SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bsz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DLS_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 12 ILE A 151
SER A  39
ILE A  40
ASN A 356
LEU A  80
 None
SO4  A 603 (-2.6A)
None
None
None
 1.10A 1dlsA-6bszA:
undetectable		 1dlsA-6bszA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 11 TYR A 344
ASP A  84
ARG A 355
VAL A 402
ILE A 406
 None
 1.22A 1yatA-6bszA:
undetectable		 1yatA-6bszA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 12 ASN A 164
LEU A 166
ALA A 163
GLN A 173
LEU A  51
 None
 1.11A 2aa5A-6bszA:
undetectable		 2aa5A-6bszA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 12 LEU A 166
ALA A 163
GLN A 173
SER A 159
LEU A  51
 None
 1.37A 2aa5A-6bszA:
undetectable		 2aa5A-6bszA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 12 ASN A 164
LEU A 166
ALA A 163
GLN A 173
LEU A  51
 None
 1.10A 2aa5B-6bszA:
undetectable		 2aa5B-6bszA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 12 LEU A 166
ALA A 163
GLN A 173
SER A 159
LEU A  51
 None
 1.35A 2aa5B-6bszA:
undetectable		 2aa5B-6bszA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 12 ASN A 164
LEU A 166
ALA A 163
GLN A 173
LEU A  51
 None
 1.14A 2aa6A-6bszA:
undetectable		 2aa6A-6bszA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 12 ASN A 164
LEU A 166
ALA A 163
GLN A 173
LEU A  51
 None
 1.13A 2aa6B-6bszA:
undetectable		 2aa6B-6bszA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 11 TYR A 344
ASP A  84
ARG A 355
VAL A 402
ILE A 406
 None
 1.27A 2fkeA-6bszA:
undetectable		 2fkeA-6bszA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 11 LEU A 166
GLY A 152
ALA A 153
ILE A 102
VAL A 162
 None
 1.14A 2fxdA-6bszA:
undetectable		 2fxdA-6bszA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_A_SAMA801_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 10 GLY A 444
LEU A 443
SER A 411
HIS A 417
TYR A 414
 None
 1.40A 2h21A-6bszA:
undetectable		 2h21A-6bszA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_B_SAMB802_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 11 GLY A 444
LEU A 443
SER A 411
HIS A 417
TYR A 414
 None
 1.44A 2h21B-6bszA:
undetectable		 2h21B-6bszA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_C_SAMC803_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 11 GLY A 444
LEU A 443
SER A 411
HIS A 417
TYR A 414
 None
 1.45A 2h21C-6bszA:
undetectable		 2h21C-6bszA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		3 / 3 ALA A 360
VAL A 357
TRP A 358
 None
 0.94A 2izqA-6bszA:
undetectable
2izqB-6bszA:
undetectable		 2izqA-6bszA:
undetectable
2izqB-6bszA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		4 / 5 SER A 175
PHE A 192
VAL A 162
TYR A 176
 None
 1.36A 2x7hA-6bszA:
0.6		 2x7hA-6bszA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1372_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		4 / 5 SER A 175
PHE A 192
VAL A 162
TYR A 176
 None
 1.34A 2x7hB-6bszA:
undetectable		 2x7hB-6bszA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		3 / 3 THR A 179
SER A 310
LYS A 314
 GGL  A 601 (-3.2A)
None
GGL  A 601 (-3.0A)
 1.17A 3aocC-6bszA:
undetectable		 3aocC-6bszA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		4 / 5 ILE A 209
MET A 502
ILE A 488
HIS A 490
 None
 1.24A 3eteB-6bszA:
5.2
3eteC-6bszA:
4.3		 3eteB-6bszA:
12.39
3eteC-6bszA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 10 TYR A 344
ASP A  84
ARG A 355
VAL A 402
ILE A 406
 None
 1.21A 3ihzA-6bszA:
undetectable		 3ihzA-6bszA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		3 / 3 ASP A 342
ARG A 346
ARG A 335
 None
 0.60A 3k37A-6bszA:
undetectable		 3k37A-6bszA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 12 ASP A  45
ARG A 101
ILE A 102
THR A  97
ALA A  37
 None
SO4  A 603 ( 4.7A)
None
None
SO4  A 603 (-4.1A)
 1.33A 3ua1A-6bszA:
undetectable		 3ua1A-6bszA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 10 TYR A 344
ASP A  84
ARG A 355
VAL A 402
ILE A 406
 None
 1.23A 3uf8A-6bszA:
undetectable		 3uf8A-6bszA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 10 TYR A 344
ASP A  84
ARG A 355
VAL A 402
ILE A 406
 None
 1.20A 3uqaA-6bszA:
undetectable		 3uqaA-6bszA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 11 TYR A 344
ASP A  84
ARG A 355
VAL A 402
ILE A 406
 None
 1.23A 3vawA-6bszA:
undetectable		 3vawA-6bszA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		4 / 4 LEU A 443
ILE A 174
GLY A 444
PHE A 461
 None
 1.07A 4dc3A-6bszA:
3.4		 4dc3A-6bszA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 11 TYR A 344
ASP A  84
ARG A 355
VAL A 402
ILE A 406
 None
 1.37A 4dz2A-6bszA:
undetectable
4dz2B-6bszA:
undetectable		 4dz2A-6bszA:
17.70
4dz2B-6bszA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 10 TYR A 344
ASP A  84
ARG A 355
VAL A 402
ILE A 406
 None
 1.29A 4dz3A-6bszA:
undetectable		 4dz3A-6bszA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 10 TYR A 344
ASP A  84
ARG A 355
VAL A 402
ILE A 406
 None
 1.19A 4dz3B-6bszA:
undetectable		 4dz3B-6bszA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 12 ILE A 151
SER A  39
ILE A  40
ASN A 356
LEU A  80
 None
SO4  A 603 (-2.6A)
None
None
None
 1.15A 4gh8A-6bszA:
3.1		 4gh8A-6bszA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		3 / 4 SER A 308
GLY A 225
GLU A 256
 None
 0.57A 4juoA-6bszA:
undetectable
4juoC-6bszA:
3.5		 4juoA-6bszA:
10.16
4juoC-6bszA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PL1_A_SAMA401_0
(DUAL-SPECIFICITY RNA
METHYLTRANSFERASE
RLMN)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 11 PHE A 192
PRO A  53
SER A 178
ILE A 160
ASN A 164
 None
None
GGL  A 601 (-4.6A)
None
None
 1.34A 4pl1A-6bszA:
1.0		 4pl1A-6bszA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		4 / 4 PHE A 281
ASP A 309
GLY A 231
SER A 308
 None
GGL  A 601 (-2.8A)
None
None
 1.24A 4xp9C-6bszA:
undetectable		 4xp9C-6bszA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 10 TYR A 471
GLY A 228
PHE A 281
SER A 310
GLY A 307
 None
 1.43A 4xpbA-6bszA:
undetectable		 4xpbA-6bszA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 11 TYR A 344
ASP A  84
VAL A 402
ILE A 406
ILE A  86
 None
 1.19A 5d75A-6bszA:
undetectable		 5d75A-6bszA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		6 / 12 GLY A  72
ALA A 177
TYR A 176
ALA A 153
ASP A 104
GLY A 228
 None
GGL  A 601 (-3.5A)
None
None
None
None
 1.18A 5hesB-6bszA:
undetectable		 5hesB-6bszA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 11 TYR A 344
ASP A  84
ARG A 355
VAL A 402
ILE A 406
 None
 1.24A 5huaA-6bszA:
undetectable		 5huaA-6bszA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 11 TYR A 344
ASP A  84
ARG A 355
VAL A 402
ILE A 406
 None
 1.24A 5hw8E-6bszA:
undetectable		 5hw8E-6bszA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 11 TYR A 344
ASP A  84
ARG A 355
VAL A 402
ILE A 406
 None
 1.21A 5hwcA-6bszA:
undetectable		 5hwcA-6bszA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		4 / 6 ILE A 279
VAL A 245
VAL A 218
SER A 239
 None
 0.90A 5jwaH-6bszA:
3.2		 5jwaH-6bszA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_1
(PROTEASE E35D-APV)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 9 ALA A 112
ASP A 109
GLY A 152
ILE A 151
VAL A  54
 None
 1.04A 5kr0A-6bszA:
undetectable		 5kr0A-6bszA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		5 / 12 ILE A  83
GLY A  99
TYR A 410
ALA A  82
MET A  79
 None
 1.28A 5n0xB-6bszA:
undetectable		 5n0xB-6bszA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		4 / 6 TYR A 319
VAL A 318
ILE A 315
GLU A  70
 None
 0.97A 5z3jA-6bszA:
undetectable		 5z3jA-6bszA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8
(Homo
sapiens) 		4 / 6 ASN A 186
SER A 193
ARG A 194
ARG A 447
 None
 1.15A 6dwdA-6bszA:
undetectable
6dwdC-6bszA:
undetectable		 6dwdA-6bszA:
undetectable
6dwdC-6bszA:
undetectable