SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6blb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 270
LEU A 291
ILE A 298
VAL A 282
PHE A 277
 None
 1.22A 1gx8A-6blbA:
undetectable		 1gx8A-6blbA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA799_1
(ADENOSINE KINASE)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		5 / 10 THR A 157
GLY A 108
VAL A 110
VAL A  82
ALA A  49
 None
 1.01A 1likA-6blbA:
undetectable		 1likA-6blbA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  61
LEU A  60
HIS A  58
ALA A  73
LEU A 119
 None
 1.29A 2a58A-6blbA:
undetectable
2a58B-6blbA:
undetectable		 2a58A-6blbA:
20.71
2a58B-6blbA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  61
LEU A  60
HIS A  58
ALA A  73
LEU A 119
 None
 1.28A 2a58B-6blbA:
undetectable
2a58C-6blbA:
undetectable		 2a58B-6blbA:
20.71
2a58C-6blbA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  61
LEU A  60
HIS A  58
ALA A  73
LEU A 119
 None
 1.28A 2a58D-6blbA:
undetectable
2a58E-6blbA:
undetectable		 2a58D-6blbA:
20.71
2a58E-6blbA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 300
THR A 220
PRO A 221
 None
None
ADP  A 401 (-4.4A)
 0.66A 2q64B-6blbA:
undetectable		 2q64B-6blbA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7P_A_SPMA501_1
(SPERMIDINE SYNTHASE)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		5 / 12 TYR A 311
HIS A 328
ASP A 258
GLN A 309
PRO A 304
 None
 1.22A 3b7pA-6blbA:
2.1		 3b7pA-6blbA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7P_B_SPMB502_1
(SPERMIDINE SYNTHASE)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		5 / 12 TYR A 311
HIS A 328
ASP A 258
GLN A 309
PRO A 304
 None
 1.23A 3b7pB-6blbA:
undetectable		 3b7pB-6blbA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		5 / 12 SER A  86
ILE A  84
ILE A  61
GLU A 115
GLY A  66
 None
None
None
None
ADP  A 401 (-3.4A)
 1.05A 3nxuA-6blbA:
undetectable		 3nxuA-6blbA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		4 / 7 VAL A  82
LEU A  56
MET A  42
ILE A  46
 None
 1.03A 3rfmA-6blbA:
undetectable		 3rfmA-6blbA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 300
THR A 220
PRO A 221
 None
None
ADP  A 401 (-4.4A)
 0.66A 3tkgD-6blbA:
undetectable		 3tkgD-6blbA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		4 / 6 ILE A 284
MET A 273
THR A 272
LEU A 269
 None
 0.99A 3wg7N-6blbA:
undetectable
3wg7W-6blbA:
undetectable		 3wg7N-6blbA:
21.43
3wg7W-6blbA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		4 / 8 GLU A 206
GLU A 212
LYS A 215
ARG A 216
 None
 0.83A 4bqfB-6blbA:
undetectable		 4bqfB-6blbA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 115
THR A 297
HIS A 296
 None
 0.87A 4q15A-6blbA:
undetectable		 4q15A-6blbA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  82
LEU A 127
MET A 131
 None
 0.81A 5ikrA-6blbA:
undetectable		 5ikrA-6blbA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 119
LEU A  98
LEU A 168
PRO A 129
ALA A 130
 None
 1.05A 5og9A-6blbA:
undetectable		 5og9A-6blbA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 119
VAL A 126
LEU A 168
PRO A 129
ALA A 130
 None
 1.28A 5og9A-6blbA:
undetectable		 5og9A-6blbA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 160
VAL A 179
SER A  88
HIS A 117
LEU A 119
 None
 1.19A 5ubbA-6blbA:
undetectable		 5ubbA-6blbA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		4 / 6 ILE A 284
MET A 273
THR A 272
LEU A 269
 None
 0.99A 5z86N-6blbA:
undetectable
5z86W-6blbA:
undetectable		 5z86N-6blbA:
21.43
5z86W-6blbA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		4 / 6 ILE A 284
MET A 273
THR A 272
LEU A 269
 None
 1.01A 5zcoN-6blbA:
undetectable
5zcoW-6blbA:
undetectable		 5zcoN-6blbA:
21.43
5zcoW-6blbA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 202
LEU A 201
VAL A 231
ALA A 235
LEU A 228
 None
 1.02A 6czmA-6blbA:
undetectable
6czmC-6blbA:
undetectable		 6czmA-6blbA:
24.94
6czmC-6blbA:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6blb HOLLIDAY JUNCTION
ATP-DEPENDENT DNA
HELICASE RUVB
(Pseudomonas
aeruginosa) 		4 / 7 ILE A  46
LEU A  56
THR A  71
LEU A  72
 None
None
ADP  A 401 (-3.7A)
None
 0.93A 6nmpA-6blbA:
undetectable
6nmpJ-6blbA:
undetectable		 6nmpA-6blbA:
21.43
6nmpJ-6blbA:
9.35