SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bkp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 6bkp HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 ALA A 113
PHE A  87
GLY A 116
GLU A  89
ARG A 269
 None
 1.35A 1cmcA-6bkpA:
undetectable
1cmcB-6bkpA:
undetectable		 1cmcA-6bkpA:
undetectable
1cmcB-6bkpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_B_SAMB105_0
(MET REPRESSOR)		 6bkp HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 GLU A  89
ARG A 269
ALA A 113
PHE A  87
GLY A 116
 None
 1.37A 1cmcA-6bkpA:
undetectable
1cmcB-6bkpA:
undetectable		 1cmcA-6bkpA:
undetectable
1cmcB-6bkpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 6bkp HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 194
THR A 155
LEU A 251
GLY A 249
 None
 0.81A 1gtiB-6bkpA:
undetectable		 1gtiB-6bkpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 6bkp HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 GLU A  89
ARG A 269
ALA A 113
PHE A  87
GLY A 116
 None
 1.40A 1mjqC-6bkpA:
undetectable
1mjqD-6bkpA:
undetectable		 1mjqC-6bkpA:
undetectable
1mjqD-6bkpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 6bkp HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.85A 4eq4A-6bkpA:
undetectable		 4eq4A-6bkpA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 6bkp HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.85A 4eqlA-6bkpA:
undetectable		 4eqlA-6bkpA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 6bkp HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.86A 4eqlB-6bkpA:
undetectable		 4eqlB-6bkpA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 6bkp HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.85A 4l39A-6bkpA:
undetectable		 4l39A-6bkpA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 6bkp HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 LEU A 194
TYR A 195
ILE A 252
GLY A 134
 None
 0.84A 4l39B-6bkpA:
undetectable		 4l39B-6bkpA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N6P_A_JMSA713_1
(LACTOTRANSFERRIN)		 6bkp HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 HIS A  18
ALA A  19
VAL A  20
GLU A  35
 None
 1.19A 4n6pA-6bkpA:
undetectable		 4n6pA-6bkpA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 6bkp HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 ILE A 217
PRO A 185
TYR A 233
VAL A 213
 None
 0.88A 4s0vA-6bkpA:
undetectable		 4s0vA-6bkpA:
10.20