SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bnf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		4 / 7 ARG A 436
ASP A 438
ASP A 439
TYR A 395
 SO4  A 603 (-2.9A)
None
None
None
 1.47A 1cebA-6bnfA:
undetectable		 1cebA-6bnfA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		4 / 8 TYR A 433
GLU A 273
HIS A 549
SER A 318
 None
ZN  A 602 (-2.3A)
None
None
 1.23A 1nx9A-6bnfA:
undetectable		 1nx9A-6bnfA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		4 / 8 TYR A 433
GLU A 273
HIS A 549
SER A 318
 None
ZN  A 602 (-2.3A)
None
None
 1.23A 1nx9B-6bnfA:
undetectable		 1nx9B-6bnfA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		4 / 8 TYR A 433
GLU A 273
HIS A 549
SER A 318
 None
ZN  A 602 (-2.3A)
None
None
 1.25A 1nx9C-6bnfA:
undetectable		 1nx9C-6bnfA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		4 / 8 TYR A 433
GLU A 273
HIS A 549
SER A 318
 None
ZN  A 602 (-2.3A)
None
None
 1.25A 1nx9D-6bnfA:
undetectable		 1nx9D-6bnfA:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		4 / 5 TRP A 530
ILE A 480
LEU A 529
ALA A 492
 None
 1.20A 1xvaA-6bnfA:
2.3
1xvaB-6bnfA:
undetectable		 1xvaA-6bnfA:
undetectable
1xvaB-6bnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		4 / 4 GLY A 312
SER A 318
ILE A 525
HIS A 549
 GOL  A 610 ( 3.8A)
None
None
None
 1.06A 1yajJ-6bnfA:
undetectable		 1yajJ-6bnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		3 / 3 ASP A 418
ASP A 490
ASN A 416
 None
 0.85A 2bm9D-6bnfA:
undetectable		 2bm9D-6bnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		4 / 6 SER A 360
VAL A 271
ASP A 357
TRP A 355
 ACT  A 609 ( 4.7A)
None
None
None
 1.43A 2x45A-6bnfA:
undetectable		 2x45A-6bnfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		4 / 6 SER A 360
VAL A 319
ASP A 357
TRP A 355
 ACT  A 609 ( 4.7A)
None
None
None
 1.46A 2x45A-6bnfA:
undetectable		 2x45A-6bnfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		3 / 3 GLY A 272
TYR A 495
SER A 497
 None
 0.75A 2xatA-6bnfA:
undetectable		 2xatA-6bnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		4 / 8 THR A 335
TYR A 338
ILE A 247
ASP A 332
 None
 1.09A 2xytE-6bnfA:
undetectable		 2xytE-6bnfA:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM7_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		4 / 7 ALA A 275
TYR A 495
ILE A 525
HIS A 549
 None
 0.63A 2zm7A-6bnfA:
undetectable		 2zm7A-6bnfA:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT2_A_ASDA1490_1
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		5 / 10 GLU A 501
ALA A 277
PHE A 290
TYR A 495
SER A 497
 None
 1.48A 4at2A-6bnfA:
0.0		 4at2A-6bnfA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		5 / 12 PHE A 560
GLN A 373
LEU A 369
ILE A 343
LEU A 556
 None
 1.37A 4k38B-6bnfA:
undetectable		 4k38B-6bnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		5 / 12 PHE A 560
GLN A 373
LEU A 369
ILE A 343
LEU A 556
 None
 1.26A 4k39A-6bnfA:
undetectable		 4k39A-6bnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMU_C_RFPC1401_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		5 / 12 GLN A 373
GLN A 375
ASP A 406
ARG A 356
ILE A 421
 None
 1.48A 4kmuC-6bnfA:
undetectable		 4kmuC-6bnfA:
4.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		4 / 7 TYR A 433
GLU A 501
GLU A 521
GLU A 505
 None
 1.18A 4mi4A-6bnfA:
undetectable
4mi4C-6bnfA:
undetectable		 4mi4A-6bnfA:
16.83
4mi4C-6bnfA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		4 / 5 ILE A 421
VAL A 268
PHE A 573
HIS A 414
 None
 1.35A 4rzvA-6bnfA:
undetectable		 4rzvA-6bnfA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		5 / 6 GLY A 312
THR A 313
SER A 314
TYR A 317
GLY A 512
 GOL  A 610 ( 3.8A)
GOL  A 610 (-3.8A)
PO4  A 601 (-3.9A)
GOL  A 610 (-4.0A)
None
 0.16A 5k4pA-6bnfA:
52.6		 5k4pA-6bnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 6bnf PHOSPHOETHANOLAMINE
TRANSFERASE
(Moraxella
sp.
HMSC061H09) 		5 / 12 ILE A 343
PHE A 560
VAL A 351
VAL A 267
TYR A 331
 None
 1.10A 6djzA-6bnfA:
undetectable		 6djzA-6bnfA:
undetectable