SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bpd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)		 6bpd MONOCLONAL ANTIBODY
10B12 FAB HEAVY
CHAIN
(Mus
musculus) 		4 / 4 THR A 142
PRO A 172
THR A 141
PRO A 143
 None
 1.32A 1dsdC-6bpdA:
undetectable		 1dsdC-6bpdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)		 6bpd MONOCLONAL ANTIBODY
10B12 FAB HEAVY
CHAIN
(Mus
musculus) 		4 / 4 THR A 142
PRO A 172
THR A 141
PRO A 143
 None
 1.32A 1dsdC-6bpdA:
undetectable		 1dsdC-6bpdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 6bpd MONOCLONAL ANTIBODY
10B12 FAB HEAVY
CHAIN
(Mus
musculus) 		4 / 7 ALA A  43
TYR A  46
SER A  73
ALA A  91
 None
 1.02A 1k5qA-6bpdA:
undetectable
1k5qB-6bpdA:
undetectable		 1k5qA-6bpdA:
undetectable
1k5qB-6bpdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 6bpd MONOCLONAL ANTIBODY
10B12 FAB HEAVY
CHAIN
(Mus
musculus) 		5 / 11 VAL A 136
ALA A  31
SER A 103
SER A  36
GLY A  34
 None
 1.32A 4mmaA-6bpdA:
undetectable		 4mmaA-6bpdA:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA607_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 6bpd MONOCLONAL ANTIBODY
10B12 FAB HEAVY
CHAIN
(Mus
musculus) 		4 / 4 GLY A  68
ARG A  84
ASN A  78
LEU A  89
 None
 1.17A 6b58A-6bpdA:
undetectable		 6b58A-6bpdA:
undetectable