SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bqy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 6bqy TYROSINE--TRNA
LIGASE
(Acinetobacter
baumannii) 		6 / 11 GLY A  48
HIS A  57
HIS A  60
GLY A 197
ASP A 199
GLN A 200
 EDO  A 501 (-3.6A)
None
None
None
None
None
 0.93A 1jzsA-6bqyA:
2.1		 1jzsA-6bqyA:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 6bqy TYROSINE--TRNA
LIGASE
(Acinetobacter
baumannii) 		5 / 12 HIS A  57
HIS A  60
GLY A 197
ASP A 199
GLN A 200
 None
 1.04A 1qu2A-6bqyA:
5.3		 1qu2A-6bqyA:
6.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 6bqy TYROSINE--TRNA
LIGASE
(Acinetobacter
baumannii) 		5 / 9 GLU A 133
ASN A 131
ILE A  81
ALA A 110
PHE A  49
 None
EDO  A 502 (-3.4A)
None
None
None
 1.37A 2drdA-6bqyA:
undetectable		 2drdA-6bqyA:
6.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 6bqy TYROSINE--TRNA
LIGASE
(Acinetobacter
baumannii) 		4 / 6 GLN A 200
HIS A  57
HIS A  60
ASP A 199
 None
 1.14A 3nvcA-6bqyA:
undetectable		 3nvcA-6bqyA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 6bqy TYROSINE--TRNA
LIGASE
(Acinetobacter
baumannii) 		4 / 8 GLN A 200
ASP A 159
LEU A 204
ASN A 203
 None
 0.88A 5hwaA-6bqyA:
undetectable		 5hwaA-6bqyA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW3_A_ACTA404_0
(FERREDOXIN--NADP
REDUCTASE)		 6bqy TYROSINE--TRNA
LIGASE
(Acinetobacter
baumannii) 		4 / 4 GLN A 200
LEU A 204
ASN A 203
GLN A 182
 None
None
None
EDO  A 501 (-3.4A)
 1.44A 5vw3A-6bqyA:
2.6		 5vw3A-6bqyA:
undetectable