SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bsu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)		 6bsu XYLOGLUCAN
6-XYLOSYLTRANSFERASE
1
(Arabidopsis
thaliana) 		5 / 11 ILE A 265
LEU A 267
GLY A 253
TYR A 259
VAL A 323
 None
 1.40A 1axwB-6bsuA:
undetectable		 1axwB-6bsuA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE201_1
(PROTEIN S100-A4)		 6bsu XYLOGLUCAN
6-XYLOSYLTRANSFERASE
1
(Arabidopsis
thaliana) 		4 / 7 PHE A 450
GLY A 186
MET A 235
PHE A 237
 None
 1.06A 3ko0D-6bsuA:
undetectable
3ko0E-6bsuA:
undetectable		 3ko0D-6bsuA:
19.80
3ko0E-6bsuA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6bsu XYLOGLUCAN
6-XYLOSYLTRANSFERASE
1
(Arabidopsis
thaliana) 		3 / 3 GLY A 342
SER A 341
TRP A 254
 None
 0.86A 4e7cD-6bsuA:
undetectable		 4e7cD-6bsuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 6bsu XYLOGLUCAN
6-XYLOSYLTRANSFERASE
1
(Arabidopsis
thaliana) 		3 / 3 SER A 157
TYR A 191
ASP A 168
 None
 0.82A 4rp8C-6bsuA:
undetectable		 4rp8C-6bsuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 6bsu XYLOGLUCAN
6-XYLOSYLTRANSFERASE
1
(Arabidopsis
thaliana) 		4 / 6 LYS A 293
GLY A 291
TYR A 117
ALA A 288
 None
 0.94A 4yshB-6bsuA:
undetectable		 4yshB-6bsuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 6bsu XYLOGLUCAN
6-XYLOSYLTRANSFERASE
1
(Arabidopsis
thaliana) 		4 / 6 THR A 417
ASN A 408
ILE A 360
GLU A 357
 None
 1.08A 5uigA-6bsuA:
undetectable		 5uigA-6bsuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H0F_B_Y70B502_0
(IKAROS (IKZF1)
PROTEIN CEREBLON)		 6bsu XYLOGLUCAN
6-XYLOSYLTRANSFERASE
1
(Arabidopsis
thaliana) 		5 / 12 ASN A 408
HIS A 418
TRP A 372
ASN A 404
GLY A 406
 None
 1.16A 6h0fB-6bsuA:
0.0
6h0fC-6bsuA:
0.0		 6h0fB-6bsuA:
22.47
6h0fC-6bsuA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H0F_E_Y70E502_0
(IKAROS (IKZF1)
PROTEIN CEREBLON)		 6bsu XYLOGLUCAN
6-XYLOSYLTRANSFERASE
1
(Arabidopsis
thaliana) 		5 / 12 ASN A 408
HIS A 418
TRP A 372
ASN A 404
GLY A 406
 None
 1.18A 6h0fE-6bsuA:
0.0
6h0fF-6bsuA:
0.0		 6h0fE-6bsuA:
22.47
6h0fF-6bsuA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H0F_H_Y70H502_0
(IKAROS (IKZF1)
PROTEIN CEREBLON)		 6bsu XYLOGLUCAN
6-XYLOSYLTRANSFERASE
1
(Arabidopsis
thaliana) 		5 / 12 ASN A 408
HIS A 418
TRP A 372
ASN A 404
GLY A 406
 None
 1.18A 6h0fH-6bsuA:
0.9
6h0fI-6bsuA:
undetectable		 6h0fH-6bsuA:
22.47
6h0fI-6bsuA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H0F_K_Y70K502_0
(IKAROS (IKZF1)
PROTEIN CEREBLON)		 6bsu XYLOGLUCAN
6-XYLOSYLTRANSFERASE
1
(Arabidopsis
thaliana) 		5 / 12 ASN A 408
HIS A 418
TRP A 372
ASN A 404
GLY A 406
 None
 1.17A 6h0fK-6bsuA:
0.0
6h0fL-6bsuA:
0.0		 6h0fK-6bsuA:
22.47
6h0fL-6bsuA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 6bsu XYLOGLUCAN
6-XYLOSYLTRANSFERASE
1
(Arabidopsis
thaliana) 		4 / 8 TYR A 170
VAL A 166
ASN A 164
PRO A 383
 None
 1.02A 6hzpA-6bsuA:
undetectable		 6hzpA-6bsuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_D_FFOD403_0
(THYMIDYLATE SYNTHASE)		 6bsu XYLOGLUCAN
6-XYLOSYLTRANSFERASE
1
(Arabidopsis
thaliana) 		5 / 10 PHE A 378
ASP A 168
LEU A 171
GLY A 167
ASN A 164
 None
 1.49A 6r2eD-6bsuA:
undetectable		 6r2eD-6bsuA:
undetectable