SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bms'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		5 / 11 VAL A 150
GLY A 151
VAL A 136
ILE A  63
ALA A  62
 None
 0.91A 2yy8A-6bmsA:
undetectable
2yy8B-6bmsA:
undetectable		 2yy8A-6bmsA:
undetectable
2yy8B-6bmsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		4 / 7 TYR A  59
LEU A 214
PHE A 207
VAL A 203
 None
LMT  A1003 (-4.4A)
PLM  A1006 (-4.1A)
PLM  A1006 (-4.7A)
 1.14A 3jwqC-6bmsA:
undetectable		 3jwqC-6bmsA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		4 / 7 VAL A  19
TYR A  59
PHE A 207
LEU A 211
 PLM  A1006 ( 4.9A)
None
PLM  A1006 (-4.1A)
None
 0.99A 3qeoB-6bmsA:
undetectable		 3qeoB-6bmsA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		4 / 7 PHE A  64
THR A  65
ASN A 148
ILE A  63
 None
 0.98A 3t01A-6bmsA:
undetectable		 3t01A-6bmsA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		5 / 12 VAL A 257
SER A 272
SER A 153
SER A  68
HIS A 218
 None
 1.50A 3vt3A-6bmsA:
undetectable		 3vt3A-6bmsA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		5 / 12 VAL A 257
SER A 272
SER A 153
SER A  68
HIS A 218
 None
 1.49A 3vt7A-6bmsA:
undetectable		 3vt7A-6bmsA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		3 / 3 PRO A 102
LEU A 101
HIS A  75
 None
 0.60A 4pevA-6bmsA:
undetectable		 4pevA-6bmsA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RUJ_A_VDXA501_1
(VITAMIN D3 RECEPTOR
A)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		5 / 12 VAL A 257
SER A 272
SER A 153
SER A  68
HIS A 218
 None
 1.48A 4rujA-6bmsA:
undetectable		 4rujA-6bmsA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		5 / 10 GLY A 151
THR A 228
VAL A 150
HIS A 218
LEU A 221
 None
LMT  A1003 (-4.3A)
None
None
None
 1.25A 4yb6A-6bmsA:
undetectable
4yb6E-6bmsA:
undetectable		 4yb6A-6bmsA:
undetectable
4yb6E-6bmsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		5 / 10 GLY A 151
THR A 228
VAL A 150
HIS A 218
LEU A 221
 None
LMT  A1003 (-4.3A)
None
None
None
 1.26A 4yb6B-6bmsA:
undetectable
4yb6C-6bmsA:
undetectable		 4yb6B-6bmsA:
undetectable
4yb6C-6bmsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		5 / 10 GLY A 151
THR A 228
VAL A 150
HIS A 218
LEU A 221
 None
LMT  A1003 (-4.3A)
None
None
None
 1.25A 4yb6C-6bmsA:
undetectable
4yb6F-6bmsA:
undetectable		 4yb6C-6bmsA:
undetectable
4yb6F-6bmsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		5 / 10 GLY A 151
VAL A 150
THR A 228
HIS A 218
LEU A 221
 None
None
LMT  A1003 (-4.3A)
None
None
 1.36A 4yb6C-6bmsA:
undetectable
4yb6F-6bmsA:
undetectable		 4yb6C-6bmsA:
undetectable
4yb6F-6bmsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		5 / 10 HIS A 218
LEU A 221
GLY A 151
THR A 228
VAL A 150
 None
None
None
LMT  A1003 (-4.3A)
None
 1.26A 4yb6A-6bmsA:
undetectable
4yb6D-6bmsA:
undetectable		 4yb6A-6bmsA:
undetectable
4yb6D-6bmsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		5 / 10 HIS A 218
LEU A 221
GLY A 151
VAL A 150
THR A 228
 None
None
None
None
LMT  A1003 (-4.3A)
 1.34A 4yb6A-6bmsA:
undetectable
4yb6D-6bmsA:
undetectable		 4yb6A-6bmsA:
undetectable
4yb6D-6bmsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		5 / 10 HIS A 218
LEU A 221
GLY A 151
THR A 228
VAL A 150
 None
None
None
LMT  A1003 (-4.3A)
None
 1.26A 4yb6D-6bmsA:
undetectable
4yb6E-6bmsA:
undetectable		 4yb6D-6bmsA:
undetectable
4yb6E-6bmsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		5 / 10 HIS A 218
LEU A 221
GLY A 151
THR A 228
VAL A 150
 None
None
None
LMT  A1003 (-4.3A)
None
 1.26A 4yb6B-6bmsA:
undetectable
4yb6F-6bmsA:
undetectable		 4yb6B-6bmsA:
undetectable
4yb6F-6bmsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 6bms PALMITOYLTRANSFERASE
(Danio
rerio) 		4 / 5 HIS A 142
LEU A 137
TYR A 155
PHE A 158
 ZN  A1002 ( 3.1A)
None
None
PLM  A1006 (-4.7A)
 1.42A 5igjA-6bmsA:
2.0		 5igjA-6bmsA:
12.68