SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bv2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 5 HIS A 383
LEU A 274
LEU A 499
GLY A 391
 ZN  A1035 (-3.2A)
None
None
None
 1.13A 1a4lB-6bv2A:
undetectable		 1a4lB-6bv2A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 7 ILE A 430
TYR A 411
PHE A 408
PHE A 491
 None
SO4  A1030 (-4.6A)
None
None
 1.21A 1e71M-6bv2A:
undetectable		 1e71M-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 7 ILE A 430
TYR A 411
PHE A 408
PHE A 491
 None
SO4  A1030 (-4.6A)
None
None
 1.22A 1e72M-6bv2A:
undetectable		 1e72M-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 6 LEU A 934
GLU A 916
THR A 941
ALA A 937
 None
 1.24A 1etb2-6bv2A:
undetectable		 1etb2-6bv2A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 PHE A 627
PHE A 545
ILE A 470
SER A 477
MET A 481
 None
 1.39A 1fm4A-6bv2A:
undetectable		 1fm4A-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 HIS A 383
GLU A 384
HIS A 387
GLU A 406
TYR A 472
 ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
ZN  A1035 (-3.2A)
ZN  A1035 ( 2.2A)
SO4  A1032 ( 4.1A)
 0.78A 1j36A-6bv2A:
6.8		 1j36A-6bv2A:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 HIS A 383
GLU A 384
HIS A 387
GLU A 406
TYR A 472
 ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
ZN  A1035 (-3.2A)
ZN  A1035 ( 2.2A)
SO4  A1032 ( 4.1A)
 0.79A 1j36B-6bv2A:
2.7		 1j36B-6bv2A:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_A_X8ZA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 11 HIS A 383
GLU A 384
HIS A 387
GLU A 406
TYR A 472
 ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
ZN  A1035 (-3.2A)
ZN  A1035 ( 2.2A)
SO4  A1032 ( 4.1A)
 0.77A 1j37A-6bv2A:
2.0		 1j37A-6bv2A:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_B_X8ZB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 11 HIS A 383
GLU A 384
HIS A 387
GLU A 406
TYR A 472
 ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
ZN  A1035 (-3.2A)
ZN  A1035 ( 2.2A)
SO4  A1032 ( 4.1A)
 0.77A 1j37B-6bv2A:
6.8		 1j37B-6bv2A:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 HIS A 383
GLU A 384
HIS A 387
GLU A 406
TYR A 472
 ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
ZN  A1035 (-3.2A)
ZN  A1035 ( 2.2A)
SO4  A1032 ( 4.1A)
 0.76A 1o86A-6bv2A:
6.7		 1o86A-6bv2A:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 4 SER A 585
VAL A 617
PHE A 627
VAL A 582
 None
 1.44A 1o86A-6bv2A:
6.7		 1o86A-6bv2A:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		6 / 12 ALA A 348
HIS A 383
GLU A 384
HIS A 387
GLU A 406
TYR A 472
 SO4  A1027 (-4.3A)
ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
ZN  A1035 (-3.2A)
ZN  A1035 ( 2.2A)
SO4  A1032 ( 4.1A)
 0.71A 2c6nA-6bv2A:
4.7		 2c6nA-6bv2A:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 HIS A 383
GLU A 384
HIS A 387
GLU A 406
TYR A 472
 ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
ZN  A1035 (-3.2A)
ZN  A1035 ( 2.2A)
SO4  A1032 ( 4.1A)
 0.74A 2c6nB-6bv2A:
5.4		 2c6nB-6bv2A:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 7 TRP A 636
GLU A 633
PRO A 672
ALA A 666
 None
 1.38A 2ejgB-6bv2A:
undetectable		 2ejgB-6bv2A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 ASN A 328
LEU A 495
HIS A 326
 NAG  A1014 (-1.8A)
None
None
 0.87A 2q6fB-6bv2A:
undetectable		 2q6fB-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 9 PHE A 408
ALA A 409
VAL A 412
GLU A 413
 None
ZN  A1035 ( 4.0A)
None
None
 0.68A 2vufA-6bv2A:
undetectable		 2vufA-6bv2A:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8Z_A_X8ZA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 11 HIS A 383
GLU A 384
HIS A 387
GLU A 406
TYR A 472
 ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
ZN  A1035 (-3.2A)
ZN  A1035 ( 2.2A)
SO4  A1032 ( 4.1A)
 0.69A 2x8zA-6bv2A:
2.8		 2x8zA-6bv2A:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 HIS A 383
GLU A 384
HIS A 387
GLU A 406
TYR A 472
 ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
ZN  A1035 (-3.2A)
ZN  A1035 ( 2.2A)
SO4  A1032 ( 4.1A)
 0.72A 2x91A-6bv2A:
2.2		 2x91A-6bv2A:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 7 GLU A 406
HIS A 383
HIS A 387
GLU A 384
 ZN  A1035 ( 2.2A)
ZN  A1035 (-3.2A)
ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
 0.82A 3a6jB-6bv2A:
undetectable		 3a6jB-6bv2A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 8 GLU A 406
HIS A 383
HIS A 387
GLU A 384
 ZN  A1035 ( 2.2A)
ZN  A1035 (-3.2A)
ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
 0.82A 3a6jC-6bv2A:
undetectable		 3a6jC-6bv2A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 8 GLU A 406
HIS A 383
HIS A 387
GLU A 384
 ZN  A1035 ( 2.2A)
ZN  A1035 (-3.2A)
ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
 0.83A 3a6jF-6bv2A:
undetectable		 3a6jF-6bv2A:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 8 GLY A 391
ASN A 392
TRP A 389
PHE A 323
 None
 1.12A 3ccfA-6bv2A:
undetectable		 3ccfA-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 5 HIS A 160
ASP A 114
PRO A  66
LYS A  65
 None
None
SO4  A1034 ( 4.7A)
None
 1.25A 3h1xA-6bv2A:
undetectable		 3h1xA-6bv2A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 5 THR A 941
PHE A 906
ARG A 905
LEU A 704
 None
 1.43A 3qelC-6bv2A:
undetectable		 3qelC-6bv2A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 HIS A 786
SER A 791
ASN A 373
 None
 0.85A 3s8pB-6bv2A:
undetectable		 3s8pB-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 7 ALA A 461
TYR A  70
ARG A  71
ARG A 213
 None
 1.13A 3twpC-6bv2A:
undetectable		 3twpC-6bv2A:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQE_B_DXCB1079_0
(PROTEIN PRGI, CELL
INVASION PROTEIN
SIPD)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 11 PRO A 143
GLN A 110
LEU A 165
TYR A 171
SER A 140
 None
 1.37A 3zqeA-6bv2A:
2.2
3zqeB-6bv2A:
0.0		 3zqeA-6bv2A:
undetectable
3zqeB-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 TRP A 513
TRP A 403
THR A 451
 None
 1.35A 4bboB-6bv2A:
undetectable		 4bboB-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 4 ASN A 861
ALA A 864
GLY A 901
THR A 903
 None
 1.33A 4bboC-6bv2A:
undetectable		 4bboC-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 11 HIS A 383
GLU A 384
HIS A 387
GLU A 406
TYR A 472
 ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
ZN  A1035 (-3.2A)
ZN  A1035 ( 2.2A)
SO4  A1032 ( 4.1A)
 0.76A 4c2pA-6bv2A:
3.7		 4c2pA-6bv2A:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DPR_A_X8ZA702_1
(LEUKOTRIENE A-4
HYDROLASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 9 GLY A 347
HIS A 383
GLU A 384
GLU A 406
TYR A 472
 SO4  A1027 (-3.1A)
ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
ZN  A1035 ( 2.2A)
SO4  A1032 ( 4.1A)
 0.68A 4dprA-6bv2A:
25.0		 4dprA-6bv2A:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 7 ALA A 809
PHE A 773
ALA A 797
ALA A 828
 None
 0.84A 4du2B-6bv2A:
undetectable		 4du2B-6bv2A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 ARG A 720
LYS A 721
LYS A 717
 SO4  A1029 (-2.4A)
None
None
 1.37A 4k50A-6bv2A:
1.9		 4k50A-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 ARG A 720
LYS A 721
LYS A 717
 SO4  A1029 (-2.4A)
None
None
 1.39A 4k50E-6bv2A:
1.9		 4k50E-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 ARG A 720
LYS A 721
LYS A 717
 SO4  A1029 (-2.4A)
None
None
 1.37A 4k50I-6bv2A:
0.0		 4k50I-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 7 MET A 690
ARG A 480
SER A 698
VAL A 435
 None
SO4  A1030 (-4.6A)
None
None
 1.40A 4kmmA-6bv2A:
undetectable		 4kmmA-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 6 PHE A 390
TYR A 327
LEU A 499
THR A 507
 None
 1.34A 4paeA-6bv2A:
undetectable		 4paeA-6bv2A:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 ILE A 793
THR A 792
ALA A 757
LEU A 789
PHE A 727
 None
 1.03A 4pbhA-6bv2A:
undetectable		 4pbhA-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 ALA A 276
ALA A 340
ILE A 339
GLY A 353
GLN A 388
 None
 0.97A 4r38A-6bv2A:
undetectable		 4r38A-6bv2A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 ALA A 276
ALA A 340
ILE A 339
GLY A 353
GLN A 388
 None
 0.98A 4r38B-6bv2A:
undetectable		 4r38B-6bv2A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 ALA A 276
ALA A 340
ILE A 339
GLY A 353
GLN A 388
 None
 0.94A 4r38C-6bv2A:
undetectable		 4r38C-6bv2A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 ALA A 276
ALA A 340
ILE A 339
GLY A 353
GLN A 388
 None
 0.95A 4r38D-6bv2A:
undetectable		 4r38D-6bv2A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 ALA A 276
ALA A 340
ILE A 339
GLY A 353
GLN A 388
 None
 0.90A 4r3aB-6bv2A:
undetectable		 4r3aB-6bv2A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 ALA A 340
ILE A 339
ILE A 381
GLY A 353
GLN A 388
 None
 0.99A 4r3aB-6bv2A:
undetectable		 4r3aB-6bv2A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		6 / 12 GLN A 208
HIS A 383
GLU A 384
HIS A 387
GLU A 406
TYR A 472
 ILE  A1024 (-4.2A)
ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
ZN  A1035 (-3.2A)
ZN  A1035 ( 2.2A)
SO4  A1032 ( 4.1A)
 0.72A 4r7lA-6bv2A:
30.3		 4r7lA-6bv2A:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		6 / 12 HIS A 383
GLU A 384
HIS A 387
TRP A 399
GLU A 406
TYR A 472
 ZN  A1035 (-3.2A)
ILE  A1024 ( 4.1A)
ZN  A1035 (-3.2A)
SO4  A1025 (-3.5A)
ZN  A1035 ( 2.2A)
SO4  A1032 ( 4.1A)
 0.48A 4r7lA-6bv2A:
30.3		 4r7lA-6bv2A:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 5 ILE A 479
PHE A 502
SER A 410
ASP A 401
 None
NAG  A1016 (-4.5A)
None
None
 1.34A 4rzvB-6bv2A:
undetectable		 4rzvB-6bv2A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 8 GLY A 544
GLN A 542
SER A 447
HIS A 561
 None
 0.95A 4wryA-6bv2A:
undetectable		 4wryA-6bv2A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 8 GLY A 544
GLN A 542
SER A 447
HIS A 561
 None
 0.95A 4wrzA-6bv2A:
undetectable		 4wrzA-6bv2A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 HIS A 786
SER A 791
ASN A 373
 None
 0.91A 5cprB-6bv2A:
undetectable		 5cprB-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 5 GLU A 350
ALA A 348
GLU A 384
GLU A 406
 ILE  A1024 (-3.1A)
SO4  A1027 (-4.3A)
ILE  A1024 ( 4.1A)
ZN  A1035 ( 2.2A)
 1.35A 5dwkC-6bv2A:
undetectable		 5dwkC-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FEP_A_SAMA407_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 GLN A 338
SER A 336
GLY A 353
LEU A 333
TYR A 357
 None
 1.18A 5fepA-6bv2A:
undetectable		 5fepA-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FES_A_SAMA408_0
([FEFE] HYDROGENASE
MATURASE SUBUNIT
HYDE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 GLN A 338
SER A 336
GLY A 353
LEU A 333
TYR A 357
 None
 1.18A 5fesA-6bv2A:
undetectable		 5fesA-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 4 ASN A 866
LEU A 838
SER A 862
LEU A 829
 None
 1.27A 5kb5A-6bv2A:
undetectable		 5kb5A-6bv2A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 9 ASP A 442
ILE A 470
GLY A 475
ILE A 479
THR A 451
 None
 1.27A 5kr2C-6bv2A:
undetectable		 5kr2C-6bv2A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 HIS A 962
GLU A 961
TRP A 958
 None
 0.75A 5odiD-6bv2A:
undetectable		 5odiD-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 HIS A 962
GLU A 961
TRP A 958
 None
 0.77A 5odqD-6bv2A:
undetectable		 5odqD-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 HIS A 962
GLU A 961
TRP A 958
 None
 0.71A 5odrD-6bv2A:
undetectable		 5odrD-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 4 HIS A 387
HIS A 383
TYR A 472
GLU A 406
 ZN  A1035 (-3.2A)
ZN  A1035 (-3.2A)
SO4  A1032 ( 4.1A)
ZN  A1035 ( 2.2A)
 1.40A 5pahA-6bv2A:
undetectable		 5pahA-6bv2A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 VAL A 431
VAL A 435
GLN A 628
 None
 0.63A 5qgjA-6bv2A:
undetectable		 5qgjA-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 VAL A 431
VAL A 435
GLN A 628
 None
 0.58A 5qgnA-6bv2A:
undetectable		 5qgnA-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 VAL A 431
VAL A 435
GLN A 628
 None
 0.61A 5qgyA-6bv2A:
undetectable		 5qgyA-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 VAL A 431
VAL A 435
GLN A 628
 None
 0.62A 5qgzA-6bv2A:
undetectable		 5qgzA-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 VAL A 431
VAL A 435
GLN A 628
 None
 0.62A 5qh0A-6bv2A:
undetectable		 5qh0A-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 VAL A 431
VAL A 435
GLN A 628
 None
 0.60A 5qh2A-6bv2A:
undetectable		 5qh2A-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 VAL A 431
VAL A 435
GLN A 628
 None
 0.62A 5qh3A-6bv2A:
undetectable		 5qh3A-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 VAL A 431
VAL A 435
GLN A 628
 None
 0.60A 5qh5A-6bv2A:
undetectable		 5qh5A-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 VAL A 431
VAL A 435
GLN A 628
 None
 0.62A 5qh6A-6bv2A:
undetectable		 5qh6A-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 VAL A 431
VAL A 435
GLN A 628
 None
 0.62A 5qh7A-6bv2A:
undetectable		 5qh7A-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 VAL A 431
VAL A 435
GLN A 628
 None
 0.67A 5qhaA-6bv2A:
undetectable		 5qhaA-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		3 / 3 VAL A 431
VAL A 435
GLN A 628
 None
 0.64A 5qhhA-6bv2A:
undetectable		 5qhhA-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAC_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 PHE A 663
ASP A 661
LEU A 647
PRO A 651
ILE A 650
 None
 1.49A 5uacC-6bv2A:
undetectable		 5uacC-6bv2A:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 7 GLY A 407
TRP A 403
ASP A 468
TYR A 472
 None
None
None
SO4  A1032 ( 4.1A)
 1.41A 6ag0A-6bv2A:
undetectable		 6ag0A-6bv2A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC609_0
(ALPHA-AMYLASE)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 7 GLY A 407
TRP A 403
ASP A 468
TYR A 472
 None
None
None
SO4  A1032 ( 4.1A)
 1.38A 6ag0C-6bv2A:
undetectable		 6ag0C-6bv2A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		5 / 12 LEU A 320
ALA A 409
ASN A 392
VAL A 355
TYR A 357
 None
ZN  A1035 ( 4.0A)
None
None
None
 1.32A 6drxA-6bv2A:
undetectable		 6drxA-6bv2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_1
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 6bv2 AMINOPEPTIDASE N
(Sus
scrofa) 		4 / 5 ASN A 243
GLN A 206
TYR A 472
MET A 270
 None
ILE  A1024 (-3.2A)
SO4  A1032 ( 4.1A)
None
 0.78A 6hlpA-6bv2A:
1.3		 6hlpA-6bv2A:
undetectable