SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bq8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 6bq8 CGMP-DEPENDENT
PROTEIN KINASE 2
(Homo
sapiens) 		3 / 3 ASP A 308
LYS A 309
ASP A 311
 None
 0.85A 4a7tA-6bq8A:
undetectable		 4a7tA-6bq8A:
16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 6bq8 CGMP-DEPENDENT
PROTEIN KINASE 2
(Homo
sapiens) 		5 / 12 ILE A 314
ALA A 368
PHE A 355
LEU A 326
ILE A 313
 6FW  A 501 ( 3.9A)
6FW  A 501 (-3.1A)
None
None
None
 1.07A 4kjkA-6bq8A:
undetectable		 4kjkA-6bq8A:
undetectable