SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bt4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 6bt4 S-LAYER PROTEIN SAP
(Bacillus
anthracis) 		4 / 4 VAL A 191
ALA A 196
LEU A 138
PHE A 199
 None
None
None
SO4  A 302 (-4.5A)
 0.96A 1q97B-6bt4A:
undetectable		 1q97B-6bt4A:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 6bt4 S-LAYER PROTEIN SAP
(Bacillus
anthracis) 		4 / 6 PHE A  95
ILE A 107
VAL A 110
ALA A  76
 None
 0.93A 2j5mA-6bt4A:
undetectable		 2j5mA-6bt4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 6bt4 S-LAYER PROTEIN SAP
(Bacillus
anthracis) 		5 / 12 SER A 133
ALA A 135
LEU A 138
ALA A  73
VAL A 110
 KPM  A 301 (-3.5A)
None
None
None
None
 1.28A 2yvlC-6bt4A:
undetectable		 2yvlC-6bt4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 6bt4 S-LAYER PROTEIN SAP
(Bacillus
anthracis) 		4 / 8 ILE A 200
LYS A 189
ILE A 129
GLY A  67
 None
 0.96A 4hdlA-6bt4A:
undetectable		 4hdlA-6bt4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 6bt4 S-LAYER PROTEIN SAP
(Bacillus
anthracis) 		4 / 8 ALA A 169
LEU A 138
ILE A 129
VAL A 191
 None
 0.83A 5nujA-6bt4A:
undetectable		 5nujA-6bt4A:
15.29