A 176
ILE A 175
GLY A 167
ALA A 168
None
1.09A 4nkvC-6bk7A:
undetectable
4nkvC-6bk7A:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 PHE A 145
ILE A 176
ILE A 175
GLY A 167
ALA A 168
None
1.09A 4nkvD-6bk7A:
undetectable
4nkvD-6bk7A:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 PHE A 145
ILE A 176
ILE A 175
GLY A 167
ALA A 168
None
1.06A 4nkxA-6bk7A:
undetectable
4nkxA-6bk7A:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 9 GLY A  22
ALA A  21
ASP A  20
GLY A  84
VAL A 103
None
0.92A 4q1wA-6bk7A:
undetectable
4q1wA-6bk7A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 10 GLY A  22
ALA A  21
ASP A  20
GLY A  84
VAL A 103
None
0.93A 4q1yA-6bk7A:
undetectable
4q1yA-6bk7A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
4 / 7 THR A 325
GLY A 378
ALA A 376
ILE A 351
None
0.93A 4txnA-6bk7A:
undetectable
4txnA-6bk7A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
4 / 7 THR A 325
GLY A 378
ALA A 376
ILE A 351
None
0.91A 4txnB-6bk7A:
2.1
4txnB-6bk7A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
4 / 7 THR A 325
GLY A 378
ALA A 376
ILE A 351
None
0.92A 4txnC-6bk7A:
2.4
4txnC-6bk7A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
4 / 7 THR A 325
GLY A 378
ALA A 376
ILE A 351
None
0.93A 4txnD-6bk7A:
2.8
4txnD-6bk7A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_D_NOVD2000_1
(DNA GYRASE SUBUNIT B)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 GLU A  91
ASP A  87
ILE A  90
ILE A 400
THR A  89
None
1.38A 4uroD-6bk7A:
undetectable
4uroD-6bk7A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 10 PHE A 308
ALA A 309
VAL A 340
LEU A 379
THR A 382
None
1.23A 4zmeB-6bk7A:
undetectable
4zmeB-6bk7A:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
4 / 5 TYR A 186
PHE A 144
LEU A 257
PRO A 165
None
1.38A 5csyB-6bk7A:
undetectable
5csyB-6bk7A:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
3 / 3 ILE A 164
PRO A 165
ILE A 176
None
0.43A 5hw8F-6bk7A:
undetectable
5hw8F-6bk7A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 10 ILE A 351
PHE A 308
ALA A 376
PHE A 327
VAL A 329
None
1.16A 5m0oA-6bk7A:
undetectable
5m0oA-6bk7A:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 9 LEU A 106
VAL A 148
LEU A 151
ILE A 131
PRO A 161
None
1.07A 5og9A-6bk7A:
undetectable
5og9A-6bk7A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 LEU A 106
VAL A 148
LEU A 151
ILE A 131
PRO A 161
None
1.05A 5og9B-6bk7A:
undetectable
5og9B-6bk7A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
3 / 3 MET A 181
GLU A 212
ARG A 211
None
1.10A 5tjyA-6bk7A:
5.1
5tjyA-6bk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
3 / 3 MET A 181
GLU A 212
ARG A 211
None
0.98A 5tjzA-6bk7A:
5.2
5tjzA-6bk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
3 / 3 THR A  68
MET A 357
HIS A 358
None
0.87A 5uunA-6bk7A:
undetectable
5uunA-6bk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
3 / 3 ASP A 100
ASN A  12
ASP A 372
None
0.78A 5vopA-6bk7A:
undetectable
5vopA-6bk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
3 / 3 ASP A 100
ASN A  12
ASP A 372
None
0.74A 5vopB-6bk7A:
undetectable
5vopB-6bk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)
6bk7 ELONGATION FACTOR G
(Enterococcus
faecalis)
5 / 12 LEU A 334
GLU A 349
VAL A 340
THR A 317
GLY A 322
None
1.18A 5xipC-6bk7A:
2.3
5xipC-6bk7A:
undetectable