SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6br8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 6br8 PROTEIN A6 HOMOLOG
(Fowlpox
virus) 		4 / 7 ILE A 143
ILE A 140
LYS A 139
THR A 170
 6OU  A 405 (-4.4A)
6OU  A 405 ( 4.5A)
None
6OU  A 405 (-4.3A)
 0.86A 1sbrB-6br8A:
undetectable		 1sbrB-6br8A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 6br8 PROTEIN A6 HOMOLOG
(Fowlpox
virus) 		5 / 9 VAL A 341
THR A 345
VAL A 357
ASP A 358
ILE A 362
 6OU  A 401 ( 4.3A)
6OU  A 401 (-4.7A)
6OU  A 401 ( 4.9A)
None
PGV  A 404 ( 4.1A)
 1.46A 2l8mA-6br8A:
undetectable		 2l8mA-6br8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 6br8 PROTEIN A6 HOMOLOG
(Fowlpox
virus) 		3 / 3 GLU A 368
TYR A 330
GLU A 331
 None
PGV  A 404 (-3.6A)
PGV  A 404 (-4.2A)
 0.70A 4ryaA-6br8A:
undetectable		 4ryaA-6br8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6br8 PROTEIN A6 HOMOLOG
(Fowlpox
virus) 		4 / 7 SER A 316
THR A 190
VAL A 193
ILE A 133
 None
 1.19A 5vkqA-6br8A:
undetectable
5vkqB-6br8A:
undetectable		 5vkqA-6br8A:
undetectable
5vkqB-6br8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6br8 PROTEIN A6 HOMOLOG
(Fowlpox
virus) 		4 / 8 SER A 316
THR A 190
VAL A 193
ILE A 133
 None
 1.17A 5vkqB-6br8A:
undetectable
5vkqC-6br8A:
undetectable		 5vkqB-6br8A:
undetectable
5vkqC-6br8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 6br8 PROTEIN A6 HOMOLOG
(Fowlpox
virus) 		4 / 7 SER A 316
THR A 190
VAL A 193
ILE A 133
 None
 1.17A 5vkqC-6br8A:
undetectable
5vkqD-6br8A:
undetectable		 5vkqC-6br8A:
undetectable
5vkqD-6br8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 6br8 PROTEIN A6 HOMOLOG
(Fowlpox
virus) 		3 / 3 ILE A 269
ASN A 261
CYH A 221
 None
 0.69A 6bp4A-6br8A:
undetectable		 6bp4A-6br8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 6br8 PROTEIN A6 HOMOLOG
(Fowlpox
virus) 		4 / 5 SER A 237
VAL A 236
LYS A 234
ASN A 233
 None
None
None
6OU  A 405 (-3.7A)
 1.46A 6fi4A-6br8A:
undetectable
6fi4B-6br8A:
undetectable		 6fi4A-6br8A:
undetectable
6fi4B-6br8A:
undetectable