SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bnp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 12 LEU I 251
LEU I 265
ALA I 342
LEU I 378
ILE I 259
 None
 1.11A 1crbA-6bnpI:
undetectable		 1crbA-6bnpI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		4 / 6 GLN I 145
ARG I 487
PHE I 483
PHE I 209
 None
 1.42A 1e73M-6bnpI:
undetectable		 1e73M-6bnpI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HO5_A_ADNA1604_1
(5'-NUCLEOTIDASE)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 11 ILE I 178
GLY I 173
PHE I 214
ASN I 215
GLY I 175
 None
 1.43A 1ho5A-6bnpI:
undetectable		 1ho5A-6bnpI:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 10 VAL I  90
MET I 701
LEU I  68
GLN I 481
PHE I 484
 None
 1.25A 1rlbE-6bnpI:
undetectable		 1rlbE-6bnpI:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 12 LEU I 263
LEU I 251
ILE I 247
ALA I 424
LEU I 379
 None
 0.99A 2h42C-6bnpI:
undetectable		 2h42C-6bnpI:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		4 / 8 ILE I 247
PHE I 432
TYR I 428
GLY I 193
 None
 0.90A 2vdbA-6bnpI:
undetectable		 2vdbA-6bnpI:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		3 / 3 GLU I 575
HIS I 465
GLU I 589
 None
 0.67A 2x45B-6bnpI:
undetectable		 2x45B-6bnpI:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		3 / 3 GLU I 575
HIS I 465
GLU I 589
 None
 0.65A 2x45C-6bnpI:
undetectable		 2x45C-6bnpI:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		4 / 8 THR I 197
GLN I 470
TYR I 462
SER I 153
 None
 1.20A 2xz5C-6bnpI:
undetectable
2xz5D-6bnpI:
undetectable		 2xz5C-6bnpI:
undetectable
2xz5D-6bnpI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 11 PHE I 593
LEU I 526
ILE I 525
PHE I 577
PHE I 543
 None
 1.41A 3a9eB-6bnpI:
undetectable		 3a9eB-6bnpI:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		4 / 5 VAL I 221
VAL I 220
PHE I 224
ARG I 166
 None
 1.34A 3bjwH-6bnpI:
0.2		 3bjwH-6bnpI:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		4 / 7 LEU I 306
PRO I 268
SER I 297
GLY I 277
 None
 1.06A 3hcnA-6bnpI:
undetectable		 3hcnA-6bnpI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		4 / 7 LEU I 306
PRO I 268
SER I 297
GLY I 277
 None
 1.00A 3hcrB-6bnpI:
undetectable		 3hcrB-6bnpI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		4 / 7 VAL I 506
TYR I 496
LYS I 490
GLU I 494
 None
 1.30A 3hs4A-6bnpI:
undetectable		 3hs4A-6bnpI:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 12 LEU I 251
SER I 256
CYH I 321
VAL I 341
LEU I 378
 None
 1.29A 3m7rA-6bnpI:
undetectable		 3m7rA-6bnpI:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		4 / 7 PHE I 206
SER I 226
VAL I 210
VAL I 436
 None
 1.12A 3n61A-6bnpI:
undetectable
3n61B-6bnpI:
undetectable		 3n61A-6bnpI:
14.51
3n61B-6bnpI:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		4 / 8 PHE I 206
SER I 226
VAL I 210
VAL I 436
 None
 1.12A 3nlrA-6bnpI:
undetectable
3nlrB-6bnpI:
undetectable		 3nlrA-6bnpI:
14.51
3nlrB-6bnpI:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 12 ILE I 147
SER I 146
GLY I 453
SER I 144
THR I 661
 None
 1.35A 3r75A-6bnpI:
undetectable		 3r75A-6bnpI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 12 ILE I 147
SER I 146
GLY I 453
SER I 144
THR I 661
 None
 1.36A 3r75B-6bnpI:
undetectable		 3r75B-6bnpI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		3 / 3 GLN I 592
GLU I 469
LYS I 596
 None
 1.15A 3su9A-6bnpI:
undetectable		 3su9A-6bnpI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 12 ILE I 518
GLY I 524
ASP I 527
VAL I 643
TYR I 475
 None
 1.21A 4a81A-6bnpI:
undetectable		 4a81A-6bnpI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJL_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 12 ILE I 528
ILE I 579
ARG I 580
LEU I 517
ILE I 525
 None
 0.99A 4kjlA-6bnpI:
undetectable		 4kjlA-6bnpI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 11 PHE I 271
ALA I 376
LEU I 378
GLU I 377
GLN I 370
 None
 1.19A 4l8fD-6bnpI:
undetectable		 4l8fD-6bnpI:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 10 LEU I 292
ALA I 253
GLY I 315
ILE I 318
ILE I 291
 None
 1.07A 4njuB-6bnpI:
undetectable		 4njuB-6bnpI:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 10 LEU I 292
ALA I 253
GLY I 315
ILE I 318
ILE I 291
 None
 1.08A 4njuD-6bnpI:
undetectable		 4njuD-6bnpI:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_A_NOVA2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 11 ASN I  62
ASP I  61
GLU I  60
ASP I  58
ILE I  95
 None
 1.46A 4urnA-6bnpI:
undetectable		 4urnA-6bnpI:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_B_NOVB2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 11 ASN I  62
ASP I  61
GLU I  60
ASP I  58
ILE I  95
 None
 1.46A 4urnB-6bnpI:
undetectable		 4urnB-6bnpI:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_C_NOVC2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 11 ASN I  62
ASP I  61
GLU I  60
ASP I  58
ILE I  95
 None
 1.48A 4urnC-6bnpI:
undetectable		 4urnC-6bnpI:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		4 / 6 ILE I 571
HIS I 581
ILE I 525
VAL I 547
 None
 0.93A 4zj8A-6bnpI:
undetectable		 4zj8A-6bnpI:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		3 / 3 TYR I 450
LYS I 142
LYS I 139
 None
 0.81A 5dbyA-6bnpI:
undetectable		 5dbyA-6bnpI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 12 ALA I 422
PHE I 577
ILE I 579
PHE I 543
PHE I 647
 None
 1.19A 5fsaA-6bnpI:
undetectable		 5fsaA-6bnpI:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		4 / 8 PHE I 484
ILE I 488
LEU I  73
LEU I  68
 None
 0.73A 5hs1A-6bnpI:
undetectable		 5hs1A-6bnpI:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 12 ALA I 422
PHE I 577
ILE I 579
PHE I 543
PHE I 647
 None
 1.17A 5jlcA-6bnpI:
undetectable		 5jlcA-6bnpI:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		4 / 7 GLN I 512
ASP I 516
HIS I 551
TYR I 588
 None
 1.40A 5ov9B-6bnpI:
undetectable		 5ov9B-6bnpI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 12 PHE I 577
ILE I 579
PHE I 543
PHE I 468
PHE I 647
 None
 1.23A 5v5zA-6bnpI:
undetectable		 5v5zA-6bnpI:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		3 / 3 GLU I 332
LEU I 335
ARG I 339
 None
 0.81A 6d8fA-6bnpI:
undetectable		 6d8fA-6bnpI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 6bnp UNCONVENTIONAL
MYOSIN-VI
(Sus
scrofa) 		5 / 10 LEU I 390
LEU I 601
ASP I 599
ILE I 350
GLY I 348
 None
 1.01A 6dm0B-6bnpI:
undetectable
6dm0C-6bnpI:
undetectable		 6dm0B-6bnpI:
19.10
6dm0C-6bnpI:
19.10