SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bs9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 6bs9 STAGE III
SPORULATION PROTEIN
AB
(Bacillus
subtilis) 		4 / 5 VAL A  97
GLN A  34
PHE A  75
ARG A  30
 None
 1.27A 3bjwH-6bs9A:
1.6		 3bjwH-6bs9A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 6bs9 STAGE III
SPORULATION PROTEIN
AB
(Bacillus
subtilis) 		4 / 6 VAL A  97
GLN A  34
PHE A  75
ARG A  30
 None
 1.22A 3bjwF-6bs9A:
1.6		 3bjwF-6bs9A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 6bs9 STAGE III
SPORULATION PROTEIN
AB
(Bacillus
subtilis) 		5 / 12 HIS A 136
SER A 140
GLU A 141
ILE A  32
LEU A  39
 SO4  A 202 (-4.4A)
None
None
None
None
 1.13A 4foxA-6bs9A:
undetectable		 4foxA-6bs9A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_B_SAMB501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 6bs9 STAGE III
SPORULATION PROTEIN
AB
(Bacillus
subtilis) 		5 / 12 LEU A  64
ILE A  60
ASP A  77
LEU A 101
LEU A  71
 None
 1.15A 5nfjB-6bs9A:
undetectable		 5nfjB-6bs9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 6bs9 STAGE III
SPORULATION PROTEIN
AB
(Bacillus
subtilis) 		5 / 12 LEU A  64
ILE A  60
ASP A  77
LEU A 101
LEU A  71
 None
 1.12A 5nfjC-6bs9A:
undetectable		 5nfjC-6bs9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA608_0
(ALPHA-AMYLASE)		 6bs9 STAGE III
SPORULATION PROTEIN
AB
(Bacillus
subtilis) 		4 / 6 PHE A 114
GLY A 115
THR A 117
GLN A 126
 None
 1.20A 6ag0A-6bs9A:
undetectable		 6ag0A-6bs9A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC606_0
(ALPHA-AMYLASE)		 6bs9 STAGE III
SPORULATION PROTEIN
AB
(Bacillus
subtilis) 		4 / 6 PHE A 114
GLY A 115
THR A 117
GLN A 126
 None
 1.22A 6ag0C-6bs9A:
undetectable		 6ag0C-6bs9A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 6bs9 STAGE III
SPORULATION PROTEIN
AB
(Bacillus
subtilis) 		4 / 6 ALA A  61
SER A  69
ALA A  74
SER A  73
 None
 0.98A 6bocA-6bs9A:
undetectable
6bocB-6bs9A:
undetectable
6bocC-6bs9A:
undetectable
6bocD-6bs9A:
undetectable		 6bocA-6bs9A:
undetectable
6bocB-6bs9A:
undetectable
6bocC-6bs9A:
undetectable
6bocD-6bs9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 6bs9 STAGE III
SPORULATION PROTEIN
AB
(Bacillus
subtilis) 		5 / 11 SER A  57
LEU A  71
PHE A 114
ALA A  38
PHE A  72
 None
 1.47A 6qgbE-6bs9A:
undetectable		 6qgbE-6bs9A:
undetectable