SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bng'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		4 / 6 VAL A  24
VAL A  94
ILE A  97
ARG A  11
 None
 1.15A 1iepA-6bngA:
undetectable		 1iepA-6bngA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		5 / 10 ASP A 201
ASN A 140
ILE A 115
GLU A 241
GLY A  28
 None
 1.21A 1mehA-6bngA:
5.6		 1mehA-6bngA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		4 / 8 ASP A 201
ASN A 140
ILE A 115
GLY A  28
 None
 0.99A 1meiA-6bngA:
7.3		 1meiA-6bngA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		3 / 3 THR A 126
GLU A 161
HIS A 154
 None
 0.91A 1xwfB-6bngA:
undetectable		 1xwfB-6bngA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		3 / 3 THR A 126
GLU A 161
HIS A 154
 None
 0.91A 1xwfC-6bngA:
undetectable		 1xwfC-6bngA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		3 / 3 THR A 126
GLU A 161
HIS A 154
 None
 0.90A 1xwfD-6bngA:
undetectable		 1xwfD-6bngA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		5 / 12 ILE A  41
GLY A  28
LEU A 238
VAL A  24
ILE A  54
 None
 1.19A 1zq9A-6bngA:
undetectable		 1zq9A-6bngA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		5 / 12 PRO A 209
GLY A 210
ASN A 179
ASP A 252
ASP A 247
 None
 1.38A 2b9eA-6bngA:
undetectable		 2b9eA-6bngA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		3 / 3 PRO A 197
PHE A 188
LYS A 192
 None
 1.26A 3bjwG-6bngA:
undetectable		 3bjwG-6bngA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		5 / 12 GLY A  27
VAL A  57
MET A 231
CYH A 170
ILE A 115
 None
 1.18A 3h52B-6bngA:
undetectable		 3h52B-6bngA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		5 / 12 GLY A  28
LEU A 269
MET A 231
CYH A 170
ILE A  97
 None
 1.24A 3h52B-6bngA:
undetectable		 3h52B-6bngA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		4 / 6 MET A  17
VAL A  24
ILE A 115
LEU A 238
 None
 0.80A 3hegA-6bngA:
undetectable		 3hegA-6bngA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQZ_A_LQZA586_1
(SERUM ALBUMIN)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		4 / 6 ARG A 172
ASP A 201
LYS A 142
LYS A  59
 SO4  A 301 (-4.0A)
None
SO4  A 301 (-2.7A)
None
 1.40A 3jqzA-6bngA:
0.6		 3jqzA-6bngA:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		4 / 6 SER A  61
GLN A 117
PHE A 239
HIS A 204
 None
SO4  A 301 ( 4.9A)
None
None
 1.41A 3lskB-6bngA:
undetectable		 3lskB-6bngA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		4 / 6 SER A  61
GLN A 117
PHE A 239
HIS A 204
 None
SO4  A 301 ( 4.9A)
None
None
 1.41A 3lskD-6bngA:
undetectable		 3lskD-6bngA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		5 / 11 TYR A  56
VAL A  94
ILE A 115
ALA A  60
THR A  98
 None
 1.12A 3mdtB-6bngA:
undetectable		 3mdtB-6bngA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		5 / 12 TYR A  45
LEU A  25
GLY A  27
SER A 242
LEU A  52
 None
 1.10A 3okxB-6bngA:
undetectable		 3okxB-6bngA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		5 / 12 ILE A  88
GLY A  81
ILE A  82
ILE A 115
ALA A 137
 None
 0.99A 5e72A-6bngA:
undetectable		 5e72A-6bngA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		5 / 12 VAL A  10
ALA A 236
PHE A  26
ASN A 140
VAL A  57
 None
 1.49A 6drxA-6bngA:
undetectable		 6drxA-6bngA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		4 / 5 ARG A  67
ARG A  74
GLY A  75
ASP A  63
 SO4  A 300 (-4.0A)
None
None
None
 1.34A 6dwjB-6bngA:
undetectable
6dwjD-6bngA:
undetectable		 6dwjB-6bngA:
undetectable
6dwjD-6bngA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_1
(-)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		5 / 12 GLU A 171
LEU A 206
LEU A 226
MET A 185
PHE A 188
 None
 1.49A 6f3nA-6bngA:
undetectable		 6f3nA-6bngA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_1
(-)		 6bng 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE
(Acinetobacter
baumannii) 		5 / 12 GLU A 171
LEU A 206
LEU A 226
MET A 185
PHE A 188
 None
 1.50A 6f3nD-6bngA:
undetectable		 6f3nD-6bngA:
10.85