SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6bwl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 6bwl PAL
(Bacillus
thuringiensis) 		4 / 6 PHE A  11
LEU A  79
VAL A 226
VAL A 219
 NAD  A 401 (-4.8A)
NAD  A 401 (-4.4A)
None
None
 1.10A 1e7aB-6bwlA:
0.4		 1e7aB-6bwlA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 6bwl PAL
(Bacillus
thuringiensis) 		4 / 7 TYR A 163
THR A 100
THR A 103
VAL A 169
 None
 1.19A 1tv8B-6bwlA:
undetectable		 1tv8B-6bwlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 6bwl PAL
(Bacillus
thuringiensis) 		5 / 9 LEU A 253
ILE A 250
GLY A 210
SER A 258
LEU A 204
 None
UDP  A 402 (-4.0A)
EDO  A 404 ( 4.8A)
None
None
 1.12A 2qmmA-6bwlA:
undetectable		 2qmmA-6bwlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 6bwl PAL
(Bacillus
thuringiensis) 		5 / 9 LEU A 253
ILE A 250
GLY A 210
SER A 258
LEU A 204
 None
UDP  A 402 (-4.0A)
EDO  A 404 ( 4.8A)
None
None
 1.09A 3ai9X-6bwlA:
undetectable		 3ai9X-6bwlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 6bwl PAL
(Bacillus
thuringiensis) 		5 / 12 GLY A 149
SER A  88
SER A 274
HIS A 271
ALA A 144
 None
 1.20A 3d91A-6bwlA:
undetectable		 3d91A-6bwlA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6bwl PAL
(Bacillus
thuringiensis) 		5 / 9 GLY A  10
ASP A  31
ILE A  29
VAL A  17
VAL A  16
 NAD  A 401 (-3.1A)
NAD  A 401 (-2.6A)
None
None
None
 1.09A 3fi0F-6bwlA:
undetectable		 3fi0F-6bwlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 6bwl PAL
(Bacillus
thuringiensis) 		4 / 8 ASP A 215
ASP A 247
ASP A 221
ASP A 300
 EDO  A 405 (-4.4A)
NA  A 409 (-3.3A)
None
None
 1.00A 3havA-6bwlA:
undetectable		 3havA-6bwlA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 6bwl PAL
(Bacillus
thuringiensis) 		5 / 12 GLY A 243
GLY A 245
ASP A 215
GLU A 293
ASN A 241
 None
None
EDO  A 405 (-4.4A)
None
None
 1.16A 3t7sA-6bwlA:
5.4		 3t7sA-6bwlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 6bwl PAL
(Bacillus
thuringiensis) 		5 / 12 GLY A 243
GLY A 245
ASP A 215
GLU A 293
ASN A 241
 None
None
EDO  A 405 (-4.4A)
None
None
 1.13A 3t7sB-6bwlA:
5.9		 3t7sB-6bwlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 6bwl PAL
(Bacillus
thuringiensis) 		5 / 12 GLY A 243
GLY A 245
ASP A 215
GLU A 293
ASN A 241
 None
None
EDO  A 405 (-4.4A)
None
None
 1.14A 3t7sD-6bwlA:
5.3		 3t7sD-6bwlA:
undetectable