SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bo7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 6bo7 HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE
(Plasmodium
vivax) 		4 / 7 LEU A  50
PHE A 191
LEU A 173
PHE A  82
 None
 0.96A 3asnC-6bo7A:
undetectable
3asnJ-6bo7A:
undetectable		 3asnC-6bo7A:
undetectable
3asnJ-6bo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 6bo7 HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE
(Plasmodium
vivax) 		4 / 6 HIS A 104
ASN A  67
ARG A  66
GLU A 100
 None
 1.22A 3galB-6bo7A:
undetectable		 3galB-6bo7A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6bo7 HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE
(Plasmodium
vivax) 		4 / 7 LEU A  50
PHE A 191
LEU A 173
PHE A  82
 None
 0.96A 3x2qC-6bo7A:
undetectable
3x2qJ-6bo7A:
undetectable		 3x2qC-6bo7A:
undetectable
3x2qJ-6bo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 6bo7 HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE
(Plasmodium
vivax) 		5 / 12 GLY A  24
ILE A 193
VAL A 198
ILE A  17
ILE A  19
 None
None
YPG  A 303 (-4.3A)
None
None
 0.61A 5e5jA-6bo7A:
undetectable		 5e5jA-6bo7A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_1
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 6bo7 HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE
(Plasmodium
vivax) 		4 / 4 ASP A 204
GLY A  78
ASP A 145
ASP A 148
 MG  A 302 ( 2.5A)
YPG  A 303 (-3.8A)
MG  A 301 (-3.3A)
YPG  A 303 (-4.2A)
 1.18A 5e72A-6bo7A:
2.1		 5e72A-6bo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 6bo7 HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE
(Plasmodium
vivax) 		3 / 3 LYS A  -1
HIS A   1
HIS A  -1
 None
 1.39A 5oexB-6bo7A:
undetectable		 5oexB-6bo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 6bo7 HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE
(Plasmodium
vivax) 		3 / 3 LYS A  -1
HIS A   1
HIS A  -1
 None
 1.40A 5oexC-6bo7A:
undetectable		 5oexC-6bo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6bo7 HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE
(Plasmodium
vivax) 		4 / 5 LEU A  50
PHE A 191
LEU A 173
PHE A  82
 None
 0.99A 5x19C-6bo7A:
undetectable
5x19J-6bo7A:
undetectable		 5x19C-6bo7A:
undetectable
5x19J-6bo7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6bo7 HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE
(Plasmodium
vivax) 		4 / 7 LEU A  50
PHE A 191
LEU A 173
PHE A  82
 None
 0.96A 5x1fP-6bo7A:
undetectable
5x1fW-6bo7A:
undetectable		 5x1fP-6bo7A:
undetectable
5x1fW-6bo7A:
undetectable