SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bo6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 6bo6 -
(-) 		4 / 5 THR A  91
THR A 180
GLU A 310
THR A 341
 None
 1.43A 1d4fB-6bo6A:
undetectable		 1d4fB-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_1
(VITAMIN D NUCLEAR
RECEPTOR)		 6bo6 -
(-) 		5 / 12 LEU A 508
SER A 473
SER A 458
SER A 428
LEU A 502
 None
 1.33A 1db1A-6bo6A:
undetectable		 1db1A-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F9G_A_ASCA950_0
(HYALURONATE LYASE)		 6bo6 -
(-) 		4 / 7 ARG A 340
TYR A 485
ARG A 574
ASN A 578
 None
E0V  A 701 (-4.4A)
E0V  A 701 (-3.8A)
E0V  A 701 (-3.0A)
 1.24A 1f9gA-6bo6A:
undetectable		 1f9gA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 6bo6 -
(-) 		3 / 3 ALA A 415
VAL A 417
TRP A 420
 None
 0.83A 1micA-6bo6A:
undetectable
1micB-6bo6A:
undetectable		 1micA-6bo6A:
undetectable
1micB-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bo6 -
(-) 		4 / 8 SER A 569
ASN A 148
GLN A 166
ASP A  61
 None
 1.34A 1p6kA-6bo6A:
undetectable		 1p6kA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bo6 -
(-) 		4 / 8 SER A 569
ASN A 148
GLN A 166
ASP A  61
 None
 1.34A 1rs6A-6bo6A:
undetectable		 1rs6A-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bo6 -
(-) 		4 / 8 SER A 569
ASN A 148
GLN A 166
ASP A  61
 None
 1.34A 1rs6B-6bo6A:
undetectable		 1rs6B-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_B_BEZB882_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 6bo6 -
(-) 		5 / 12 GLY A 307
TYR A 346
ILE A 362
ARG A 340
HIS A 343
 None
None
None
None
E0V  A 701 (-3.9A)
 1.32A 1tmxB-6bo6A:
undetectable		 1tmxB-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 6bo6 -
(-) 		4 / 6 THR A  91
PHE A 110
PHE A 171
ASN A 175
 None
 1.16A 1tt0A-6bo6A:
0.5		 1tt0A-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 6bo6 -
(-) 		4 / 6 THR A  91
PHE A 110
PHE A 171
ASN A 175
 None
 1.19A 1tt0B-6bo6A:
0.0		 1tt0B-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 6bo6 -
(-) 		4 / 6 THR A  91
PHE A 110
PHE A 171
ASN A 175
 None
 1.14A 1tt0C-6bo6A:
undetectable		 1tt0C-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 6bo6 -
(-) 		4 / 6 THR A  91
PHE A 110
PHE A 171
ASN A 175
 None
 1.16A 1tt0D-6bo6A:
undetectable		 1tt0D-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 6bo6 -
(-) 		5 / 12 ARG A 340
GLU A 516
PHE A 173
ASN A 479
VAL A 459
 None
E0V  A 701 (-2.6A)
None
E0V  A 701 ( 4.7A)
None
 1.40A 1x70A-6bo6A:
undetectable		 1x70A-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZWP_A_NIMA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 6bo6 -
(-) 		4 / 5 LEU A 582
GLY A 518
TRP A 561
ASP A 520
 None
None
E0V  A 701 (-3.9A)
None
 1.39A 1zwpA-6bo6A:
undetectable		 1zwpA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bo6 -
(-) 		4 / 8 SER A 569
ASN A 148
GLN A 166
ASP A  61
 None
 1.31A 1zzqA-6bo6A:
undetectable		 1zzqA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6bo6 -
(-) 		4 / 8 SER A 569
ASN A 148
GLN A 166
ASP A  61
 None
 1.30A 1zzqB-6bo6A:
undetectable		 1zzqB-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 6bo6 -
(-) 		4 / 7 PHE A 437
TYR A 436
THR A 396
GLY A 369
 None
 0.92A 2a1mA-6bo6A:
undetectable		 2a1mA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 6bo6 -
(-) 		4 / 4 LEU A 440
PRO A 439
LEU A 443
ARG A 405
 None
 1.29A 2hrcA-6bo6A:
undetectable		 2hrcA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6bo6 -
(-) 		4 / 4 LEU A 440
PRO A 439
LEU A 443
ARG A 405
 None
 1.37A 2pnjB-6bo6A:
undetectable		 2pnjB-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 6bo6 -
(-) 		5 / 11 ASN A 424
GLU A 425
TYR A 481
GLU A 516
TRP A 561
 E0V  A 701 (-3.3A)
E0V  A 701 (-2.6A)
E0V  A 701 (-4.4A)
E0V  A 701 (-2.6A)
E0V  A 701 (-3.9A)
 0.72A 2v3dB-6bo6A:
15.1		 2v3dB-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 6bo6 -
(-) 		5 / 11 THR A 455
VAL A 289
VAL A 418
ARG A 288
ILE A 296
 None
 0.93A 2zbzA-6bo6A:
undetectable		 2zbzA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 6bo6 -
(-) 		4 / 8 ALA A  48
TYR A  68
ILE A 179
HIS A  92
 None
 0.84A 2zm8A-6bo6A:
undetectable		 2zm8A-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 6bo6 -
(-) 		4 / 8 ALA A  48
TYR A  68
ILE A 179
HIS A  92
 None
 0.84A 2zmaA-6bo6A:
undetectable		 2zmaA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 6bo6 -
(-) 		3 / 3 THR A 180
GLU A 310
HIS A 309
 None
 0.77A 3g1uB-6bo6A:
undetectable		 3g1uB-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6bo6 -
(-) 		4 / 8 ARG A 587
PRO A 182
SER A  16
GLY A 318
 None
 1.11A 3hcrA-6bo6A:
undetectable		 3hcrA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 6bo6 -
(-) 		5 / 12 ASN A 424
VAL A 457
GLY A 307
ASN A 562
ARG A 587
 E0V  A 701 (-3.3A)
None
None
None
None
 0.88A 3k13B-6bo6A:
6.9		 3k13B-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_G_P77G203_1
(PROTEIN S100-A4)		 6bo6 -
(-) 		5 / 9 ASP A 363
PHE A 339
ILE A 328
LEU A 353
ASP A 355
 None
 1.42A 3m0wG-6bo6A:
undetectable
3m0wH-6bo6A:
undetectable
3m0wI-6bo6A:
undetectable
3m0wJ-6bo6A:
undetectable		 3m0wG-6bo6A:
undetectable
3m0wH-6bo6A:
undetectable
3m0wI-6bo6A:
undetectable
3m0wJ-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6bo6 -
(-) 		4 / 5 VAL A 403
LEU A 407
ILE A 422
ALA A 367
 None
 0.98A 3n8yB-6bo6A:
undetectable		 3n8yB-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 6bo6 -
(-) 		4 / 6 THR A 462
SER A 473
ILE A 422
THR A 466
 None
 1.04A 3q70A-6bo6A:
undetectable		 3q70A-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 6bo6 -
(-) 		4 / 5 PRO A 453
ILE A 359
TRP A 259
PHE A 294
 None
 1.21A 3topB-6bo6A:
9.0		 3topB-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 6bo6 -
(-) 		4 / 6 THR A 312
ASN A 320
ASP A 327
ILE A 330
 None
 1.43A 3w9tB-6bo6A:
undetectable		 3w9tB-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 6bo6 -
(-) 		3 / 3 ASN A 133
TRP A  65
ASP A 137
 None
 1.27A 4a7tA-6bo6A:
undetectable
4a7tF-6bo6A:
undetectable		 4a7tA-6bo6A:
undetectable
4a7tF-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 6bo6 -
(-) 		5 / 12 PHE A 549
GLY A 506
PHE A 514
ARG A 480
LEU A 478
 None
 1.12A 4kotA-6bo6A:
undetectable		 4kotA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A206_1
(UNCHARACTERIZED
PROTEIN)		 6bo6 -
(-) 		5 / 10 PHE A 549
GLY A 506
PHE A 514
ARG A 480
LEU A 478
 None
 1.09A 4kouA-6bo6A:
undetectable		 4kouA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 6bo6 -
(-) 		5 / 12 PHE A 549
GLY A 506
PHE A 514
ARG A 480
LEU A 478
 None
 1.04A 4kowA-6bo6A:
undetectable		 4kowA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 6bo6 -
(-) 		3 / 3 ARG A 410
ASP A 363
ARG A 181
 None
 0.94A 4mx0A-6bo6A:
undetectable		 4mx0A-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 6bo6 -
(-) 		3 / 3 ALA A 131
TRP A  65
VAL A  66
 None
 0.40A 4w9nC-6bo6A:
undetectable		 4w9nC-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6bo6 -
(-) 		5 / 12 GLY A 358
ILE A 328
GLN A 559
PHE A 303
PHE A 301
 None
 1.23A 4zvmA-6bo6A:
undetectable
4zvmB-6bo6A:
undetectable		 4zvmA-6bo6A:
undetectable
4zvmB-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C8T_B_SAMB605_0
(GUANINE-N7
METHYLTRANSFERASE)		 6bo6 -
(-) 		5 / 11 PRO A 182
ALA A  89
PHE A 110
TYR A 346
ASN A 315
 None
 1.43A 5c8tB-6bo6A:
undetectable		 5c8tB-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 6bo6 -
(-) 		3 / 3 ASP A 465
LEU A 478
ARG A 480
 None
 0.50A 5e8qA-6bo6A:
undetectable		 5e8qA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 6bo6 -
(-) 		3 / 3 HIS A 309
GLU A 516
ASN A 424
 None
E0V  A 701 (-2.6A)
E0V  A 701 (-3.3A)
 1.01A 5wbvA-6bo6A:
undetectable		 5wbvA-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 6bo6 -
(-) 		3 / 3 HIS A 309
GLU A 516
ASN A 424
 None
E0V  A 701 (-2.6A)
E0V  A 701 (-3.3A)
 1.02A 5wbvB-6bo6A:
undetectable		 5wbvB-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 6bo6 -
(-) 		3 / 3 ARG A 340
ILE A 362
SER A 421
 None
 0.82A 5zw2A-6bo6A:
undetectable		 5zw2A-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 6bo6 -
(-) 		5 / 12 VAL A 132
VAL A  90
GLY A  17
PRO A 314
GLY A 316
 None
 1.15A 6brdC-6bo6A:
undetectable		 6brdC-6bo6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 6bo6 -
(-) 		3 / 3 TRP A 420
ILE A 362
ASP A 363
 None
 0.50A 6i0y7-6bo6A:
undetectable		 6i0y7-6bo6A:
undetectable