SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bme'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOX_A_THAA400_1 (HISTAMINE N-METHYLTRANSFERASE)	6bme	TRUNCATED HEMOGLOBIN 4 (Chlamydomonas reinhardtii)	4 / 8	PHE A 149 PHE A 114 TYR A 83 TYR A 91	HEM A 201 (-4.3A) HEM A 201 (-4.8A) HEM A 201 ( 4.9A) HEM A 201 ( 4.3A)	1.48A	2aoxA-6bmeA: 1.7	2aoxA-6bmeA: 16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM0_B_CHDB153_0 (ILEAL BILE ACID-BINDING PROTEIN)	6bme	TRUNCATED HEMOGLOBIN 4 (Chlamydomonas reinhardtii)	4 / 7	ILE A 135 PHE A 80 PHE A 51 GLY A 129	None HEM A 201 (-4.3A) None None	0.83A	3em0B-6bmeA: undetectable	3em0B-6bmeA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WRK_D_CAMD502_0 (CAMPHOR 5-MONOOXYGENASE)	6bme	TRUNCATED HEMOGLOBIN 4 (Chlamydomonas reinhardtii)	4 / 5	PHE A 121 LEU A 34 GLY A 86 VAL A 141	None	1.01A	3wrkD-6bmeA: undetectable	3wrkD-6bmeA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1Z_A_MXMA807_2 (PROSTAGLANDIN G/H SYNTHASE 1)	6bme	TRUNCATED HEMOGLOBIN 4 (Chlamydomonas reinhardtii)	5 / 6	VAL A 122 LEU A 125 LEU A 142 PHE A 65 MET A 56	None None HEM A 201 (-4.9A) HEM A 201 (-4.3A) None	1.50A	4o1zA-6bmeA: undetectable	4o1zA-6bmeA: 9.51

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2AOX_A_THAA400_1","HISTAMINE N-METHYLTRANSFERASE","6bme","TRUNCATED HEMOGLOBIN 4","Chlamydomonas reinhardtii",4,"PHE A 149;PHE A 114;TYR A  83;TYR A  91","HEM A 201 (-4.3A);HEM A 201 (-4.8A);HEM A 201 ( 4.9A);HEM A 201 ( 4.3A)","1.48A","2aoxA-6bmeA:1.7","2aoxA-6bmeA:16.82"],["3EM0_B_CHDB153_0","ILEAL BILE ACID-BINDING PROTEIN","6bme","TRUNCATED HEMOGLOBIN 4","Chlamydomonas reinhardtii",4,"ILE A 135;PHE A  80;PHE A  51;GLY A 129","None;HEM A 201 (-4.3A);None;None","0.83A","3em0B-6bmeA:undetectable","3em0B-6bmeA:undetectable"],["3WRK_D_CAMD502_0","CAMPHOR 5-MONOOXYGENASE","6bme","TRUNCATED HEMOGLOBIN 4","Chlamydomonas reinhardtii",4,"PHE A 121;LEU A  34;GLY A  86;VAL A 141","None","1.01A","3wrkD-6bmeA:undetectable","3wrkD-6bmeA:undetectable"],["4O1Z_A_MXMA807_2","PROSTAGLANDIN G\/H SYNTHASE 1","6bme","TRUNCATED HEMOGLOBIN 4","Chlamydomonas reinhardtii",5,"VAL A 122;LEU A 125;LEU A 142;PHE A  65;MET A  56","None;None;HEM A 201 (-4.9A);HEM A 201 (-4.3A);None","1.50A","4o1zA-6bmeA:undetectable","4o1zA-6bmeA:9.51"]]