SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bma'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A  85
ILE A  67
LEU A  91
LEU A 115
LEU A 239
 None
 1.20A 1eiiA-6bmaA:
undetectable		 1eiiA-6bmaA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F86_B_T44B528_1
(TRANSTHYRETIN
THR119MET VARIANT)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		4 / 4 LYS A 176
LEU A 150
ALA A 177
LEU A 154
 None
 1.26A 1f86B-6bmaA:
undetectable		 1f86B-6bmaA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 11 ILE A 184
ALA A 182
LEU A 140
ALA A 177
ILE A  54
 None
 1.03A 2aclE-6bmaA:
undetectable		 2aclE-6bmaA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 11 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.87A 2aquB-6bmaA:
undetectable		 2aquB-6bmaA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 11 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.85A 2fxeB-6bmaA:
undetectable		 2fxeB-6bmaA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.88A 2hs1A-6bmaA:
undetectable		 2hs1A-6bmaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.83A 2nmyA-6bmaA:
undetectable		 2nmyA-6bmaA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_1
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.87A 2o4lA-6bmaA:
undetectable		 2o4lA-6bmaA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		4 / 5 LEU A  91
ALA A  60
ILE A  67
LYS A 118
 None
 1.04A 2othA-6bmaA:
undetectable		 2othA-6bmaA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.87A 3ekqA-6bmaA:
undetectable		 3ekqA-6bmaA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 10 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.87A 3ekwA-6bmaA:
undetectable		 3ekwA-6bmaA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.81A 3ekwB-6bmaA:
undetectable		 3ekwB-6bmaA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 11 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.87A 3em4A-6bmaA:
undetectable		 3em4A-6bmaA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 11 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.81A 3em4U-6bmaA:
undetectable		 3em4U-6bmaA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.84A 3jvyB-6bmaA:
undetectable		 3jvyB-6bmaA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.81A 3k4vD-6bmaA:
undetectable		 3k4vD-6bmaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		4 / 8 GLU A 129
PHE A 122
ARG A 117
ASP A 119
 None
 1.12A 3mjrD-6bmaA:
undetectable		 3mjrD-6bmaA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.79A 3nduA-6bmaA:
undetectable		 3nduA-6bmaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.80A 3nduD-6bmaA:
undetectable		 3nduD-6bmaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 9 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.81A 3ndwB-6bmaA:
undetectable		 3ndwB-6bmaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.79A 3ndxA-6bmaA:
undetectable		 3ndxA-6bmaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 11 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.81A 3ndxB-6bmaA:
undetectable		 3ndxB-6bmaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.83A 3oxcA-6bmaA:
undetectable		 3oxcA-6bmaA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.82A 3pwrA-6bmaA:
undetectable		 3pwrA-6bmaA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.84A 3tkgA-6bmaA:
undetectable		 3tkgA-6bmaA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.82A 3tkgC-6bmaA:
undetectable		 3tkgC-6bmaA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		4 / 4 SER A 105
ASP A 136
ASP A  24
ALA A  31
 None
None
PO4  A 306 (-3.2A)
None
 1.41A 3uj6A-6bmaA:
undetectable		 3uj6A-6bmaA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		4 / 4 LEU A  91
ALA A  60
ILE A  67
LYS A 118
 None
 1.10A 4eixA-6bmaA:
undetectable		 4eixA-6bmaA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		4 / 6 LEU A 139
ILE A 141
ALA A 142
ALA A 182
 None
 0.73A 4zf8A-6bmaA:
undetectable		 4zf8A-6bmaA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		4 / 8 ALA A 182
ASP A 170
ILE A 168
ILE A 187
 None
 0.88A 5t8sA-6bmaA:
undetectable		 5t8sA-6bmaA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ILE A 184
ALA A 182
LEU A 140
ALA A 177
ILE A  54
 None
 1.05A 6a60D-6bmaA:
undetectable		 6a60D-6bmaA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.86A 6dh6A-6bmaA:
undetectable		 6dh6A-6bmaA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		5 / 12 ALA A 237
ASP A 236
ILE A 184
GLY A 186
ILE A  54
 None
 0.84A 6difA-6bmaA:
undetectable		 6difA-6bmaA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_A_6J3A201_0
(TRANSTHYRETIN)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		4 / 4 LYS A 176
LEU A 150
ALA A 177
LEU A 154
 None
 1.31A 6gnrA-6bmaA:
undetectable		 6gnrA-6bmaA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNR_B_6J3B201_0
(TRANSTHYRETIN)		 6bma INDOLE-3-GLYCEROL
PHOSPHATE SYNTHASE
(Campylobacter
jejuni) 		4 / 4 LYS A 176
LEU A 150
ALA A 177
LEU A 154
 None
 1.29A 6gnrB-6bmaA:
undetectable		 6gnrB-6bmaA:
19.40