SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bpc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 8 LYS A 437
LEU A 440
PHE A 388
LEU A 392
 None
 0.59A 1v54C-6bpcA:
6.9
1v54J-6bpcA:
undetectable		 1v54C-6bpcA:
undetectable
1v54J-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 8 LYS A 437
LEU A 440
PHE A 388
LEU A 392
 None
 0.65A 1v54P-6bpcA:
6.9
1v54W-6bpcA:
undetectable		 1v54P-6bpcA:
undetectable
1v54W-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 8 LYS A 437
LEU A 440
PHE A 388
LEU A 392
 None
 0.59A 2dyrC-6bpcA:
6.9
2dyrJ-6bpcA:
undetectable		 2dyrC-6bpcA:
undetectable
2dyrJ-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 8 LYS A 437
LEU A 440
PHE A 388
LEU A 392
 None
 0.67A 2dyrP-6bpcA:
6.9
2dyrW-6bpcA:
undetectable		 2dyrP-6bpcA:
undetectable
2dyrW-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 8 LYS A 437
LEU A 440
PHE A 388
LEU A 392
 None
 0.72A 2eikP-6bpcA:
6.8
2eikW-6bpcA:
undetectable		 2eikP-6bpcA:
undetectable
2eikW-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 8 LYS A 437
LEU A 440
PHE A 388
LEU A 392
 None
 0.59A 2eilC-6bpcA:
6.9
2eilJ-6bpcA:
undetectable		 2eilC-6bpcA:
undetectable
2eilJ-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 7 LYS A 437
LEU A 440
PHE A 388
LEU A 392
 None
 0.65A 2eimP-6bpcA:
6.9
2eimW-6bpcA:
undetectable		 2eimP-6bpcA:
undetectable
2eimW-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 6 LEU A 307
LEU A 419
ILE A 303
ARG A 304
 None
 1.15A 2rlfB-6bpcA:
undetectable
2rlfC-6bpcA:
undetectable		 2rlfB-6bpcA:
17.74
2rlfC-6bpcA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 7 LYS A 437
LEU A 440
PHE A 388
LEU A 392
 None
 0.67A 3asnP-6bpcA:
6.9
3asnW-6bpcA:
undetectable		 3asnP-6bpcA:
undetectable
3asnW-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 7 LYS A 437
LEU A 440
PHE A 388
LEU A 392
 None
 0.72A 3asoP-6bpcA:
6.9
3asoW-6bpcA:
undetectable		 3asoP-6bpcA:
undetectable
3asoW-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 6bpc MONOCLONAL ANTIBODY
4F7 FAB LIGHT CHAIN
(Mus
musculus) 		4 / 8 ILE C  26
ALA C  49
PHE C  95
ASN C  52
 None
 0.94A 3hrdA-6bpcC:
undetectable
3hrdB-6bpcC:
undetectable		 3hrdA-6bpcC:
12.09
3hrdB-6bpcC:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 6bpc MONOCLONAL ANTIBODY
4F7 FAB LIGHT CHAIN
(Mus
musculus) 		5 / 12 ASP C  41
VAL C  39
VAL C 102
SER C 194
SER C 104
 None
 1.33A 3nyaA-6bpcC:
undetectable		 3nyaA-6bpcC:
9.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_B_ADNB1_1
(UNCHARACTERIZED
PROTEIN)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		5 / 9 ILE A 453
PRO A 257
LEU A 457
THR A 377
GLU A 380
 None
 1.24A 3oi8A-6bpcA:
undetectable
3oi8B-6bpcA:
undetectable		 3oi8A-6bpcA:
15.92
3oi8B-6bpcA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		3 / 3 HIS A 397
SER A 431
ASN A 425
 None
 0.79A 3s8pB-6bpcA:
undetectable		 3s8pB-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 7 GLU A 255
ILE A 251
GLU A 380
TYR A 177
 None
 0.63A 4a97A-6bpcA:
4.0		 4a97A-6bpcA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 7 GLU A 255
ILE A 251
GLU A 380
TYR A 177
 None
 0.65A 4a97D-6bpcA:
4.0		 4a97D-6bpcA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 7 GLU A 255
ILE A 251
GLU A 380
TYR A 177
 None
 0.64A 4a97H-6bpcA:
1.5		 4a97H-6bpcA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 6bpc MONOCLONAL ANTIBODY
4F7 FAB LIGHT CHAIN
(Mus
musculus) 		5 / 12 ASP C  41
VAL C  39
VAL C 102
SER C 194
SER C 104
 None
 1.36A 4amjA-6bpcC:
undetectable		 4amjA-6bpcC:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 6 PHE A 202
ILE A 221
PHE A 205
PHE A 201
 None
 1.05A 4fgkA-6bpcA:
undetectable		 4fgkA-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 4 ILE A 237
SER A 234
ASP A 176
ASP A 173
 None
 1.08A 4krhB-6bpcA:
undetectable		 4krhB-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		5 / 12 SER A 431
GLU A 204
ARG A 207
ILE A 426
ILE A 325
 None
 1.36A 4uroB-6bpcA:
undetectable		 4uroB-6bpcA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 7 TYR A 186
TYR A 187
LEU A 188
PHE A 435
 None
 1.24A 4yv5A-6bpcA:
undetectable		 4yv5A-6bpcA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 7 TYR A 186
TYR A 187
LEU A 188
PHE A 435
 None
 1.23A 4yv5B-6bpcA:
undetectable		 4yv5B-6bpcA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		3 / 3 HIS A 397
SER A 431
ASN A 425
 None
 0.81A 5cprB-6bpcA:
undetectable		 5cprB-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 6 HIS A 222
GLU A 219
LEU A 307
TYR A 211
 None
 1.07A 5igiA-6bpcA:
undetectable		 5igiA-6bpcA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		5 / 12 TYR A 347
LEU A 440
ARG A 387
TYR A 177
ILE A 384
 None
 1.30A 5ljcA-6bpcA:
undetectable		 5ljcA-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 6 LYS A 437
LEU A 440
PHE A 388
LEU A 392
 None
 0.60A 5x19P-6bpcA:
6.8		 5x19P-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		4 / 7 LYS A 437
LEU A 440
PHE A 388
LEU A 392
 None
 0.63A 5x1fP-6bpcA:
6.8
5x1fW-6bpcA:
undetectable		 5x1fP-6bpcA:
undetectable
5x1fW-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		5 / 12 LEU A 405
PHE A 322
ILE A 426
ILE A 215
LEU A 307
 None
 1.21A 5y2tB-6bpcA:
undetectable		 5y2tB-6bpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 6bpc RETICULOCYTE BINDING
PROTEIN 2, PUTATIVE
(Plasmodium
vivax) 		5 / 12 ILE A 296
ASN A 428
ASN A 300
ILE A 189
LYS A 394
 None
 1.39A 6dwnB-6bpcA:
undetectable		 6dwnB-6bpcA:
17.44