SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bni'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		4 / 6 LEU A 333
LEU A 524
PRO A 429
VAL A 460
 None
 1.10A 2dqyC-6bniA:
undetectable		 2dqyC-6bniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		4 / 7 ILE A 433
ARG A 365
ASP A 324
GLU A 327
 None
 1.09A 2qebA-6bniA:
undetectable		 2qebA-6bniA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		4 / 6 ARG A 107
ASP A 117
ILE A 118
LEU A  76
 None
 0.74A 2ya7A-6bniA:
undetectable		 2ya7A-6bniA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		4 / 6 ARG A 107
ASP A 117
ILE A 118
LEU A  76
 None
 0.73A 2ya7B-6bniA:
undetectable		 2ya7B-6bniA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		4 / 6 ARG A 107
ASP A 117
ILE A 118
LEU A  76
 None
 0.73A 2ya7D-6bniA:
undetectable		 2ya7D-6bniA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		5 / 12 PHE A 456
PHE A 230
PHE A 235
LEU A 233
ALA A 317
 None
 1.31A 3apvB-6bniA:
undetectable		 3apvB-6bniA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		5 / 12 PHE A 368
ILE A 372
PRO A 436
LEU A 414
TYR A 320
 None
 1.14A 3eeoA-6bniA:
undetectable		 3eeoA-6bniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		5 / 11 PHE A  70
LEU A  76
SER A  98
PHE A 156
ILE A 118
 None
 1.28A 3ko0A-6bniA:
undetectable
3ko0B-6bniA:
1.7
3ko0I-6bniA:
undetectable
3ko0J-6bniA:
1.6		 3ko0A-6bniA:
18.52
3ko0B-6bniA:
18.52
3ko0I-6bniA:
18.52
3ko0J-6bniA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		6 / 11 ILE A 114
ILE A 118
SER A 100
ALA A 129
VAL A 154
GLY A 155
 None
 1.35A 3kw4A-6bniA:
undetectable		 3kw4A-6bniA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		4 / 8 TYR A 345
ILE A 357
ILE A 343
VAL A 460
 None
 0.71A 3p4wC-6bniA:
undetectable		 3p4wC-6bniA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_B_GLYB511_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		4 / 5 GLU A 474
LEU A 476
GLN A 477
LYS A 480
 None
 1.41A 3pgyB-6bniA:
1.7		 3pgyB-6bniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		5 / 10 LEU A 519
ALA A 222
ILE A 330
TRP A 517
PHE A 230
 None
 1.37A 3qpsA-6bniA:
undetectable		 3qpsA-6bniA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		4 / 5 GLY A 349
PRO A 347
ASN A 532
TYR A 345
 None
 0.94A 3u8qA-6bniA:
undetectable		 3u8qA-6bniA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_B_ZPCB1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		5 / 12 ARG A 523
ILE A 534
GLU A 495
GLU A 423
GLU A 457
 ADN  A 602 (-3.6A)
None
None
None
None
 1.35A 4a97A-6bniA:
undetectable
4a97B-6bniA:
undetectable		 4a97A-6bniA:
13.68
4a97B-6bniA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_G_ZPCG1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6bni LYSINE--TRNA LIGASE
(Cryptosporidium
parvum) 		5 / 12 ARG A 523
ILE A 534
GLU A 495
GLU A 423
GLU A 457
 ADN  A 602 (-3.6A)
None
None
None
None
 1.38A 4a97F-6bniA:
0.0
4a97G-6bniA:
1.2		 4a97F-6bniA:
13.68
4a97G-6bniA:
13.68