SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bnl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 6bnl NKT VALPHA14 (MOUSE)
- 2C12 TCR - HYBRID
MOUSE VARIABLE AND
HUMAN CONSTANT
DOMAINS
(Homo
sapiens) 		5 / 11 LEU C 112
GLU C  16
VAL C  12
LEU C  46
LEU C  75
 None
 1.35A 1mrqA-6bnlC:
undetectable		 1mrqA-6bnlC:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 6bnl NKT VALPHA14 (MOUSE)
- 2C12 TCR - HYBRID
MOUSE VARIABLE AND
HUMAN CONSTANT
DOMAINS
(Homo
sapiens) 		4 / 5 LEU C  20
GLN C 111
THR C 110
THR C  80
 None
 0.94A 2zj0B-6bnlC:
undetectable		 2zj0B-6bnlC:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 6bnl NKT VALPHA14 (MOUSE)
- 2C12 TCR - HYBRID
MOUSE VARIABLE AND
HUMAN CONSTANT
DOMAINS
(Homo
sapiens) 		3 / 3 PRO C 116
LEU C  82
ARG C 169
 None
 0.86A 3aqiB-6bnlC:
undetectable		 3aqiB-6bnlC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 6bnl NKT VALPHA14 (MOUSE)
- 2C12 TCR - HYBRID
MOUSE VARIABLE AND
HUMAN CONSTANT
DOMAINS
(Homo
sapiens) 		4 / 7 TYR C  24
LEU C  66
ASP C  67
LYS C  71
 None
 1.40A 3lslA-6bnlC:
undetectable
3lslD-6bnlC:
undetectable		 3lslA-6bnlC:
undetectable
3lslD-6bnlC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID800_0
(GLUTAMATE RECEPTOR 2)		 6bnl NKT VALPHA14 (MOUSE)
- 2C12 TCR - HYBRID
MOUSE VARIABLE AND
HUMAN CONSTANT
DOMAINS
(Homo
sapiens) 		4 / 7 TYR C  24
LEU C  66
ASP C  67
LYS C  71
 None
 1.45A 3lslA-6bnlC:
undetectable
3lslD-6bnlC:
undetectable		 3lslA-6bnlC:
undetectable
3lslD-6bnlC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 6bnl NKT VALPHA14 (MOUSE)
- 2C12 TCR - HYBRID
MOUSE VARIABLE AND
HUMAN CONSTANT
DOMAINS
(Homo
sapiens) 		4 / 6 TYR C  24
LEU C  66
ASP C  67
LYS C  71
 None
 1.46A 3lslG-6bnlC:
undetectable		 3lslG-6bnlC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 6bnl NKT VALPHA14 (MOUSE)
- 2C12 TCR - HYBRID
MOUSE VARIABLE AND
HUMAN CONSTANT
DOMAINS
(Homo
sapiens) 		3 / 3 GLN C   2
THR C   1
LEU C  32
 None
 0.70A 3ondA-6bnlC:
undetectable		 3ondA-6bnlC:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 6bnl NKT VALPHA14 (MOUSE)
- 2C12 TCR - HYBRID
MOUSE VARIABLE AND
HUMAN CONSTANT
DOMAINS
(Homo
sapiens) 		3 / 3 GLN C   2
THR C   1
LEU C  32
 None
 0.72A 3ondB-6bnlC:
undetectable		 3ondB-6bnlC:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 6bnl NKT VALPHA14 (MOUSE)
- 2C12 TCR - HYBRID
MOUSE VARIABLE AND
HUMAN CONSTANT
DOMAINS
(Homo
sapiens) 		3 / 3 TYR C  88
ASP C  38
ASP C  84
 None
 0.85A 5x6yA-6bnlC:
undetectable		 5x6yA-6bnlC:
undetectable