SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 12 ILE A 725
PHE A 723
GLY A 727
LEU A 783
LEU A 754
None
1.30A 1fm6X-6bogA:
undetectable
1fm6X-6bogA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 8 GLU A 375
GLY A 374
LEU A 370
ASP A 381
None
0.81A 1jg4A-6bogA:
undetectable
1jg4A-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 7 PHE A  55
THR A  62
VAL A 107
ASP A  59
ILE A  61
None
1.23A 1p7rA-6bogA:
undetectable
1p7rA-6bogA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 12 SER A  11
PHE A  34
VAL A  30
PHE A   3
ALA A  44
None
1.23A 1q23A-6bogA:
undetectable
1q23B-6bogA:
undetectable
1q23A-6bogA:
15.45
1q23B-6bogA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 12 SER A  11
PHE A  34
VAL A  30
PHE A   3
ALA A  44
None
1.20A 1q23H-6bogA:
undetectable
1q23I-6bogA:
undetectable
1q23H-6bogA:
15.45
1q23I-6bogA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
6 / 10 LEU A 331
GLY A 308
ALA A 170
GLY A 166
ILE A 190
VAL A 416
None
1.20A 1t3rA-6bogA:
undetectable
1t3rA-6bogA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
3 / 3 ASN A 160
LEU A 702
HIS A 163
None
0.85A 2q6fB-6bogA:
undetectable
2q6fB-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 THR A 248
ALA A  44
ARG A 234
PRO A 245
None
1.32A 2ql8A-6bogA:
undetectable
2ql8B-6bogA:
undetectable
2ql8A-6bogA:
undetectable
2ql8B-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 ASP A 280
ILE A 205
LEU A 191
GLU A 218
None
0.90A 2ya7B-6bogA:
undetectable
2ya7B-6bogA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 ASP A 280
ILE A 205
LEU A 191
GLU A 218
None
0.95A 2ya7D-6bogA:
undetectable
2ya7D-6bogA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 12 ILE A 726
LEU A 722
ARG A 129
ILE A 784
PHE A 751
None
0.96A 2ygnA-6bogA:
undetectable
2ygnA-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
3 / 3 MET A 746
MET A  54
PHE A 751
None
0.97A 3gn8A-6bogA:
undetectable
3gn8A-6bogA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 12 ILE A  10
ASP A  12
THR A  51
VAL A  53
SER A 793
None
1.02A 3kpdB-6bogA:
undetectable
3kpdB-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 10 LEU A  81
LEU A  80
GLY A  79
THR A   4
VAL A  22
None
1.31A 3lxiA-6bogA:
undetectable
3lxiA-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 8 ASP A 121
ASP A 795
GLY A 794
PRO A 111
GLN A 112
None
1.31A 3s3mA-6bogA:
undetectable
3s3mA-6bogA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 8 ASP A 795
GLY A 794
PRO A 111
GLN A 112
None
1.01A 3s3nA-6bogA:
undetectable
3s3nA-6bogA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
3 / 3 ASN A 862
ALA A 127
ARG A 131
None
0.89A 3tj7C-6bogA:
undetectable
3tj7D-6bogA:
undetectable
3tj7C-6bogA:
undetectable
3tj7D-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 HIS A 692
GLU A 402
ASP A 381
ASP A 409
None
1.20A 4blvA-6bogA:
undetectable
4blvA-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 9 LEU A  81
LEU A  80
GLY A  79
THR A   4
VAL A  22
None
1.31A 4c9kA-6bogA:
undetectable
4c9kA-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 9 LEU A  81
LEU A  80
GLY A  79
THR A   4
VAL A  22
None
1.28A 4c9kB-6bogA:
undetectable
4c9kB-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 9 LEU A  81
LEU A  80
GLY A  79
THR A   4
VAL A  22
None
1.34A 4c9kB-6bogA:
undetectable
4c9kB-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 5 THR A 421
THR A 313
HIS A 324
LEU A 417
None
1.26A 4lvcA-6bogA:
undetectable
4lvcA-6bogA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 5 THR A 421
THR A 313
HIS A 324
LEU A 417
None
1.26A 4lvcC-6bogA:
undetectable
4lvcC-6bogA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
6 / 9 LEU A 331
GLY A 308
ALA A 170
GLY A 166
ILE A 190
VAL A 416
None
1.20A 4q1wA-6bogA:
undetectable
4q1wA-6bogA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 12 ALA A 200
GLY A 308
ILE A 161
ALA A 162
GLY A 166
None
0.96A 4r29D-6bogA:
undetectable
4r29D-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
3 / 3 ARG A  41
GLU A 201
TYR A  43
None
0.96A 4r29D-6bogA:
undetectable
4r29D-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A506_1
(HOMOSPERMIDINE
SYNTHASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 ARG A 920
ARG A 415
ASP A 164
ASP A 409
None
1.25A 4xqeA-6bogA:
2.7
4xqeA-6bogA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 ARG A 920
ARG A 415
ASP A 164
ASP A 409
None
1.26A 4xqeB-6bogA:
undetectable
4xqeB-6bogA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 SER A 153
ASP A 598
GLY A 180
GLU A 178
None
None
SO4  A1001 (-3.3A)
None
1.07A 5cdqA-6bogA:
4.2
5cdqC-6bogA:
4.2
5cdqD-6bogA:
undetectable
5cdqA-6bogA:
9.51
5cdqC-6bogA:
9.51
5cdqD-6bogA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWK_F_EVPF102_1
(DNA TOPOISOMERASE
2-ALPHA)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 5 GLY A 595
ASP A 598
ARG A 422
MET A 189
None
1.26A 5gwkA-6bogA:
3.7
5gwkA-6bogA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
6 / 9 LEU A 331
GLY A 308
ALA A 170
GLY A 166
ILE A 190
VAL A 416
None
1.19A 5kr0B-6bogA:
undetectable
5kr0B-6bogA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 11 LEU A 331
ALA A 170
GLY A 166
ILE A 190
VAL A 416
None
1.13A 5kr2B-6bogA:
undetectable
5kr2B-6bogA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_A_SAMA304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
5 / 12 LEU A 311
GLY A 308
ILE A 299
LEU A 330
ALA A 303
None
0.97A 5l0zA-6bogA:
undetectable
5l0zA-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 ARG A 599
LEU A 597
ARG A 593
ARG A 596
None
None
None
SO4  A1002 (-2.2A)
1.28A 5l6eA-6bogA:
undetectable
5l6eB-6bogA:
undetectable
5l6eA-6bogA:
undetectable
5l6eB-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
3 / 3 MET A 321
GLU A 690
ARG A 419
None
0.95A 5tjyA-6bogA:
2.7
5tjyA-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
3 / 3 MET A 321
GLU A 690
ARG A 419
None
0.98A 5tjzA-6bogA:
undetectable
5tjzA-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 8 GLY A 954
GLU A 896
ILE A 903
ASP A 951
None
0.79A 5vlmD-6bogA:
3.0
5vlmD-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 TRP A  67
SER A  63
HIS A  64
ARG A  98
None
1.17A 5x7pA-6bogA:
undetectable
5x7pA-6bogA:
4.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 TRP A  67
SER A  63
HIS A  64
ARG A  98
None
1.15A 5x7pB-6bogA:
undetectable
5x7pB-6bogA:
4.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 TRP A  67
SER A  63
HIS A  64
ARG A  98
None
1.12A 5x7qA-6bogA:
undetectable
5x7qA-6bogA:
4.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 TRP A  67
SER A  63
HIS A  64
ARG A  98
None
1.16A 5x7qB-6bogA:
undetectable
5x7qB-6bogA:
4.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 TRP A  67
SER A  63
HIS A  64
ARG A  98
None
1.10A 5x7rA-6bogA:
undetectable
5x7rA-6bogA:
4.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 TRP A  67
SER A  63
HIS A  64
ARG A  98
None
1.11A 5x7rB-6bogA:
undetectable
5x7rB-6bogA:
4.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 6 LEU A 888
GLN A 112
LEU A 115
LEU A 960
None
1.06A 5yvnA-6bogA:
undetectable
5yvnA-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
3 / 3 GLY A  94
THR A  86
GLU A  72
None
0.52A 6b58A-6bogA:
4.7
6b58A-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
3 / 3 ARG A 961
ARG A 131
ARG A 842
None
1.05A 6bplA-6bogA:
4.7
6bplB-6bogA:
5.1
6bplA-6bogA:
23.40
6bplB-6bogA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 7 ASP A 789
PHE A 108
SER A 793
GLY A 794
None
0.96A 6ekzA-6bogA:
undetectable
6ekzA-6bogA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 4 LEU A 438
ASP A 488
PRO A 489
ARG A 490
None
0.95A 6fgdA-6bogA:
undetectable
6fgdA-6bogA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 5 THR A 421
THR A 313
HIS A 324
LEU A 417
None
1.32A 6gbnA-6bogA:
undetectable
6gbnA-6bogA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)
6bog RNA
POLYMERASE-ASSOCIATE
D PROTEIN RAPA

(Escherichia
coli)
4 / 5 THR A 421
THR A 313
HIS A 324
LEU A 417
None
1.33A 6gbnD-6bogA:
undetectable
6gbnD-6bogA:
11.48