SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bka'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		5 / 12 GLY A 350
ASN A  75
SER A 145
ILE A 143
ILE A  19
 FMN  A 401 ( 3.9A)
None
None
None
None
 1.01A 1q8jB-6bkaA:
6.9		 1q8jB-6bkaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		5 / 12 PHE A 176
ALA A 238
ILE A 220
ILE A 224
LEU A 250
 None
FMN  A 401 ( 4.0A)
None
None
None
 1.08A 2bjfA-6bkaA:
undetectable		 2bjfA-6bkaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_3
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		5 / 12 ARG A 123
TYR A 119
GLY A 199
ASN A 297
LEU A 315
 None
 1.42A 2nyrB-6bkaA:
undetectable		 2nyrB-6bkaA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLC_A_CHDA332_0
(CHOLOYLGLYCINE
HYDROLASE)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		5 / 12 PHE A 176
ALA A 238
ILE A 220
ILE A 224
LEU A 250
 None
FMN  A 401 ( 4.0A)
None
None
None
 1.09A 2rlcA-6bkaA:
undetectable		 2rlcA-6bkaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		5 / 12 GLY A  47
PHE A 148
HIS A  81
PRO A 322
ARG A 296
 None
 1.26A 2y7kC-6bkaA:
undetectable		 2y7kC-6bkaA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		4 / 5 VAL A 168
GLN A 190
PHE A 234
ARG A 198
 None
FMN  A 401 (-3.9A)
None
None
 1.46A 3bjwE-6bkaA:
undetectable		 3bjwE-6bkaA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		5 / 9 LEU A 184
ASP A 185
ASP A 163
VAL A 144
ILE A 166
 None
 1.46A 3wsjA-6bkaA:
undetectable		 3wsjA-6bkaA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		4 / 8 ASP A 208
ASN A 297
GLY A 191
GLN A 190
 None
None
None
FMN  A 401 (-3.9A)
 0.98A 4af0A-6bkaA:
6.8		 4af0A-6bkaA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		4 / 8 LEU A  29
THR A  36
ALA A  32
SER A  27
 None
 0.81A 4ik7B-6bkaA:
undetectable		 4ik7B-6bkaA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		5 / 12 MET A  46
VAL A  74
LEU A  76
ALA A  32
LEU A  29
 None
 1.40A 4m11D-6bkaA:
undetectable		 4m11D-6bkaA:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		5 / 12 GLY A 240
GLY A 239
GLY A 195
ILE A 301
SER A 302
 FMN  A 401 (-3.4A)
FMN  A 401 (-3.2A)
FMN  A 401 (-3.7A)
None
None
 0.98A 4rtmA-6bkaA:
undetectable		 4rtmA-6bkaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPA_B_SAMB2304_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		5 / 12 GLY A 261
TRP A 264
HIS A 147
HIS A 197
GLN A 190
 FMN  A 401 (-3.3A)
None
FMN  A 401 (-3.4A)
None
FMN  A 401 (-3.9A)
 1.45A 4ypaB-6bkaA:
undetectable		 4ypaB-6bkaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		4 / 5 SER A 351
ASN A 200
GLN A 190
ASP A 205
 None
None
FMN  A 401 (-3.9A)
None
 1.30A 5kpcA-6bkaA:
undetectable		 5kpcA-6bkaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		5 / 12 PHE A  12
ILE A  41
ALA A 238
ILE A  19
PRO A  22
 None
None
FMN  A 401 ( 4.0A)
None
FMN  A 401 (-4.5A)
 1.31A 5mlmA-6bkaA:
2.0		 5mlmA-6bkaA:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		3 / 3 LYS A 116
LYS A 329
SER A 330
 None
 1.47A 5odiA-6bkaA:
undetectable		 5odiA-6bkaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		5 / 12 MET A 289
ALA A 292
GLY A 295
SER A 294
LEU A 298
 None
 1.46A 5vlmF-6bkaA:
undetectable		 5vlmF-6bkaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		5 / 12 HIS A 276
PHE A 280
GLY A 195
GLY A 261
ALA A  21
 None
None
FMN  A 401 (-3.7A)
FMN  A 401 (-3.3A)
FMN  A 401 (-3.6A)
 1.15A 6b3aA-6bkaA:
undetectable		 6b3aA-6bkaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 6bka NITRONATE
MONOOXYGENASE
(Cyberlindnera
mrakii) 		4 / 7 ALA A 291
GLY A 295
GLY A 199
ASN A 204
 None
 0.68A 6nm4A-6bkaA:
undetectable		 6nm4A-6bkaA:
undetectable