SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bvp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		6 / 12 LEU A  81
CYH A 106
VAL A  41
GLY A  42
LEU A  21
LEU A  68
 None
 1.42A 3ijdB-6bvpA:
undetectable		 3ijdB-6bvpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		5 / 11 PHE A 121
ASP A 119
GLU A 110
HIS A  51
ILE A 142
 None
None
FE2  A 202 ( 4.6A)
FE2  A 202 (-3.3A)
None
 1.06A 3o94A-6bvpA:
undetectable		 3o94A-6bvpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		5 / 11 PHE A 121
ASP A 119
GLU A 110
HIS A  51
ILE A 142
 None
None
FE2  A 202 ( 4.6A)
FE2  A 202 (-3.3A)
None
 1.07A 3o94D-6bvpA:
undetectable		 3o94D-6bvpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		4 / 8 TRP A  31
VAL A  40
LEU A 107
LEU A  62
 None
 0.80A 3u5kA-6bvpA:
undetectable		 3u5kA-6bvpA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		4 / 7 TRP A  31
VAL A  40
LEU A 107
LEU A  62
 None
 0.79A 3u5kB-6bvpA:
undetectable		 3u5kB-6bvpA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		4 / 8 TRP A  31
VAL A  40
LEU A 107
LEU A  62
 None
 0.92A 3u5kC-6bvpA:
undetectable		 3u5kC-6bvpA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		4 / 8 TRP A  31
VAL A  40
LEU A 107
LEU A  62
 None
 0.93A 3u5kD-6bvpA:
undetectable		 3u5kD-6bvpA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		3 / 3 ARG A 111
MET A 117
ARG A 113
 None
 1.39A 3uvvA-6bvpA:
undetectable		 3uvvA-6bvpA:
14.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		7 / 7 HIS A  51
ASP A  53
GLU A  57
HIS A  95
PRO A  97
VAL A 108
GLU A 110
 FE2  A 202 (-3.3A)
None
FE2  A 202 (-2.2A)
FE2  A 202 (-3.4A)
None
None
FE2  A 202 ( 4.6A)
 0.46A 4hvrA-6bvpA:
29.2		 4hvrA-6bvpA:
72.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		3 / 3 HIS A  17
GLU A  16
TRP A  13
 None
 0.81A 5odiD-6bvpA:
undetectable		 5odiD-6bvpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		3 / 3 HIS A  17
GLU A  16
TRP A  13
 None
 0.79A 5odqD-6bvpA:
undetectable		 5odqD-6bvpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		3 / 3 HIS A  17
GLU A  16
TRP A  13
 None
 0.76A 5odrD-6bvpA:
undetectable		 5odrD-6bvpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJY_A_BEZA304_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		3 / 3 MET A 117
GLU A  57
ARG A 113
 None
FE2  A 202 (-2.2A)
None
 0.98A 5tjyA-6bvpA:
undetectable		 5tjyA-6bvpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 6bvp 3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE
(Cupriavidus
metallidurans) 		3 / 3 MET A 117
GLU A  57
ARG A 113
 None
FE2  A 202 (-2.2A)
None
 0.98A 5tjzA-6bvpA:
undetectable		 5tjzA-6bvpA:
undetectable