SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6brs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 7 LEU A 582
LEU A 568
GLY A 628
LEU A 623
 HG  A1006 (-4.6A)
None
None
None
 0.74A 1gtiB-6brsA:
undetectable		 1gtiB-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		3 / 3 ASP A 452
LEU A 261
LEU A 262
 None
 0.77A 1ikeA-6brsA:
undetectable		 1ikeA-6brsA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		3 / 3 ASP A 452
LEU A 261
LEU A 262
 None
 0.78A 1np1B-6brsA:
undetectable		 1np1B-6brsA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 826
LEU A 829
ALA A 833
GLU A 836
ILE A 794
 None
 0.62A 1s9pA-6brsA:
undetectable		 1s9pA-6brsA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		5 / 12 LEU A 826
LEU A 829
ALA A 833
GLU A 836
ILE A 794
 None
 0.88A 1s9pC-6brsA:
undetectable		 1s9pC-6brsA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 LEU A 141
ARG A  88
THR A  99
LEU A 101
 None
 1.04A 1v54A-6brsA:
undetectable
1v54J-6brsA:
undetectable		 1v54A-6brsA:
undetectable
1v54J-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		5 / 12 ALA A 114
HIS A  84
GLU A  83
HIS A  80
GLU A 165
 None
None
HG  A1004 ( 4.5A)
HG  A1004 (-3.4A)
HG  A1004 (-2.8A)
 0.78A 2c6nA-6brsA:
undetectable		 2c6nA-6brsA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 LEU A 141
ARG A  88
THR A  99
LEU A 101
 None
 1.05A 2dyrA-6brsA:
undetectable
2dyrJ-6brsA:
undetectable		 2dyrA-6brsA:
undetectable
2dyrJ-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 LEU A 141
ARG A  88
THR A  99
LEU A 101
 None
 1.01A 2dysA-6brsA:
undetectable
2dysJ-6brsA:
undetectable		 2dysA-6brsA:
undetectable
2dysJ-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 LEU A 141
ARG A  88
THR A  99
LEU A 101
 None
 1.08A 2eijA-6brsA:
undetectable
2eijJ-6brsA:
undetectable		 2eijA-6brsA:
undetectable
2eijJ-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 LEU A 141
ARG A  88
THR A  99
LEU A 101
 None
 1.04A 2eilA-6brsA:
undetectable
2eilJ-6brsA:
undetectable		 2eilA-6brsA:
undetectable
2eilJ-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		5 / 12 PHE A 834
LEU A 783
ILE A 778
ALA A 779
VAL A 814
 None
 1.17A 2g78A-6brsA:
undetectable		 2g78A-6brsA:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 5 LEU A 602
VAL A 519
LEU A 533
ARG A 882
 None
 1.08A 2oiqA-6brsA:
undetectable		 2oiqA-6brsA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 7 ALA A 136
THR A 137
ALA A 140
PRO A 128
 None
 0.72A 2ql8A-6brsA:
4.2
2ql8B-6brsA:
4.2		 2ql8A-6brsA:
undetectable
2ql8B-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 LEU A 141
ARG A  88
THR A  99
LEU A 101
 None
 1.01A 2zxwA-6brsA:
undetectable
2zxwJ-6brsA:
undetectable		 2zxwA-6brsA:
undetectable
2zxwJ-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 LEU A 141
ARG A  88
THR A  99
LEU A 101
 None
 1.04A 3abmA-6brsA:
undetectable
3abmJ-6brsA:
undetectable		 3abmA-6brsA:
undetectable
3abmJ-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 LEU A 141
ARG A  88
THR A  99
LEU A 101
 None
 1.02A 3asnA-6brsA:
undetectable
3asnJ-6brsA:
undetectable		 3asnA-6brsA:
undetectable
3asnJ-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 LEU A 141
ARG A  88
THR A  99
LEU A 101
 None
 1.04A 3asoA-6brsA:
undetectable
3asoJ-6brsA:
undetectable		 3asoA-6brsA:
undetectable
3asoJ-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		3 / 3 ARG A 120
ASP A  70
ASP A  65
 None
 0.88A 3jb3A-6brsA:
undetectable		 3jb3A-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_2
(GENOME POLYPROTEIN)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 4 GLN A 517
PHE A 514
TYR A 878
LEU A 702
 None
 1.49A 3keeC-6brsA:
undetectable		 3keeC-6brsA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_2
(POL POLYPROTEIN)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		5 / 9 ALA A 236
ASP A 235
GLY A 229
ILE A 228
PRO A 127
 None
 1.27A 3u7sB-6brsA:
undetectable		 3u7sB-6brsA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 5 ALA A 341
MET A 308
THR A 304
PHE A 287
 None
 1.29A 3vasB-6brsA:
undetectable		 3vasB-6brsA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_A_VK3A202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 5 ARG A 724
TYR A 700
TYR A 620
LEU A 544
 None
 1.33A 4f8yA-6brsA:
undetectable
4f8yB-6brsA:
undetectable		 4f8yA-6brsA:
18.48
4f8yB-6brsA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		5 / 10 ALA A 546
ILE A 703
ALA A 704
ALA A 608
THR A 607
 None
 1.04A 4j14A-6brsA:
undetectable		 4j14A-6brsA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		3 / 4 SER A 296
GLY A 425
GLU A 397
 None
 0.62A 4juoA-6brsA:
1.3
4juoC-6brsA:
2.2		 4juoA-6brsA:
10.47
4juoC-6brsA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		6 / 11 LEU A 138
ALA A 236
GLY A 229
ILE A 228
PRO A 127
THR A 137
 None
 1.39A 4njtA-6brsA:
undetectable		 4njtA-6brsA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		6 / 11 LEU A 138
ALA A 236
GLY A 229
ILE A 228
PRO A 127
THR A 137
 None
 1.38A 4rvjA-6brsA:
undetectable		 4rvjA-6brsA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		6 / 11 LEU A 138
ALA A 236
GLY A 229
ILE A 228
PRO A 127
THR A 137
 None
 1.38A 4rvjC-6brsA:
undetectable		 4rvjC-6brsA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 ARG A 869
ILE A 872
GLN A 868
ASP A 863
 None
 1.10A 4w5qA-6brsA:
undetectable		 4w5qA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 ARG A 869
ILE A 872
GLN A 868
ASP A 863
 None
 1.07A 4w5tA-6brsA:
undetectable		 4w5tA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 ARG A 869
ILE A 872
GLN A 868
ASP A 863
 None
 1.18A 4z4cA-6brsA:
undetectable		 4z4cA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 TYR A 700
GLY A 506
SER A 525
LEU A 524
 None
 1.28A 5bphA-6brsA:
undetectable		 5bphA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 4 TYR A 700
GLY A 506
SER A 525
LEU A 524
 None
 1.25A 5bphC-6brsA:
undetectable		 5bphC-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		5 / 12 TYR A 257
LEU A 262
GLY A 337
ILE A 336
GLY A  67
 None
None
PO4  A1002 (-3.2A)
None
None
 1.03A 5d4uC-6brsA:
undetectable		 5d4uC-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		3 / 3 TRP A 412
ARG A  61
LEU A 141
 None
 0.88A 5dbyA-6brsA:
undetectable		 5dbyA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 8 TYR A 907
TRP A 827
THR A 828
LEU A 914
 None
 1.46A 5kxiA-6brsA:
undetectable
5kxiB-6brsA:
undetectable		 5kxiA-6brsA:
10.96
5kxiB-6brsA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 8 TYR A 907
TRP A 827
THR A 828
LEU A 914
 None
 1.45A 5kxiD-6brsA:
undetectable
5kxiE-6brsA:
undetectable		 5kxiD-6brsA:
10.96
5kxiE-6brsA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		5 / 12 ILE A 231
GLY A 229
VAL A 405
ILE A 240
ALA A 236
 None
 1.13A 5n0xA-6brsA:
undetectable		 5n0xA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 4 VAL A  86
VAL A  82
TYR A 214
GLN A 211
 None
 1.35A 5qggA-6brsA:
undetectable		 5qggA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 4 VAL A  86
VAL A  82
TYR A 214
GLN A 211
 None
 1.35A 5qgoA-6brsA:
undetectable		 5qgoA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 4 VAL A  86
VAL A  82
TYR A 214
GLN A 211
 None
 1.35A 5qgpA-6brsA:
undetectable		 5qgpA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 4 VAL A  86
VAL A  82
TYR A 214
GLN A 211
 None
 1.36A 5qgqA-6brsA:
undetectable		 5qgqA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 4 VAL A  86
VAL A  82
TYR A 214
GLN A 211
 None
 1.34A 5qhbA-6brsA:
undetectable		 5qhbA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_1
(REGULATORY PROTEIN
TETR)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 7 GLN A 861
GLY A 859
ILE A 854
GLN A 849
 None
 1.11A 5vlmC-6brsA:
undetectable		 5vlmC-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 LEU A 141
ARG A  88
THR A  99
LEU A 101
 None
 1.08A 5x1fA-6brsA:
undetectable
5x1fJ-6brsA:
undetectable		 5x1fA-6brsA:
undetectable
5x1fJ-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		3 / 3 ARG A 870
PHE A 853
ARG A 860
 None
 1.19A 5y9yA-6brsA:
undetectable		 5y9yA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 5 ASN A 348
VAL A 284
LEU A 454
SER A 458
 PO4  A1003 (-2.8A)
None
None
None
 1.30A 6a7pA-6brsA:
undetectable		 6a7pA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		4 / 6 ARG A 869
ILE A 872
GLN A 868
ASP A 863
 None
 1.17A 6cbdA-6brsA:
undetectable		 6cbdA-6brsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 6brs PUTATIVE ZINC
PROTEASE
(Pectobacterium
atrosepticum) 		3 / 3 ARG A  88
HIS A  84
ARG A 108
 None
 1.02A 6dwdD-6brsA:
undetectable		 6dwdD-6brsA:
undetectable