SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 6bn1 SCAFFOLD PROTEIN
SALVADOR
SERINE/THREONINE-PRO
TEIN KINASE HIPPO
(Drosophila
melanogaster) 		4 / 7 LEU B 563
ASP B 567
LEU B 570
MET A 650
 None
 0.86A 1n13G-6bn1B:
undetectable
1n13J-6bn1B:
undetectable		 1n13G-6bn1B:
22.08
1n13J-6bn1B:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 6bn1 SCAFFOLD PROTEIN
SALVADOR
SERINE/THREONINE-PRO
TEIN KINASE HIPPO
(Drosophila
melanogaster) 		4 / 7 LEU B 563
ASP B 567
LEU B 570
MET A 650
 None
 0.86A 1n13I-6bn1B:
undetectable
1n13L-6bn1B:
undetectable		 1n13I-6bn1B:
22.08
1n13L-6bn1B:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 6bn1 SCAFFOLD PROTEIN
SALVADOR
SERINE/THREONINE-PRO
TEIN KINASE HIPPO
(Drosophila
melanogaster) 		4 / 7 LEU B 563
ASP B 567
LEU B 570
MET A 650
 None
 0.87A 2qqcG-6bn1B:
undetectable
2qqcJ-6bn1B:
undetectable		 2qqcG-6bn1B:
21.79
2qqcJ-6bn1B:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 6bn1 SERINE/THREONINE-PRO
TEIN KINASE HIPPO
(Drosophila
melanogaster) 		4 / 5 ARG A 643
GLN A 644
PRO A 645
ILE A 646
 MPD  A 703 ( 3.7A)
MPD  A 703 (-4.1A)
None
None
 1.33A 5ki6A-6bn1A:
undetectable		 5ki6A-6bn1A:
undetectable