SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6blg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		4 / 6 GLU A 335
THR A 117
ALA A 115
LEU A 111
 None
 1.06A 1etb2-6blgA:
undetectable		 1etb2-6blgA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 130
VAL A 126
ASP A 152
ALA A 290
TYR A 321
 None
LLP  A 181 ( 4.9A)
LLP  A 181 ( 2.7A)
None
None
 1.32A 1kiaD-6blgA:
undetectable		 1kiaD-6blgA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		4 / 7 GLN A 255
GLU A 251
PHE A 177
ALA A 290
 None
 1.37A 1linA-6blgA:
undetectable		 1linA-6blgA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		4 / 7 THR A  80
THR A  84
VAL A 149
MET A 135
 None
LLP  A 181 ( 4.9A)
None
None
 1.19A 1tv8B-6blgA:
undetectable		 1tv8B-6blgA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_B_SAMB501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		4 / 7 THR A  80
THR A  84
VAL A 149
MET A 135
 None
LLP  A 181 ( 4.9A)
None
None
 1.20A 2fb2B-6blgA:
undetectable		 2fb2B-6blgA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A 173
THR A  46
ALA A 154
ALA A 191
PHE A 177
 None
None
LLP  A 181 ( 3.3A)
None
None
 0.80A 2gluB-6blgA:
2.5		 2gluB-6blgA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		5 / 9 PHE A 175
SER A  58
ALA A  49
LEU A 193
GLY A 173
 None
 1.43A 2wsfA-6blgA:
undetectable		 2wsfA-6blgA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		4 / 8 GLY A 156
GLY A 167
ILE A 169
SER A 159
 None
 0.68A 3d41A-6blgA:
undetectable		 3d41A-6blgA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  11
ALA A 245
ALA A 241
ALA A 240
SER A 236
 None
 0.94A 3sudA-6blgA:
undetectable		 3sudA-6blgA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		5 / 12 GLY A  11
ALA A 245
ALA A 241
ALA A 240
SER A 236
 None
 1.02A 3sudD-6blgA:
undetectable		 3sudD-6blgA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		5 / 12 ARG A 218
PHE A 217
PHE A 216
ARG A 213
GLU A 204
 None
 1.38A 4bvaA-6blgA:
3.0		 4bvaA-6blgA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		4 / 7 ILE A  68
ALA A  93
VAL A  89
ALA A 122
 None
 0.75A 4g77A-6blgA:
undetectable		 4g77A-6blgA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		5 / 10 LEU A 271
LEU A 372
ARG A 276
ILE A 277
THR A 366
 None
None
None
None
CL  A 410 (-3.6A)
 1.41A 4mk4A-6blgA:
undetectable		 4mk4A-6blgA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Q1S_A_AWYA1103_0
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		4 / 6 VAL A  74
LYS A  94
ILE A  68
LYS A 119
 None
 1.05A 5q1sA-6blgA:
2.0		 5q1sA-6blgA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		3 / 3 GLY A 156
LEU A 166
HIS A 127
 None
 0.68A 5u63A-6blgA:
undetectable		 5u63A-6blgA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		5 / 12 ILE A 194
LEU A  66
GLU A 151
ALA A 154
GLY A 156
 None
SO4  A 407 (-4.8A)
None
LLP  A 181 ( 3.3A)
None
 1.01A 5uxdB-6blgA:
undetectable		 5uxdB-6blgA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		5 / 12 ARG A 202
GLY A 170
ILE A  68
PHE A  88
GLY A 173
 None
SO4  A 403 ( 4.7A)
None
None
None
 1.03A 5veuH-6blgA:
undetectable		 5veuH-6blgA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		4 / 6 ILE A 123
LEU A  59
PHE A  88
PHE A 177
 None
 1.06A 5vkqA-6blgA:
undetectable
5vkqB-6blgA:
undetectable		 5vkqA-6blgA:
13.43
5vkqB-6blgA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		4 / 6 PHE A 177
ILE A 123
LEU A  59
PHE A  88
 None
 1.06A 5vkqA-6blgA:
undetectable
5vkqD-6blgA:
undetectable		 5vkqA-6blgA:
13.43
5vkqD-6blgA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		5 / 12 ALA A 154
GLU A  60
ILE A 172
VAL A 124
PHE A  88
 LLP  A 181 ( 3.3A)
None
None
None
None
 1.26A 5vlmG-6blgA:
undetectable		 5vlmG-6blgA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		5 / 9 VAL A 124
GLY A  92
VAL A  89
ASP A  72
GLY A  71
 None
SO4  A 406 ( 4.2A)
None
None
None
 1.36A 5zniA-6blgA:
undetectable		 5zniA-6blgA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		5 / 9 VAL A 131
HIS A 127
GLY A 130
ILE A 295
LEU A 279
 None
 1.46A 6c2mC-6blgA:
undetectable		 6c2mC-6blgA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		4 / 7 PHE A  88
LEU A  59
GLY A 173
LEU A 199
 None
 0.77A 6eu9D-6blgA:
undetectable		 6eu9D-6blgA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GZ9_A_TXCA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 6blg DTDP-4-AMINO-4,6-DID
EOXYGALACTOSE
TRANSAMINASE
(Klebsiella
pneumoniae) 		5 / 10 ASN A   5
ALA A   6
GLN A 246
PRO A   7
ASN A 289
 None
 1.35A 6gz9A-6blgA:
undetectable		 6gz9A-6blgA:
11.86