SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6btg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		5 / 12 ILE A 118
CYH A 179
LEU A 159
VAL A 172
ARG A 149
 None
 1.10A 2bxfA-6btgA:
undetectable		 2bxfA-6btgA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_E_H4BE1004_1
(HYPOTHETICAL PROTEIN
PH0634)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		5 / 11 HIS A 157
HIS A  97
HIS A  95
THR A 132
GLU A  76
 MN  A 301 ( 3.2A)
MN  A 301 ( 3.3A)
MN  A 301 (-3.3A)
None
13P  A 302 ( 3.6A)
 1.16A 2dttD-6btgA:
undetectable
2dttE-6btgA:
undetectable		 2dttD-6btgA:
24.79
2dttE-6btgA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		3 / 3 ARG A 150
GLY A 122
PRO A 123
 None
 0.75A 2hreD-6btgA:
undetectable		 2hreD-6btgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		4 / 8 HIS A  97
GLY A  28
ASN A  29
PHE A 133
 MN  A 301 ( 3.3A)
13P  A 302 (-3.4A)
13P  A 302 (-3.8A)
13P  A 302 ( 4.9A)
 1.21A 3ccfA-6btgA:
undetectable		 3ccfA-6btgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		3 / 3 MET A 200
CYH A 179
PRO A 112
 None
 1.24A 3h52C-6btgA:
undetectable		 3h52C-6btgA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		5 / 12 ARG A  35
TYR A  83
THR A  96
ALA A 169
ILE A  90
 None
 1.19A 3lcvB-6btgA:
undetectable		 3lcvB-6btgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		4 / 7 ILE A  42
LEU A  81
GLU A  76
ALA A 139
 None
None
13P  A 302 ( 3.6A)
None
 0.85A 3r9tB-6btgA:
undetectable		 3r9tB-6btgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		5 / 12 GLY A 122
ARG A  87
LEU A  93
VAL A 172
ALA A 173
 None
 1.13A 3t7vA-6btgA:
undetectable		 3t7vA-6btgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		3 / 3 ASN A 124
GLU A 110
ARG A 126
 None
 1.10A 3wxoA-6btgA:
undetectable		 3wxoA-6btgA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		5 / 12 HIS A  97
LEU A 138
ILE A 160
HIS A  95
GLU A  76
 MN  A 301 ( 3.3A)
None
None
MN  A 301 (-3.3A)
13P  A 302 ( 3.6A)
 1.43A 4r88B-6btgA:
undetectable		 4r88B-6btgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		5 / 12 HIS A  97
LEU A 138
ILE A 160
HIS A  95
GLU A  76
 MN  A 301 ( 3.3A)
None
None
MN  A 301 (-3.3A)
13P  A 302 ( 3.6A)
 1.44A 4r88C-6btgA:
undetectable		 4r88C-6btgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		5 / 12 HIS A  97
LEU A 138
ILE A 160
HIS A  95
GLU A  76
 MN  A 301 ( 3.3A)
None
None
MN  A 301 (-3.3A)
13P  A 302 ( 3.6A)
 1.41A 4r88D-6btgA:
undetectable		 4r88D-6btgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		5 / 12 HIS A  97
LEU A 138
ILE A 160
HIS A  95
GLU A  76
 MN  A 301 ( 3.3A)
None
None
MN  A 301 (-3.3A)
13P  A 302 ( 3.6A)
 1.43A 4r88E-6btgA:
undetectable		 4r88E-6btgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		5 / 12 HIS A  97
LEU A 138
ILE A 160
HIS A  95
GLU A  76
 MN  A 301 ( 3.3A)
None
None
MN  A 301 (-3.3A)
13P  A 302 ( 3.6A)
 1.43A 4r88F-6btgA:
undetectable		 4r88F-6btgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		4 / 7 LEU A 159
GLU A  76
ILE A 166
VAL A  94
 None
13P  A 302 ( 3.6A)
None
None
 1.15A 5jh7C-6btgA:
undetectable		 5jh7C-6btgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		4 / 5 LEU A 138
THR A  96
ARG A  87
ARG A 149
 None
 1.37A 6ew0B-6btgA:
undetectable		 6ew0B-6btgA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		4 / 5 LEU A 138
THR A  96
ARG A  87
ARG A 149
 None
 1.37A 6ew0D-6btgA:
undetectable		 6ew0D-6btgA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		4 / 5 LEU A 138
THR A  96
ARG A  87
ARG A 149
 None
 1.37A 6ew0H-6btgA:
undetectable		 6ew0H-6btgA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 6btg FUCULOSE PHOSPHATE
ALDOLASE
(Bacillus
thuringiensis) 		4 / 5 LEU A 138
THR A  96
ARG A  87
ARG A 149
 None
 1.37A 6ew0I-6btgA:
undetectable		 6ew0I-6btgA:
22.47