SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bm8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_SAMB293_0
(GLYCINE
N-METHYLTRANSFERASE)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 12 ALA A 390
SER A 388
ARG A 377
TYR A 429
TYR A 452
 None
 1.21A 1xvaB-6bm8A:
undetectable		 1xvaB-6bm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 10 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.90A 2f16K-6bm8A:
undetectable
2f16L-6bm8A:
undetectable		 2f16K-6bm8A:
15.09
2f16L-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 10 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.89A 2f16Y-6bm8A:
undetectable
2f16Z-6bm8A:
undetectable		 2f16Y-6bm8A:
15.09
2f16Z-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		3 / 3 ARG A 328
THR A 249
THR A 162
 None
 0.76A 3k2hB-6bm8A:
undetectable		 3k2hB-6bm8A:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 11 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.89A 3mg0K-6bm8A:
undetectable
3mg0L-6bm8A:
undetectable		 3mg0K-6bm8A:
15.09
3mg0L-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		3 / 3 TYR A 301
GLU A 286
TYR A 296
 None
 1.02A 3ug8A-6bm8A:
undetectable		 3ug8A-6bm8A:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		3 / 3 ASP A 608
ASP A 579
ASN A 112
 None
 0.76A 4q5mA-6bm8A:
undetectable		 4q5mA-6bm8A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 11 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.94A 4qvlK-6bm8A:
undetectable
4qvlL-6bm8A:
undetectable		 4qvlK-6bm8A:
15.09
4qvlL-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 11 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.94A 4qvlY-6bm8A:
undetectable
4qvlZ-6bm8A:
undetectable		 4qvlY-6bm8A:
15.09
4qvlZ-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 9 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.95A 4qvmK-6bm8A:
undetectable
4qvmL-6bm8A:
undetectable		 4qvmK-6bm8A:
15.57
4qvmL-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 10 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.96A 4qvmY-6bm8A:
undetectable
4qvmZ-6bm8A:
undetectable		 4qvmY-6bm8A:
15.57
4qvmZ-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 9 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.96A 4qvnK-6bm8A:
undetectable
4qvnL-6bm8A:
undetectable		 4qvnK-6bm8A:
16.67
4qvnL-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 9 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.96A 4qvnY-6bm8A:
undetectable
4qvnZ-6bm8A:
undetectable		 4qvnY-6bm8A:
16.67
4qvnZ-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 10 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.98A 4qvpK-6bm8A:
undetectable
4qvpL-6bm8A:
undetectable		 4qvpK-6bm8A:
15.09
4qvpL-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 10 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.97A 4qvpY-6bm8A:
undetectable
4qvpZ-6bm8A:
undetectable		 4qvpY-6bm8A:
15.09
4qvpZ-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 9 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.95A 4qvqK-6bm8A:
undetectable
4qvqL-6bm8A:
undetectable		 4qvqK-6bm8A:
15.09
4qvqL-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 9 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.95A 4qvqY-6bm8A:
undetectable
4qvqZ-6bm8A:
undetectable		 4qvqY-6bm8A:
15.09
4qvqZ-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 11 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.99A 4qw1K-6bm8A:
undetectable
4qw1L-6bm8A:
undetectable		 4qw1K-6bm8A:
15.09
4qw1L-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 10 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.98A 4qw1Y-6bm8A:
undetectable
4qw1Z-6bm8A:
undetectable		 4qw1Y-6bm8A:
15.09
4qw1Z-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 10 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.94A 4qw3K-6bm8A:
undetectable
4qw3L-6bm8A:
undetectable		 4qw3K-6bm8A:
15.09
4qw3L-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 10 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.94A 4qw3Y-6bm8A:
undetectable
4qw3Z-6bm8A:
undetectable		 4qw3Y-6bm8A:
15.09
4qw3Z-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		4 / 5 LEU A 330
ASP A 329
TYR A 164
THR A 162
 None
 1.12A 4wozF-6bm8A:
undetectable
4wozH-6bm8A:
undetectable		 4wozF-6bm8A:
undetectable
4wozH-6bm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 11 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.95A 5bxnK-6bm8A:
undetectable
5bxnL-6bm8A:
undetectable		 5bxnK-6bm8A:
15.09
5bxnL-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 11 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.94A 5bxnY-6bm8A:
undetectable
5bxnZ-6bm8A:
undetectable		 5bxnY-6bm8A:
15.09
5bxnZ-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 9 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.95A 5d0xK-6bm8A:
undetectable
5d0xL-6bm8A:
undetectable		 5d0xK-6bm8A:
15.09
5d0xL-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 9 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.94A 5d0xY-6bm8A:
undetectable
5d0xZ-6bm8A:
undetectable		 5d0xY-6bm8A:
15.09
5d0xZ-6bm8A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_1
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		4 / 4 ASP A 389
HIS A 433
SER A 457
GLU A 144
 None
 1.21A 5hfjG-6bm8A:
undetectable		 5hfjG-6bm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 9 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 1.02A 5l5zK-6bm8A:
undetectable
5l5zL-6bm8A:
undetectable		 5l5zK-6bm8A:
14.69
5l5zL-6bm8A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 9 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 1.01A 5l5zY-6bm8A:
undetectable
5l5zZ-6bm8A:
undetectable		 5l5zY-6bm8A:
14.69
5l5zZ-6bm8A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		3 / 3 VAL A 583
VAL A 602
GLN A 616
 None
 0.67A 5qh5A-6bm8A:
undetectable		 5qh5A-6bm8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 11 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.93A 6hwdK-6bm8A:
undetectable
6hwdL-6bm8A:
undetectable		 6hwdK-6bm8A:
18.07
6hwdL-6bm8A:
25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6bm8 ENVELOPE
GLYCOPROTEIN B
(Human
alphaherpesvirus
1) 		5 / 11 ALA A 211
THR A 221
ALA A 222
ALA A 190
ASP A 188
 None
 0.92A 6hwdY-6bm8A:
undetectable
6hwdZ-6bm8A:
undetectable		 6hwdY-6bm8A:
18.07
6hwdZ-6bm8A:
25.88